A von Willebrand factor fragment containing the D'D3 domains is sufficient to stabilize coagulation factor VIII in mice

Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project

(2013) J. M. Johnsen et al.   BLOOD

A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models

(2013) H. R. Stennicke et al.   BLOOD

Pharmacokinetics and safety of a novel recombinant human von Willebrand factor manufactured with a plasma-free method: a prospective clinical trial

(2013) P. M. Mannucci et al.   BLOOD

Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A

(2013) J. Mahlangu et al.   BLOOD

The hope and reality of long-acting hemophilia products

(2012) Steven W. Pipe   AMERICAN JOURNAL OF HEMATOLOGY

Thermodynamic Analysis of the Interaction of Factor VIII with von Willebrand Factor

(2012) Jordan D. Dimitrov et al.   BIOCHEMISTRY

Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs

(2012) J. A. Dumont et al.   BLOOD

Distinct Roles of Ser-764 and Lys-773 at the N Terminus of von Willebrand Factor in Complex Assembly with Coagulation Factor VIII

(2012) Lydia Castro-Núñez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association

(2012) K. C. Desch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

(2011) C. M. Pruss et al.   BLOOD

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients

(2011) A. D. Shapiro et al.   BLOOD

IL-15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization

(2011) Kai-ping Han et al.   CYTOKINE

Biology and physics of von Willebrand factor concatamers

(2011) T. A. SPRINGER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cleavage of von Willebrand Factor by Granzyme M Destroys Its Factor VIII Binding Capacity

(2011) Martine J. Hollestelle et al.   PLoS One

Analysis of von Willebrand Factor Multimers by Simultaneous High- and Low-Resolution Vertical SDS-Agarose Gel Electrophoresis and Cy5-Labeled Antibody High-Sensitivity Fluorescence Detection

(2010) Helmut W. Ott et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function

(2010) J. Lu et al.   BLOOD

Prolonged activity of factor IX as a monomeric Fc fusion protein

(2010) R. T. Peters et al.   BLOOD

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

(2010) B. Mei et al.   BLOOD

Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice

(2009) J. A. Shavit et al.   BLOOD

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

(2009) Héctor Pérez Montoyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restoration of Plasma von Willebrand Factor Deficiency Is Sufficient to Correct Thrombus Formation After Gene Therapy for Severe von Willebrand Disease

(2008) Simon F. De Meyer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Altered thrombus formation in von Willebrand factor-deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa

(2008) I. Marx et al.   BLOOD

Assembly of Weibel Palade body-like tubules from N-terminal domains of von Willebrand factor

(2008) R.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extending half-life in coagulation factors: where do we stand?

(2008) David Lillicrap   THROMBOSIS RESEARCH