Dietary cocoa protects against colitis-associated cancer by activating the Nrf2/Keap1 pathway

Dietary Non-nutritive Factors in Targeting of Regulatory Molecules in Colorectal Cancer: An Update

(2014) Ashok Kumar Pandurangan et al.   Asian Pacific Journal of Cancer Prevention

Signal Transducer and Activator of Transcription 3 - A Promising Target in Colitis-Associated Cancer

(2014) Ashok Kumar Pandurangan et al.   Asian Pacific Journal of Cancer Prevention

Chemoprevention of dietary digitoflavone on colitis-associated colon tumorigenesis through inducing Nrf2 signaling pathway and inhibition of inflammation

(2014) Yang Yang et al.   Molecular Cancer

Cocoa Polyphenols and Inflammatory Markers of Cardiovascular Disease

(2014) Nasiruddin Khan et al.   Nutrients

Chemopreventive effect of dietary glutamine on colitis-associated colon tumorigenesis in mice

(2013) Y. Tian et al.   CARCINOGENESIS

Protection from inflammatory bowel disease and colitis-associated carcinogenesis with 4-vinyl-2,6-dimethoxyphenol (canolol) involves suppression of oxidative stress and inflammatory cytokines

(2013) Jun Fang et al.   CARCINOGENESIS

Potential for preventive effects of cocoa and cocoa polyphenols in cancer

(2013) Maria Angeles Martin et al.   FOOD AND CHEMICAL TOXICOLOGY

Molecular mechanisms underlying the potential antiobesity-related diseases effect of cocoa polyphenols

(2013) Faisal Ali et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Luteolin, a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through activation of Nrf2 signaling

(2013) Ashok Kumar Pandurangan et al.   TOXICOLOGY MECHANISMS AND METHODS

Preventive Inositol Hexaphosphate Extracted from Rice Bran Inhibits Colorectal Cancer through Involvement of Wnt/β-Catenin and COX-2 Pathways

(2013) Nurul Husna Shafie et al.   Biomed Research International

Immunomodulatory properties of cacao extracts – potential consequences for medical applications

(2013) Kathrin Becker et al.   Frontiers in Pharmacology

Cocoa polyphenols prevent inflammation in the colon of azoxymethane-treated rats and in TNF-α-stimulated Caco-2 cells

(2012) Ildefonso Rodríguez-Ramiro et al.   BRITISH JOURNAL OF NUTRITION

Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice

(2012) T. Kuno et al.   CARCINOGENESIS

iNOS signaling interacts with COX-2 pathway in colonic fibroblasts

(2012) Yingting Zhu et al.   EXPERIMENTAL CELL RESEARCH

Hypoglycemic effects of cocoa (Theobroma cacao L.) autolysates

(2012) Bahareh Sarmadi et al.   FOOD CHEMISTRY

Peracetylated (−)-Epigallocatechin-3-gallate (AcEGCG) Potently Suppresses Dextran Sulfate Sodium-Induced Colitis and Colon Tumorigenesis in Mice

(2012) Yi-Shiou Chiou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo

(2012) Yu-Ting Cheng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply

(2011) Susanne Krehl et al.   CARCINOGENESIS

Inhibitory effects of cocoa tea (Camellia ptilophylla) in human hepatocellular carcinoma HepG2 in vitro and in vivo through apoptosis

(2011) Xiao-rong Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cocoa-rich diet prevents azoxymethane-induced colonic preneoplastic lesions in rats by restraining oxidative stress and cell proliferation and inducing apoptosis

(2011) Ildefonso Rodríguez-Ramiro et al.   MOLECULAR NUTRITION & FOOD RESEARCH

2,3′,4,4′,5′-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice

(2010) Haitao Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Enhand secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina ropria monouclear cells from patients with ulcretive cilitis and Crohn's disease

(2010) H.-C. REINECKER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells

(2010) Ildefonso Rodríguez-Ramiro et al.   EUROPEAN JOURNAL OF NUTRITION

In Vitro and In Vivo Effects of Water Extract of White Cocoa Tea (Camellia ptilophylla) Against Human Prostate Cancer

(2010) Li Peng et al.   PHARMACEUTICAL RESEARCH

Inhibition of inflammatory mediators by polyphenolic plant extracts in human intestinal Caco-2 cells

(2009) Béatrice Romier-Crouzet et al.   FOOD AND CHEMICAL TOXICOLOGY

Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/ β-catenin pathway

(2009) Pandurangan Ashokkumar et al.   INVESTIGATIONAL NEW DRUGS

Cocoa flavonoids up-regulate antioxidant enzyme activity via the ERK1/2 pathway to protect against oxidative stress-induced apoptosis in HepG2 cells☆

(2009) María Ángeles Martín et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

Protective role of luteolin on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis

(2008) Pandurangan Ashokkumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Protection of Human HepG2 Cells against Oxidative Stress by Cocoa Phenolic Extract

(2008) María Angeles Martín et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways

(2008) Sonia Ramos   MOLECULAR NUTRITION & FOOD RESEARCH

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA