Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis

Resolution of inflammation is altered in Alzheimer's disease

(2015) Xiuzhe Wang et al.   Alzheimers & Dementia

Resolvins Attenuate Inflammation and Promote Resolution in Cigarette Smoke-Exposed Human Macrophages

(2015) Amanda Croasdell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

ω-3 Supplementation increases amyloid-β phagocytosis and resolvin D1 in patients with minor cognitive impairment

(2015) Milan Fiala et al.   FASEB JOURNAL

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

Effects of n-3 FA supplementation on the release of proresolving lipid mediators by blood mononuclear cells: the OmegAD study

(2015) Xiuzhe Wang et al.   JOURNAL OF LIPID RESEARCH

Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages

(2015) S. Rossi et al.   MEDIATORS OF INFLAMMATION

The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution

(2015) Charles N. Serhan et al.   SEMINARS IN IMMUNOLOGY

Pivotal role of choline metabolites in remyelination

(2014) Thomas Skripuletz et al.   BRAIN

Immunoresolving actions of oral resolvin D1 include selective regulation of the transcription machinery in resolution-phase mouse macrophages

(2014) Antonio Recchiuti et al.   FASEB JOURNAL

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Protective Actions of Aspirin-Triggered (17R) Resolvin D1 and Its Analogue, 17R-Hydroxy-19-Para-Fluorophenoxy-Resolvin D1 Methyl Ester, in C5a-Dependent IgG Immune Complex–Induced Inflammation and Lung Injury

(2014) Huifang Tang et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells

(2014) Longyan Li et al.   Journal of Neuroinflammation

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation

(2014) Lior Mayo et al.   NATURE MEDICINE

n-3 PUFA supplementation benefits microglial responses to myelin pathology

(2014) Songela Chen et al.   Scientific Reports

Kynurenines in CNS disease: regulation by inflammatory cytokines

(2014) Brian M. Campbell et al.   Frontiers in Neuroscience

Potential of Urinary Metabolites for Diagnosing Multiple Sclerosis

(2013) Teklab Gebregiworgis et al.   ACS Chemical Biology

Recent advances in metabolomics in neurological disease, and future perspectives

(2013) Ai-hua Zhang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders

(2013) Trevor W Stone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

(2013) Matthew Spite et al.   Cell Metabolism

Disease-modifying therapy in multiple sclerosis and chronic inflammatory demyelinating polyradiculoneuropathy: common and divergent current and future strategies

(2013) N. Melzer et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Resolvin D1 improves survival in experimental sepsis through reducing bacterial load and preventing excessive activation of inflammatory response

(2013) F. Chen et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Resolvin D1 primes the resolution process initiated by calorie restriction in obesity-induced steatohepatitis

(2013) Bibiana Rius et al.   FASEB JOURNAL

Association of fish consumption and omega 3 supplementation with quality of life, disability and disease activity in an international cohort of people with multiple sclerosis

(2013) George A. Jelinek et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition

(2013) Hennariikka Koivisto et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cerebral Biochemical Pathways in Experimental Autoimmune Encephalomyelitis and Adjuvant Arthritis: A Comparative Metabolomic Study

(2013) Norbert W. Lutz et al.   PLoS One

A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation

(2013) Hsi-Min Hsiao et al.   PLoS One

Novel n-3 Immunoresolvents: Structures and Actions

(2013) Jesmond Dalli et al.   Scientific Reports

ω-3 Fatty Acid Treatment in Multiple Sclerosis (OFAMS Study)

(2012) Øivind Torkildsen et al.   ARCHIVES OF NEUROLOGY

Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

(2012) R. Parsa et al.   DIABETES

First-Line Disease-Modifying Therapies in Paediatric Multiple Sclerosis

(2012) Jessica Johnston et al.   DRUGS

Myeloid-derived suppressor cells in transplantation and cancer

(2012) Jordi C. Ochando et al.   IMMUNOLOGIC RESEARCH

Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses

(2012) A. P. Rogerio et al.   JOURNAL OF IMMUNOLOGY

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

(2012) J. Xia et al.   NUCLEIC ACIDS RESEARCH

Laquinimod, a Quinoline-3-Carboxamide, Induces Type II Myeloid Cells That Modulate Central Nervous System Autoimmunity

(2012) Ulf Schulze-Topphoff et al.   PLoS One

Defects in Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial Alzheimer's Disease

(2012) Eugenia Trushina et al.   PLoS One

Identification of Naturally Occurring Fatty Acids of the Myelin Sheath That Resolve Neuroinflammation

(2012) P. P. Ho et al.   Science Translational Medicine

The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats

(2011) JF Lima-Garcia et al.   BRITISH JOURNAL OF PHARMACOLOGY

Proteomics-Based Technologies in the Discovery of Biomarkers for Multiple Sclerosis in the Cerebrospinal Fluid

(2011) A. S.T. Lourenco et al.   CURRENT MOLECULAR MEDICINE

Challenges and opportunities of metabolomics

(2011) Caroline H. Johnson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

(2011) Esther Titos et al.   JOURNAL OF IMMUNOLOGY

Omega-3 Fatty Acid-Derived Mediators 17(R)-Hydroxy Docosahexaenoic Acid, Aspirin-Triggered Resolvin D1 and Resolvin D2 Prevent Experimental Colitis in Mice

(2011) A. F. Bento et al.   JOURNAL OF IMMUNOLOGY

Identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology

(2011) Yoshiaki Sato et al.   JOURNAL OF LIPID RESEARCH

Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis

(2011) Marek J. Noga et al.   Metabolomics

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

n–3 Fatty Acids in Cardiovascular Disease

(2011) Raffaele De Caterina   NEW ENGLAND JOURNAL OF MEDICINE

Resolvins as Regulators of the Immune System

(2011) Hiroyuki Seki et al.   TheScientificWorldJOURNAL

The role of metabolites and metabolomics in clinically applicable biomarkers of disease

(2010) Mamas Mamas et al.   ARCHIVES OF TOXICOLOGY

Docosahexaenoic acid prevents dendritic cell maturation, inhibits antigen-specific Th1/Th17 differentiation and suppresses experimental autoimmune encephalomyelitis

(2010) Weimin Kong et al.   BRAIN BEHAVIOR AND IMMUNITY

LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery

(2010) Lin Lin et al.   JOURNAL OF PROTEOME RESEARCH

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

(2010) J. W. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organization of GC/MS and LC/MS metabolomics data into chemical libraries

(2010) Corey D DeHaven et al.   Journal of Cheminformatics

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity

(2009) Narender Nath et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress

(2009) M Spite et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis

(2009) N. Nath et al.   JOURNAL OF IMMUNOLOGY

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

(2009) J. Xia et al.   NUCLEIC ACIDS RESEARCH

Metabolomic Profiling in LRRK2-Related Parkinson's Disease

(2009) Krisztina K. Johansen et al.   PLoS One

Discovery of Metabolomics Biomarkers for Early Detection of Nephrotoxicity

(2009) Kurt J. Boudonck et al.   TOXICOLOGIC PATHOLOGY

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

(2008) Naoki Umemura et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Systems biology: Metabonomics

(2008) Jeremy K. Nicholson et al.   NATURE

Analysis of the adult human plasma metabolome

(2008) Kay A Lawton et al.   PHARMACOGENOMICS