Metformin Pharmacogenomics: Current Status and Future Directions

The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World Implementation

(2013) A R Shuldiner et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Standards of Medical Care in Diabetes--2014

(2013)   DIABETES CARE

Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology Consensus Panel on Type 2 Diabetes Mellitus: An Algorithm for Glycemic Control

(2013) Helena Rodbard et al.   Endocrine Practice

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

(2013) Russell A. Miller et al.   NATURE

The potential impact of pharmacogenetic testing on medication adherence

(2013) S B Haga et al.   PHARMACOGENOMICS JOURNAL

Childhood obesity and type 2 diabetes: the frightening epidemic

(2013) Nicola Santoro   World Journal of Pediatrics

The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin

(2012) S L Stocker et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Adoption of Pharmacogenomic Testing by US Physicians: Results of a Nationwide Survey

(2012) E J Stanek et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The C Allele of ATM rs11212617 Does Not Associate With Metformin Response in the Diabetes Prevention Program

(2012) J. C. Florez et al.   DIABETES CARE

Long-Term Safety, Tolerability, and Weight Loss Associated With Metformin in the Diabetes Prevention Program Outcomes Study

(2012)   DIABETES CARE

Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach: Position Statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

(2012) S. E. Inzucchi et al.   DIABETES CARE

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts

(2012) N. van Leeuwen et al.   DIABETOLOGIA

To the Editor

(2012) Angela Woods et al.   NATURE GENETICS

The role of ATM in response to metformin treatment and activation of AMPK

(2012) Sook Wah Yee et al.   NATURE GENETICS

A Clinical Trial to Maintain Glycemic Control in Youth with Type 2 Diabetes

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Metformin pathways

(2012) Li Gong et al.   Pharmacogenetics and Genomics

Research Highlights: Highlights from the latest articles in pharmacogenomics of oral antidiabetic drugs

(2012) Ivan Tkáč   PHARMACOGENOMICS

Disposition of metformin: Variability due to polymorphisms of organic cation transporters

(2011) Oliver Zolk   ANNALS OF MEDICINE

Serine racemase rs391300 G/A polymorphism influences the therapeutic efficacy of metformin in Chinese patients with diabetes mellitus type 2

(2011) Min Dong et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

A Common 5′-UTR Variant in MATE2-K Is Associated With Poor Response to Metformin

(2011) J H Choi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

(2011) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network

(2011) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c

(2011) Mette M.H. Christensen et al.   Pharmacogenetics and Genomics

The Cardiovascular Effects of Metformin: Further Reasons to Consider An Old Drug as a Cornerstone in the Therapy of Type 2 Diabetes Mellitus

(2010) Giovanni Anfossi et al.   Current Vascular Pharmacology

Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program

(2010) K. A. Jablonski et al.   DIABETES

Organic Cation Transporter 1 Polymorphisms Predict the Metabolic Response to Metformin in Women with the Polycystic Ovary Syndrome

(2010) Alessandra Gambineri et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

(2010) Kaixin Zhou et al.   NATURE GENETICS

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin

(2010) Ligong Chen et al.   Pharmacogenetics and Genomics

Pharmacy Benefit Managers, Pharmacies, and Pharmacogenomic Testing: Prescription for Progress?

(2010) E. J. Topol   Science Translational Medicine

The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin

(2009) M V Tzvetkov et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

(2009) M L Becker et al.   PHARMACOGENOMICS JOURNAL

Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

(2008) D. M. Nathan et al.   DIABETES CARE

Impact of Metformin, Oral Contraceptives, and Lifestyle Modification on Polycystic Ovary Syndrome in Obese Adolescent Women: Do We Need a New Drug?

(2008) Richard S. Legro   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Prevention of Diabetes in Women with a History of Gestational Diabetes: Effects of Metformin and Lifestyle Interventions

(2008) Robert E. Ratner et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM