Conformational biosensors reveal GPCR signalling from endosomes

Persistent cAMP signaling by internalized TSH receptors occurs in thyroid but not in HEK293 cells

(2012) Ruth C. Werthmann et al.   FASEB JOURNAL

Nanobody stabilization of G protein-coupled receptor conformational states

(2011) Jan Steyaert et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Dynamin Inhibition Blocks Botulinum Neurotoxin Type A Endocytosis in Neurons and Delays Botulism

(2011) Callista B. Harper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Retromer terminates the generation of cAMP by internalized PTH receptors

(2011) Timothy N Feinstein et al.   Nature Chemical Biology

Endocytosis Promotes Rapid Dopaminergic Signaling

(2011) Sarah J. Kotowski et al.   NEURON

Structural flexibility of the G s  -helical domain in the  2-adrenoceptor Gs complex

(2011) G. H. Westfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

(2010) Benjamin E.L. Lauffer et al.   JOURNAL OF CELL BIOLOGY

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

(2010) Mark T. Howes et al.   JOURNAL OF CELL BIOLOGY

Imaging of persistent cAMP signaling by internalized G protein-coupled receptors

(2010) Davide Calebiro et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Purification and Functional Reconstitution of Monomeric μ-Opioid Receptors

(2009) Adam J. Kuszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cargo-Mediated Regulation of a Rapid Rab4-Dependent Recycling Pathway

(2009) Guillermo A. Yudowski et al.   MOLECULAR BIOLOGY OF THE CELL

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

(2009) Sébastien Ferrandon et al.   Nature Chemical Biology

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

(2009) Florian Mullershausen et al.   Nature Chemical Biology

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endosomes: A legitimate platform for the signaling train

(2009) J. E. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

Determining kinetics and affinities of protein interactions using a parallel real-time label-free biosensor, the Octet

(2008) Yasmina Abdiche et al.   ANALYTICAL BIOCHEMISTRY