Structural Mechanism of the Interaction of Alzheimer Disease Aβ Fibrils with the Non-steroidal Anti-inflammatory Drug (NSAID) Sulindac Sulfide
出版年份 2015 全文链接
标题
Structural Mechanism of the Interaction of Alzheimer Disease Aβ Fibrils with the Non-steroidal Anti-inflammatory Drug (NSAID) Sulindac Sulfide
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 48, Pages 28737-28745
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2015-09-29
DOI
10.1074/jbc.m115.675215
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Molecular Structure of Alzheimer β-Amyloid Fibrils Formed in the Presence of Phospholipid Vesicles
- (2014) Zheng Niu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Potent γ-secretase inhibitors/modulators interact with amyloid-β fibrils but do not inhibit fibrillation: A high-resolution NMR study
- (2014) Ravichandran Yesuvadian et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Curcumin Alters the Salt Bridge-containing Turn Region in Amyloid β(1–42) Aggregates
- (2014) Venus Singh Mithu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Characterization and Inhibition of Toxic Amyloid-β Oligomeric Intermediates
- (2013) Ayyalusamy Ramamoorthy et al. BIOPHYSICAL JOURNAL
- Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue
- (2013) Jun-Xia Lu et al. CELL
- Characterization of Intermediate Steps in Amyloid Beta (Aβ) Production under Near-native Conditions
- (2013) Fredrik Olsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Site-specific Inhibitory Mechanism for Amyloid β42 Aggregation by Catechol-type Flavonoids Targeting the Lys Residues
- (2013) Mizuho Sato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Asymmetric Dimer as the Basic Subunit in Alzheimer’s Disease Amyloid β Fibrils
- (2012) Juan Miguel Lopez del Amo et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: Characterization of interaction of NSAIDs with phosphatidylcholine
- (2012) Lenard M. Lichtenberger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment
- (2012) Kirill D. Nadezhdin et al. FEBS LETTERS
- Second Generation γ-Secretase Modulators Exhibit Different Modulation of Notch β and Aβ Production
- (2012) Johanna Wanngren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phenolic Compounds Prevent Amyloid β-Protein Oligomerization and Synaptic Dysfunction by Site-specific Binding
- (2012) Kenjiro Ono et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Properties of EGCG-Induced, Nontoxic Alzheimer's Disease Aβ Oligomers
- (2012) Juan Miguel Lopez del Amo et al. JOURNAL OF MOLECULAR BIOLOGY
- The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol
- (2012) P. J. Barrett et al. SCIENCE
- The Amyloid-Congo Red Interface at Atomic Resolution
- (2011) Anne K. Schütz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins
- (2011) Seong Il Yoo et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A partially folded structure of amyloid-beta(1–40) in an aqueous environment
- (2011) Subramanian Vivekanandan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- NSAID-Based γ-Secretase Modulators Do Not Bind to the Amyloid-β Polypeptide
- (2011) Paul J. Barrett et al. BIOCHEMISTRY
- Solid-state NMR analysis of interaction sites of curcumin and 42-residue amyloid β-protein fibrils
- (2011) Yuichi Masuda et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Bacterial Inclusion Bodies of Alzheimer's Disease β-Amyloid Peptides Can Be Employed To Study Native-Like Aggregation Intermediate States
- (2011) Muralidhar Dasari et al. CHEMBIOCHEM
- Structural properties of so-called NSAID–phospholipid-complexes
- (2011) Jan Hüsch et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- A New Structural Model of Aβ40Fibrils
- (2011) Ivano Bertini et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils
- (2011) Jan Bieschke et al. Nature Chemical Biology
- Interaction between Amyloid Beta Peptide and an Aggregation Blocker Peptide Mimicking Islet Amyloid Polypeptide
- (2011) Nasrollah Rezaei-Ghaleh et al. PLoS One
- The Amyloid Precursor Protein C-Terminal Fragment C100 Occurs in Monomeric and Dimeric Stable Conformations and Binds γ-Secretase Modulators
- (2010) Anne Botev et al. BIOCHEMISTRY
- Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils
- (2010) Mahiuddin Ahmed et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Amyloid beta 42 peptide (A 42)-lowering compounds directly bind to A and interfere with amyloid precursor protein (APP) transmembrane dimerization
- (2010) L. Richter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Design of small molecules that target metal-A species and regulate metal-induced A aggregation and neurotoxicity
- (2010) J.-S. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
- (2010) Jan Bieschke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- What is the role of amyloid precursor protein dimerization?
- (2010) Naouel Ben Khalifa et al. Cell Adhesion & Migration
- Nonspecificity of Binding of γ-Secretase Modulators to the Amyloid Precursor Protein
- (2009) Andrew J. Beel et al. BIOCHEMISTRY
- The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: A physico-chemical study with lecithin phospholipids
- (2009) Marcela Manrique Moreno et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide
- (2009) Dominic M. Walsh et al. FEBS Journal
- TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts
- (2009) Yang Shen et al. JOURNAL OF BIOMOLECULAR NMR
- Role of Amyloid- Glycine 33 in Oligomerization, Toxicity, and Neuronal Plasticity
- (2009) A. Harmeier et al. JOURNAL OF NEUROSCIENCE
- Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
- (2008) Dennis J. Selkoe BEHAVIOURAL BRAIN RESEARCH
- Stoichiometry and Physical Chemistry of Promiscuous Aggregate-Based Inhibitors
- (2008) Kristin E. D. Coan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Substrate-targeting γ-secretase modulators
- (2008) Thomas L. Kukar et al. NATURE
- Small-molecule aggregates inhibit amyloid polymerization
- (2008) Brian Y Feng et al. Nature Chemical Biology
- Voronoia: analyzing packing in protein structures
- (2008) K. Rother et al. NUCLEIC ACIDS RESEARCH
- Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils
- (2008) A. K. Paravastu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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