A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models
出版年份 2013 全文链接
标题
A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models
作者
关键词
-
出版物
BLOOD
Volume 121, Issue 11, Pages 2108-2116
出版商
American Society of Hematology
发表日期
2013-01-19
DOI
10.1182/blood-2012-01-407494
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice
- (2012) A. Wroblewska et al. BLOOD
- Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients
- (2012) J. S. Powell et al. BLOOD
- Pioneering designs for recombinant coagulation factors
- (2012) Stefan Schulte THROMBOSIS RESEARCH
- Requirements for immune recognition and processing of factor VIII by antigen-presenting cells
- (2011) Simon D. van Haren et al. BLOOD REVIEWS
- Polymer therapeutics as nanomedicines: new perspectives
- (2011) Ruth Duncan CURRENT OPINION IN BIOTECHNOLOGY
- Bioequivalence between two serum-free recombinant factor VIII preparations (N8 and ADVATE®) - an open-label, sequential dosing pharmacokinetic study in patients with severe haemophilia A
- (2011) U. MARTINOWITZ et al. HAEMOPHILIA
- Pharmacokinetics and pharmacodynamics of a new recombinant FVIII (N8) in haemophilia A mice
- (2011) T. ELM et al. HAEMOPHILIA
- Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain
- (2011) Eszter Herczenik et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment
- (2010) B. Mei et al. BLOOD
- Functional characteristics of N8, a new recombinant FVIII
- (2010) M. L. S. CHRISTIANSEN et al. HAEMOPHILIA
- NMR structure determination of tick anticoagulant peptide (TAP)
- (2010) Marguerita S.L. Lim-Wilby et al. PROTEIN SCIENCE
- PEG-modified biopharmaceuticals
- (2009) Pascal Bailon et al. Expert Opinion on Drug Delivery
- Purification and characterization of a new recombinant factor VIII (N8)
- (2009) L. THIM et al. HAEMOPHILIA
- A ferric chloride induced arterial injury model used as haemostatic effect model
- (2009) F. MØLLER et al. HAEMOPHILIA
- Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial
- (2008) J Smolen et al. ANNALS OF THE RHEUMATIC DISEASES
- The Pharmacology of PEGylation: Balancing PD with PK to Generate Novel Therapeutics
- (2008) C.Simone Fishburn JOURNAL OF PHARMACEUTICAL SCIENCES
- Hemostatic effect of recombinant factor VIIa, NN1731 and recombinant factor VIII on needle-induced joint bleeding in hemophilia A mice
- (2008) K. ØVLISEN et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation