G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes

GPCR signaling along the endocytic pathway

(2014) Roshanak Irannejad et al.   CURRENT OPINION IN CELL BIOLOGY

Control Systems of Membrane Transport at the Interface between the Endoplasmic Reticulum and the Golgi

(2014) Jorge Cancino et al.   DEVELOPMENTAL CELL

Visualization of arrestin recruitment by a G-protein-coupled receptor

(2014) Arun K. Shukla et al.   NATURE

Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis

(2014) Nikoleta G Tsvetanova et al.   Nature Chemical Biology

Gαs regulates the post-endocytic sorting of G protein-coupled receptors

(2014) Stéphanie Rosciglione et al.   Nature Communications

Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism

(2013) Congcong He et al.   CELL

Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

(2013) Timothy N. Feinstein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Receptor signals come in waves

(2013) Martin J. Lohse et al.   NATURE

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

Reprogramming of G protein-coupled receptor recycling and signaling by a kinase switch

(2013) R. Vistein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncanonical GPCR signaling arising from a PTH receptor–arrestin–Gβγ complex

(2013) Vanessa L. Wehbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ESCRT machinery

(2012) Oliver Schmidt et al.   CURRENT BIOLOGY

Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking

(2012) Sang-Oh Han et al.   EMBO REPORTS

The retromer complex - endosomal protein recycling and beyond

(2012) M. N. J. Seaman   JOURNAL OF CELL SCIENCE

Differential Association of Receptor-G   Complexes with  -Arrestin2 Determines Recycling Bias and Potential for Tolerance of Delta Opioid Receptor Agonists

(2012) N. Audet et al.   JOURNAL OF NEUROSCIENCE

Non-canonical signaling of the PTH receptor

(2012) Jean-Pierre Vilardaga et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Nanobody stabilization of G protein-coupled receptor conformational states

(2011) Jan Steyaert et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei

(2011) V. L. Koumandou et al.   JOURNAL OF CELL SCIENCE

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

Retromer terminates the generation of cAMP by internalized PTH receptors

(2011) Timothy N Feinstein et al.   Nature Chemical Biology

Endocytosis Promotes Rapid Dopaminergic Signaling

(2011) Sarah J. Kotowski et al.   NEURON

Activation mechanism of the  2-adrenergic receptor

(2011) R. O. Dror et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural flexibility of the G s  -helical domain in the  2-adrenoceptor Gs complex

(2011) G. H. Westfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Phosphorylation Sites on the  2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of  -Arrestin

(2011) K. N. Nobles et al.   Science Signaling

β-arrestin-mediated receptor trafficking and signal transduction

(2011) Sudha K. Shenoy et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil BacteriumBeggiatoa

(2010) Manuela Stierl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arrestin-2 Interacts with the Endosomal Sorting Complex Required for Transport Machinery to Modulate Endosomal Sorting of CXCR4

(2010) Rohit Malik et al.   MOLECULAR BIOLOGY OF THE CELL

Dysbindin Promotes the Post-Endocytic Sorting of G Protein-Coupled Receptors to Lysosomes

(2010) Aaron Marley et al.   PLoS One

Cargo-Mediated Regulation of a Rapid Rab4-Dependent Recycling Pathway

(2009) Guillermo A. Yudowski et al.   MOLECULAR BIOLOGY OF THE CELL

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

(2009) Sébastien Ferrandon et al.   Nature Chemical Biology

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

(2009) Florian Mullershausen et al.   Nature Chemical Biology

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

Alternative Splicing Determines the Post-endocytic Sorting Fate of G-protein-coupled Receptors

(2008) Michael Tanowitz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY