Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptor
出版年份 2012 全文链接
标题
Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptor
作者
关键词
-
出版物
BIOTECHNOLOGY PROGRESS
Volume 28, Issue 6, Pages 1588-1597
出版商
Wiley
发表日期
2012-09-07
DOI
10.1002/btpr.1631
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Preassociation of IL-15 with IL-15R -IgG1-Fc Enhances Its Activity on Proliferation of NK and CD8+/CD44high T Cells and Its Antitumor Action
- (2014) S. Dubois et al. JOURNAL OF IMMUNOLOGY
- Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
- (2012) R. B. Liu et al. CANCER RESEARCH
- An Antibody Fusion Protein for Cancer Immunotherapy Mimicking IL-15 trans -Presentation at the Tumor Site
- (2012) Vanessa Kermer et al. MOLECULAR CANCER THERAPEUTICS
- A Dose-Escalation and Signal-Generating Study of the Immunocytokine L19-IL2 in Combination with Dacarbazine for the Therapy of Patients with Metastatic Melanoma
- (2011) T. K. Eigentler et al. CLINICAL CANCER RESEARCH
- IL-15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization
- (2011) Kai-ping Han et al. CYTOKINE
- Treatment of Hepatocellular Carcinoma with Adeno-Associated Virus Encoding Interleukin-15 Superagonist
- (2010) Chia-Ming Chang et al. HUMAN GENE THERAPY
- Tumor masses support naive T cell infiltration, activation, and differentiation into effectors
- (2010) Elizabeth D. Thompson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Interleukin-15:Interleukin-15 receptor scaffold for creation of multivalent targeted immune molecules
- (2010) R. L. Wong et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors
- (2010) D. H. Aggen et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Expression, engineering and characterization of the tumor-targeting heterodimeric immunocytokine F8-IL12
- (2010) Roberto Sommavilla et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Trans-presentation: A novel mechanism regulating IL-15 delivery and responses
- (2009) Spencer W. Stonier et al. IMMUNOLOGY LETTERS
- The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness
- (2009) A. S. Chervin et al. JOURNAL OF IMMUNOLOGY
- High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor fusion protein, in metastatic melanoma and colorectal cancer
- (2009) A. Bessard et al. MOLECULAR CANCER THERAPEUTICS
- Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors†‡
- (2008) Lindsay L. Jones et al. BIOCHEMISTRY
- Interleukin-15/Interleukin-15R Complexes Promote Destruction of Established Tumors by Reviving Tumor-Resident CD8+ T Cells
- (2008) M. Epardaud et al. CANCER RESEARCH
- Twelve immunotherapy drugs that could cure cancers
- (2008) Martin A. ‘Mac’ Cheever IMMUNOLOGICAL REVIEWS
- T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity
- (2008) Jennifer D. Stone et al. IMMUNOLOGY
- IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
- (2008) Nicholas D. Huntington et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Exon-3-Encoded Domain of IL-15Rα Contributes to IL-15 High-Affinity Binding and Is Crucial for the IL-15 Antagonistic Effect of Soluble IL-15Rα
- (2008) Grégory Bouchaud et al. JOURNAL OF MOLECULAR BIOLOGY
- Specificity in cancer immunotherapy
- (2008) Andrea Schietinger et al. SEMINARS IN IMMUNOLOGY
- Developing therapeutic proteins by engineering ligand–receptor interactions
- (2008) Douglas S. Jones et al. TRENDS IN BIOTECHNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search