Platelet 12-LOX is essential for Fc RIIa-mediated platelet activation

Synthesis and Structure–Activity Relationship Studies of 4-((2-Hydroxy-3-methoxybenzyl)amino)benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase

(2014) Diane K. Luci et al.   JOURNAL OF MEDICINAL CHEMISTRY

Integrin αIIbβ3

(2013) Kamila Bledzka et al.   CIRCULATION RESEARCH

Platelet ITAM signaling

(2013) Wolfgang Bergmeier et al.   CURRENT OPINION IN HEMATOLOGY

12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity

(2013) Jennifer Yeung et al.   THROMBOSIS AND HAEMOSTASIS

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

(2012) H. Zhi et al.   BLOOD

Identification of the Orphan G Protein-coupled Receptor GPR31 as a Receptor for 12-(S)-Hydroxyeicosatetraenoic Acid

(2011) Yande Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelets and the innate immune system: mechanisms of bacterial-induced platelet activation

(2011) D. COX et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Novel platelet activation receptor CLEC-2: from discovery to prospects

(2011) K. SUZUKI-INOUE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protease-Activated Receptor Signaling in Platelets Activates Cytosolic Phospholipase A 2α Differently for Cyclooxygenase-1 and 12-Lipoxygenase Catalysis

(2010) Michael Holinstat et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase

(2010) Lloyd T. Morgan et al.   BIOCHEMICAL JOURNAL

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

(2010) M. P. Reilly et al.   BLOOD

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation

(2010) Christopher P. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences

(2008) Ho-Sup Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

(2008) Naohide Watanabe et al.   JOURNAL OF CELL BIOLOGY

Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice

(2008) T. MEYER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE