A Bone Anabolic Effect of RANKL in a Murine Model of Osteoporosis Mediated Through FoxP3+CD8 T Cells

Patients with Pediatric Obstructive Sleep Apnea Show Altered T-Cell Populations with a Dominant TH17 Profile

(2014) Martin E. Anderson et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Regulatory Mechanisms of RANKL Presentation to Osteoclast Precursors

(2014) Masashi Honma et al.   Current Osteoporosis Reports

Osteoclast-induced Foxp3+ CD8 T-cells limit bone loss in mice

(2013) Zachary S. Buchwald et al.   BONE

Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems

(2013) Zachary S. Buchwald et al.   Clinical & Developmental Immunology

Mechanisms in Endocrinology: Notch signaling in skeletal health and disease

(2013) Stefano Zanotti et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response

(2013) Samantha L. Bailey-Bucktrout et al.   IMMUNITY

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

Notch Signaling and Bone Remodeling

(2013) Jenna Regan et al.   Current Osteoporosis Reports

Donor-Specific CD8+Foxp3+ T Cells Protect Skin Allografts and Facilitate Induction of Conventional CD4+Foxp3+ Regulatory T Cells

(2012) N. M Lerret et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Denosumab, a RANK Ligand Inhibitor, for Postmenopausal Women with Osteoporosis

(2012) Emily E Sutton et al.   ANNALS OF PHARMACOTHERAPY

Identification and expansion of highly suppressive CD8+FoxP3+ regulatory T cells after experimental allogeneic bone marrow transplantation

(2012) R. J. Robb et al.   BLOOD

Advances in Osteoimmunology: Pathophysiologic Concepts and Treatment Opportunities

(2012) Martina Rauner et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Halofuginone prevents estrogen-deficient osteoporosis in mice

(2012) Carl J. DeSelm et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner

(2012) Carl J. DeSelm et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CD8+CD45RA+CCR7+FOXP3+ T Cells with Immunosuppressive Properties: A Novel Subset of Inducible Human Regulatory T Cells

(2012) M. Suzuki et al.   JOURNAL OF IMMUNOLOGY

Maintaining system homeostasis: the third law of Newtonian immunology

(2012) Ronald N Germain   NATURE IMMUNOLOGY

Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab

(2012) David L. Lacey et al.   NATURE REVIEWS DRUG DISCOVERY

New developments in osteoimmunology

(2012) Hiroshi Takayanagi   Nature Reviews Rheumatology

Osteoclast Activated FoxP3+ CD8+ T-Cells Suppress Bone Resorption in vitro

(2012) Zachary S. Buchwald et al.   PLoS One

Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes

(2012) Chiyoko Sekine et al.   ARTHRITIS RESEARCH & THERAPY

Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity

(2012) Christian T. Mayer et al.   Frontiers in Immunology

Anabolic Effects of Intermittent PTH on Osteoblasts

(2012) Edward M. Greenfield   Current Molecular Pharmacology

CD8+Foxp3+ T cells share developmental and phenotypic features with classical CD4+Foxp3+ regulatory T cells but lack potent suppressive activity

(2011) Christian T. Mayer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Notch Ligand Delta-Like 4 Blockade Alleviates Experimental Autoimmune Encephalomyelitis by Promoting Regulatory T Cell Development

(2011) R. Bassil et al.   JOURNAL OF IMMUNOLOGY

Notch3 and Canonical NF- B Signaling Pathways Cooperatively Regulate Foxp3 Transcription

(2011) A. Barbarulo et al.   JOURNAL OF IMMUNOLOGY

IL-17A and TNF-  Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro

(2011) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

Simplified Models of Biological Networks

(2010) Kim Sneppen et al.   Annual Review of Biophysics

Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells

(2010) H. Li et al.   BLOOD

T cells: Critical bone regulators in health and disease

(2010) Roberto Pacifici   BONE

Immune Inhibitory Ligand CD200 Induction by TLRs and NLRs Limits Macrophage Activation to Protect the Host from Meningococcal Septicemia

(2010) Subhankar Mukhopadhyay et al.   Cell Host & Microbe

The Notch signaling pathway: Transcriptional regulation at Notch target genes

(2009) T. Borggrefe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Evaluation of Pharmaceuticals With a Novel 50-Hour Animal Model of Bone Loss*

(2009) Yoshiya Tomimori et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cross-Presentation by Osteoclasts Induces FoxP3 in CD8+ T Cells

(2009) J. R. Kiesel et al.   JOURNAL OF IMMUNOLOGY

Unique Phenotype of Human Tonsillar and In Vitro-Induced FOXP3+CD8+ T Cells

(2009) K. Siegmund et al.   JOURNAL OF IMMUNOLOGY

Transcriptional regulation ofFoxp3gene: Multiple signal pathways on the road

(2009) Zhu Shen et al.   MEDICINAL RESEARCH REVIEWS

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Phenotypes and tolerances in the design space of biochemical systems

(2009) M. A. Savageau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoimmunology in rheumatic diseases

(2009) Georg Schett   ARTHRITIS RESEARCH & THERAPY

Notch1 and TGF 1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells

(2008) J. B. Samon et al.   BLOOD

Quantitative micro-computed tomography: A non-invasive method to assess equivalent bone mineral density

(2008) Ara Nazarian et al.   BONE

Emerging concepts in CD8+ T regulatory cells

(2008) Jerry Y Niederkorn   CURRENT OPINION IN IMMUNOLOGY

Biodistribution and Plasma Protein Binding of Zoledronic Acid

(2008) H. M. Weiss et al.   DRUG METABOLISM AND DISPOSITION

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

(2008) Susan A Krum et al.   EMBO JOURNAL

Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms

(2008) Hai-Feng Ou-Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

(2008) Robert J Snelgrove et al.   NATURE IMMUNOLOGY