Chemoproteomic Analysis of Intertissue and Interspecies Isoform Diversity of AMP-activated Protein Kinase (AMPK)

Mass Spectrometry Based Method to Increase Throughput for Kinome Analyses Using ATP Probes

(2013) F. E. McAllister et al.   ANALYTICAL CHEMISTRY

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

(2013) Graeme J. Gowans et al.   Cell Metabolism

Subunit composition of AMPK trimers present in the cytokinetic apparatus: Implications for drug target identification

(2012) Katalin Pinter et al.   CELL CYCLE

Chemical proteomics and its impact on the drug discovery process

(2012) Qing Miao et al.   Expert Review of Proteomics

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity

(2012) Anke Van Summeren et al.   TOXICOLOGY IN VITRO

In Situ Kinase Profiling Reveals Functionally Relevant Properties of Native Kinases

(2011) Matthew P. Patricelli et al.   CHEMISTRY & BIOLOGY

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

(2011) X. Stephenne et al.   DIABETOLOGIA

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Proteomic Analysis of Colon Tissue from Interleukin-10 Gene-Deficient Mice Fed Polyunsaturated Fatty Acids with Comparison to Transcriptomic Analysis

(2011) Janine M. Cooney et al.   JOURNAL OF PROTEOME RESEARCH

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

Less label, more free: Approaches in label-free quantitative mass spectrometry

(2011) Karlie A. Neilson et al.   PROTEOMICS

AMP-activated protein kinase: also regulated by ADP?

(2011) D. Grahame Hardie et al.   TRENDS IN BIOCHEMICAL SCIENCES

Proteomics accelerating the identification of the target molecule of bioactive small molecules

(2010) Konstanty Wierzba et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Metformin action on AMP-activated protein kinase: a translational research approach to understanding a potential new therapeutic target

(2010) J. G. Boyle et al.   DIABETIC MEDICINE

Workflow Comparison for Label-Free, Quantitative Secretome Proteomics for Cancer Biomarker Discovery: Method Evaluation, Differential Analysis, and Verification in Serum

(2010) Sander R. Piersma et al.   JOURNAL OF PROTEOME RESEARCH

Quantitation of Soybean Allergens Using Tandem Mass Spectrometry

(2010) Norma L. Houston et al.   JOURNAL OF PROTEOME RESEARCH

Relative, label-free protein quantitation: Spectral counting error statistics from nine replicate MudPIT samples

(2010) Bret Cooper et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

siRNA-mediated AMPKα1 subunit gene PRKAA1 silencing enhances methylmercury toxicity in HEK293 cells

(2010) Gi-Wook Hwang et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Highly Reproducible Label Free Quantitative Proteomic Analysis of RNA Polymerase Complexes

(2010) Amber L. Mosley et al.   MOLECULAR & CELLULAR PROTEOMICS

 -Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

(2010) J. S. Oakhill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Escherichia coli expression, purification and characterization of functional full-length recombinant α2β2γ3 heterotrimeric complex of human AMP-activated protein kinase

(2010) Francis Rajamohan et al.   PROTEIN EXPRESSION AND PURIFICATION

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives

(2009) B. Viollet et al.   Acta Physiologica

Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer

(2009) S. Fogarty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

(2008) Benjamin F. Cravatt et al.   Annual Review of Biochemistry

The APEX Quantitative Proteomics Tool: Generating protein quantitation estimates from LC-MS/MS proteomics results

(2008) John C Braisted et al.   BMC BIOINFORMATICS

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

(2008) John W. Scott et al.   CHEMISTRY & BIOLOGY

Evaluation of confidence and reproducibility in quantitative proteomics performed by a capillary isoelectric focusing-based proteomic platform coupled with a spectral counting approach

(2008) Brian M. Balgley et al.   ELECTROPHORESIS

Small Molecule Antagonizes Autoinhibition and Activates AMP-activated Protein Kinase in Cells

(2008) Tao Pang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY