Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

(2011) Bolin Liu et al.   CELL CYCLE

High Cancer Risk in Peutz–Jeghers Syndrome: A Systematic Review and Surveillance Recommendations

(2010) M G F van Lier et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Chemoprevention Meets Glucose Control

(2010) J. A. Engelman et al.   Cancer Prevention Research

Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis

(2010) R. M. Memmott et al.   Cancer Prevention Research

Metformin and Other Biguanides in Oncology: Advancing the Research Agenda

(2010) M. Pollak   Cancer Prevention Research

Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical Trial

(2010) K. Hosono et al.   Cancer Prevention Research

Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes

(2010) R. Novosyadlyy et al.   CANCER RESEARCH

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer

(2010) M. Bodmer et al.   DIABETES CARE

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

(2010) Carolyn Algire et al.   ENDOCRINE-RELATED CANCER

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Do Cancer Cells Care If Their Host Is Hungry?

(2009) Michael Pollak   Cell Metabolism

New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes

(2009) G. Libby et al.   DIABETES CARE

Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes: ZODIAC-16

(2009) G. W.D. Landman et al.   DIABETES CARE

The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

(2009) C. J. Currie et al.   DIABETOLOGIA

Diabetes and cancer

(2009) Paolo Vigneri et al.   ENDOCRINE-RELATED CANCER

Tumours with PI3K activation are resistant to dietary restriction

(2009) Nada Y. Kalaany et al.   NATURE

Somatic LKB1 Mutations Promote Cervical Cancer Progression

(2009) Shana N. Wingo et al.   PLoS One

Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

(2008) Xu Huang et al.   BIOCHEMICAL JOURNAL

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

The Effects of Adiponectin and Metformin on Prostate and Colon Neoplasia Involve Activation of AMP-Activated Protein Kinase

(2008) M. Zakikhani et al.   Cancer Prevention Research

Metformin suppresses intestinal polyp growth in ApcMin/+ mice

(2008) Ayako Tomimoto et al.   CANCER SCIENCE

Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth

(2008) C. Algire et al.   ENDOCRINE-RELATED CANCER

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

(2008) James A. Dykens et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY