Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients

(2012) J. S. Powell et al.   BLOOD

Safety and pharmacokinetics of a glycoPEGylated recombinant activated factor VII derivative: a randomized first human dose trial in healthy subjects

(2011) J. MØSS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Prolonged activity of factor IX as a monomeric Fc fusion protein

(2010) R. T. Peters et al.   BLOOD

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

(2010) B. Mei et al.   BLOOD

Viral pathogens

(2010) M. V. RAGNI et al.   HAEMOPHILIA

Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice

(2009) J. Pan et al.   BLOOD

Application of a novel affinity adsorbent for the capture and purification of recombinant Factor VIII compounds

(2009) Justin T. McCue et al.   JOURNAL OF CHROMATOGRAPHY A

Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo

(2008) C. J. van Schooten et al.   BLOOD

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

(2008) A. S. De Groot et al.   BLOOD

Romiplostim

(2008) Douglas B. Cines et al.   NATURE REVIEWS DRUG DISCOVERY

Infused Fc-tagged  -glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice

(2008) J. H. Grubb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex

(2008) Jacky Chi Ki Ngo et al.   STRUCTURE