Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy

Anti-Viral and Anti-Inflammatory Mechanisms of the Innate Immune Transcription Factor Interferon Regulatory Factor 3: Relevance to Human CNS Diseases

(2012) Leonid Tarassishin et al.   Journal of Neuroimmune Pharmacology

Sensing Adenovirus Infection: Activation of Interferon Regulatory Factor 3 in RAW 264.7 Cells

(2012) Saskia C. Stein et al.   JOURNAL OF VIROLOGY

Role of Interferon Regulatory Factor 3-Mediated Apoptosis in the Establishment and Maintenance of Persistent Infection by Sendai Virus

(2012) S. Chattopadhyay et al.   JOURNAL OF VIROLOGY

Emerging Role of Ubiquitination in Antiviral RIG-I Signaling

(2012) J. Maelfait et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart

(2011) Clint L. Miller et al.   BASIC RESEARCH IN CARDIOLOGY

EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy

(2011) Giovanni Esposito et al.   BASIC RESEARCH IN CARDIOLOGY

Chronic akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy

(2011) Yinan Hua et al.   BASIC RESEARCH IN CARDIOLOGY

Tumor necrosis factor receptor 2 signaling limits β-adrenergic receptor-mediated cardiac hypertrophy in vivo

(2011) Jason B. Garlie et al.   BASIC RESEARCH IN CARDIOLOGY

Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction

(2011) Jinfeng Xiao et al.   BASIC RESEARCH IN CARDIOLOGY

Activated NHE1 is required to induce early cardiac hypertrophy in mice

(2011) Fatima Mraiche et al.   BASIC RESEARCH IN CARDIOLOGY

The TIR/BB-loop mimetic AS-1 prevents cardiac hypertrophy by inhibiting IL-1R-mediated MyD88-dependent signaling

(2011) Yun Zhu et al.   BASIC RESEARCH IN CARDIOLOGY

Conditional transgenic expression of TIR-domain-containing adaptor-inducing interferon-β (TRIF) in the adult mouse heart is protective in acute viral myocarditis

(2011) Zhaohui Xu et al.   BASIC RESEARCH IN CARDIOLOGY

Desmoglein 2 mutant mice develop cardiac fibrosis and dilation

(2011) Claudia A. Krusche et al.   BASIC RESEARCH IN CARDIOLOGY

The coronary circulation in cardioprotection: more than just one confounder

(2011) G. Heusch et al.   CARDIOVASCULAR RESEARCH

IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension

(2011) Kensuke Tsushima et al.   FASEB JOURNAL

A Radical View on the Contractile Machinery in Human Heart Failure⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

(2011) Gerd Heusch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The IRF-3/Bax-Mediated Apoptotic Pathway, Activated by Viral Cytoplasmic RNA and DNA, Inhibits Virus Replication

(2011) S. Chattopadhyay et al.   JOURNAL OF VIROLOGY

SCIPIO brings new momentum to cardiac cell therapy

(2011) Gerd Heusch   LANCET

Suppression of IRF4 by IRF1, 3, and 7 in Noxa Expression Is a Necessary Event for IFN- -Mediated Tumor Elimination

(2011) S. Piya et al.   MOLECULAR CANCER RESEARCH

Activating Transcription Factor 3 Deficiency Promotes Cardiac Hypertrophy, Dysfunction, and Fibrosis Induced by Pressure Overload

(2011) Heng Zhou et al.   PLoS One

TGF-β1 improves cardiac performance via up-regulation of laminin receptor 37/67 in adult ventricular cardiomyocytes

(2010) Sibylle Wenzel et al.   BASIC RESEARCH IN CARDIOLOGY

Tetrandrine blocks cardiac hypertrophy by disrupting reactive oxygen species-dependent ERK1/2 signalling

(2010) Di-Fei Shen et al.   BRITISH JOURNAL OF PHARMACOLOGY

The contribution of reactive oxygen species and p38 mitogen-activated protein kinase to myofilament oxidation and progression of heart failure in rabbits

(2010) P Heusch et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of immunity and oncogenesis by the IRF transcription factor family

(2010) David Savitsky et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Varicella-Zoster Virus Immediate-Early Protein 62 Blocks Interferon Regulatory Factor 3 (IRF3) Phosphorylation at Key Serine Residues: a Novel Mechanism of IRF3 Inhibition among Herpesviruses

(2010) N. Sen et al.   JOURNAL OF VIROLOGY

Diastolic heart failure: a misNOmer

(2009) Gerd Heusch   BASIC RESEARCH IN CARDIOLOGY

Conserved Herpesviral Kinase Promotes Viral Persistence by Inhibiting the IRF-3-Mediated Type I Interferon Response

(2009) Seungmin Hwang et al.   Cell Host & Microbe

LIM and Cysteine-Rich Domains 1 Regulates Cardiac Hypertrophy by Targeting Calcineurin/Nuclear Factor of Activated T Cells Signaling

(2009) Zhou-Yan Bian et al.   HYPERTENSION

Carbon Monoxide Inhibits TLR-Induced Dendritic Cell Immunogenicity

(2009) S. Remy et al.   JOURNAL OF IMMUNOLOGY

Interferon regulatory factor family of transcription factors and regulation of oncogenesis

(2008) Akinori Takaoka et al.   CANCER SCIENCE

Cellular repressor of E1A-stimulated genes attenuates cardiac hypertrophy and fibrosis

(2008) Zhouyan Bian et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway

(2008) Jun Cai et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice

(2008) Yuri Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3β signaling

(2008) Qizhu Tang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

(2008) Kristina Lorenz et al.   NATURE MEDICINE