Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d

PP2A inhibition results in hepatic insulin resistance despite Akt2 activation

(2016) Thomas Galbo et al.   Aging-US

Insulin inhibits AMPK activity and phosphorylates AMPK Ser485/491 through Akt in hepatocytes, myotubes and incubated rat skeletal muscle

(2014) Rudy J. Valentine et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

PP2A–AMPKα–HSF1 axis regulates the metal-inducible expression of HSPs and ROS clearance

(2014) Xiao-nian Zhu et al.   CELLULAR SIGNALLING

Metformin Pharmacogenomics: Current Status and Future Directions

(2014) A. C. Pawlyk et al.   DIABETES

Protein Phosphatase 2A (PP2A) Regulates Low Density Lipoprotein Uptake through Regulating Sterol Response Element-binding Protein-2 (SREBP-2) DNA Binding

(2014) Lyndi M. Rice et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Molecule Adenosine 5′-Monophosphate Activated Protein Kinase (AMPK) Modulators and Human Diseases

(2014) Sandeep Rana et al.   JOURNAL OF MEDICINAL CHEMISTRY

AMPK activity is regulated by calcium-mediated protein phosphatase 2A activity

(2013) S. Park et al.   CELL CALCIUM

Chemoproteomic Analysis of Intertissue and Interspecies Isoform Diversity of AMP-activated Protein Kinase (AMPK)

(2013) Jiang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conserved regulatory elements in AMPK

(2013) Lei Chen et al.   NATURE

Structural basis of AMPK regulation by small molecule activators

(2013) Bing Xiao et al.   Nature Communications

AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

(2012) D. Grahame Hardie et al.   CHEMISTRY & BIOLOGY

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells

(2011) Zeqin Lian et al.   Lipids in Health and Disease

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

AMP-activated protein kinase: nature's energy sensor

(2011) David Carling et al.   Nature Chemical Biology

Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism

(2011) Thomas Galbo et al.   PLoS One

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMP-activated protein kinase: also regulated by ADP?

(2011) D. Grahame Hardie et al.   TRENDS IN BIOCHEMICAL SCIENCES

Fatty acid regulation of hepatic lipid metabolism

(2010) Donald B Jump   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

B56α/Protein Phosphatase 2A Inhibits Adipose Lipolysis in High-Fat Diet-Induced Obese Mice

(2010) Brice P. Kinney et al.   ENDOCRINOLOGY

The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 β cells

(2010) Luisa Garcia-Haro et al.   FASEB JOURNAL

PP2A Mediated AMPK Inhibition Promotes HSP70 Expression in Heat Shock Response

(2010) Ting Wang et al.   PLoS One

AMPK: Lessons from transgenic and knockout animals

(2009) Benoit Viollet   Frontiers in Bioscience-Landmark

The role of AMP-activated protein kinase in the cardiovascular system

(2009) Daisuke Nagata et al.   HYPERTENSION RESEARCH

Structural insight into the autoinhibition mechanism of AMP-activated protein kinase

(2009) Lei Chen et al.   NATURE

Protein phosphatase 2A regulatory subunits and cancer

(2008) Pieter J.A. Eichhorn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism

(2008) C. A. Witczak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

(2008) H. Boon et al.   DIABETOLOGIA

High-fat Diet Alters PP2A, TC10, and CIP4 Expression in Visceral Adipose Tissue of Rats

(2008) Hye-Seung Jun et al.   Obesity