标题
Emerging Role of Ubiquitination in Antiviral RIG-I Signaling
作者
关键词
-
出版物
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
Volume 76, Issue 1, Pages 33-45
出版商
American Society for Microbiology
发表日期
2012-03-06
DOI
10.1128/mmbr.05012-11
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN- Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3
- (2014) R. Higgs et al. JOURNAL OF IMMUNOLOGY
- Linear ubiquitination in NF-κB signaling and inflammation: What we do understand and what we do not
- (2011) Kelly Verhelst et al. BIOCHEMICAL PHARMACOLOGY
- Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis
- (2011) S Lippens et al. CELL DEATH AND DIFFERENTIATION
- A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response
- (2011) Suzanne Paz et al. CELL RESEARCH
- A loss-of-function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients
- (2011) Julien Pothlichet et al. EMBO Molecular Medicine
- The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity
- (2011) Mirjam Kool et al. IMMUNITY
- RIG-I RNA Helicase Activation of IRF3 Transcription Factor Is Negatively Regulated by Caspase-8-Mediated Cleavage of the RIP1 Protein
- (2011) Akhil Rajput et al. IMMUNITY
- DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells
- (2011) Zhiqiang Zhang et al. IMMUNITY
- ABIN1 Protein Cooperates with TAX1BP1 and A20 Proteins to Inhibit Antiviral Signaling
- (2011) Linlin Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction
- (2011) Kyung-Soo Inn et al. MOLECULAR CELL
- SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
- (2011) Fuminori Tokunaga et al. NATURE
- SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
- (2011) Fumiyo Ikeda et al. NATURE
- Linear ubiquitination prevents inflammation and regulates immune signalling
- (2011) Björn Gerlach et al. NATURE
- A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
- (2011) Mourad Matmati et al. NATURE GENETICS
- Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
- (2011) Roland Züst et al. NATURE IMMUNOLOGY
- Modulation of NF-κB signalling by microbial pathogens
- (2011) Masmudur M. Rahman et al. NATURE REVIEWS MICROBIOLOGY
- The spatial and temporal organization of ubiquitin networks
- (2011) Caroline Grabbe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Expression, biological activities and mechanisms of action of A20 (TNFAIP3)
- (2010) Lynn Verstrepen et al. BIOCHEMICAL PHARMACOLOGY
- What Determines the Specificity and Outcomes of Ubiquitin Signaling?
- (2010) Fumiyo Ikeda et al. CELL
- Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity
- (2010) Evelyn Dixit et al. CELL
- Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity
- (2010) Wenwen Zeng et al. CELL
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- Ubiquitin: Same Molecule, Different Degradation Pathways
- (2010) Michael J. Clague et al. CELL
- The Ubiquitin Ligase Riplet Is Essential for RIG-I-Dependent Innate Immune Responses to RNA Virus Infection
- (2010) Hiroyuki Oshiumi et al. Cell Host & Microbe
- Expanding role of ubiquitination in NF-κB signaling
- (2010) Siqi Liu et al. CELL RESEARCH
- Deubiquitinases in the regulation of NF-κB signaling
- (2010) Edward W Harhaj et al. CELL RESEARCH
- Non-canonical NF-κB signaling pathway
- (2010) Shao-Cong Sun CELL RESEARCH
- Sensing and Signaling in Antiviral Innate Immunity
- (2010) Luke A.J. O'Neill et al. CURRENT BIOLOGY
- Tripartite-motif proteins and innate immune regulation
- (2010) Finlay W McNab et al. CURRENT OPINION IN IMMUNOLOGY
- Viral hijacking of the host ubiquitin system to evade interferon responses
- (2010) Kasinath Viswanathan et al. CURRENT OPINION IN MICROBIOLOGY
- The ubiquitous role of ubiquitin in the DNA damage response
- (2010) Abdallah Al-Hakim et al. DNA REPAIR
- The Ubiquitin E3 Ligase RAUL Negatively Regulates Type I Interferon through Ubiquitination of the Transcription Factors IRF7 and IRF3
- (2010) Yanxing Yu et al. IMMUNITY
- Ubiquitin Makes Its Mark on Immune Regulation
- (2010) Barbara A. Malynn et al. IMMUNITY
- Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis
- (2010) Rebeca Pérez de Diego et al. IMMUNITY
- Intracellular Toll-like Receptors
- (2010) Amanda L. Blasius et al. IMMUNITY
- Virus-triggered Ubiquitination of TRAF3/6 by cIAP1/2 Is Essential for Induction of Interferon-β (IFN-β) and Cellular Antiviral Response
- (2010) Ai-Ping Mao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases
- (2010) Kislay Parvatiyar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fas-associated Death Domain (FADD) and the E3 Ubiquitin-Protein Ligase TRIM21 Interact to Negatively Regulate Virus-induced Interferon Production
- (2010) Jennifer A. Young et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Role for the Human Nucleotide-binding Domain, Leucine-rich Repeat-containing Family Member NLRC5 in Antiviral Responses
- (2010) Andreas Neerincx et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis
- (2010) Lars Vereecke et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9–driven antiinflammatory cytokine production
- (2010) Jose M. González-Navajas et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Thymocyte-Specific Truncation of the Deubiquitinating Domain of CYLD Impairs Positive Selection in a NF- B Essential Modulator-Dependent Manner
- (2010) A. Tsagaratou et al. JOURNAL OF IMMUNOLOGY
- Retinoic Acid-Inducible Gene-I-Like Receptors
- (2010) Kazuhide Onoguchi et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Possible association of VISA gene polymorphisms with susceptibility to systemic lupus erythematosus in Chinese population
- (2010) Xiaowen Liu et al. MOLECULAR BIOLOGY REPORTS
- Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
- (2010) Shinichiro Nakada et al. NATURE
- 2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
- (2010) Stephane Daffis et al. NATURE
- Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
- (2010) Lynn Bedford et al. NATURE REVIEWS DRUG DISCOVERY
- Emerging roles for the non-canonical IKKs in cancer
- (2010) R R Shen et al. ONCOGENE
- TRAF5 Is a Downstream Target of MAVS in Antiviral Innate Immune Signaling
- (2010) Eric D. Tang et al. PLoS One
- Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors
- (2010) Rowan Higgs et al. PLoS One
- Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense
- (2010) K.-i. Arimoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains
- (2010) Shengkai Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
- (2010) T. Satoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes
- (2010) N. Shembade et al. SCIENCE
- TRIM Proteins: Another Class of Viral Victims
- (2010) M. Munir Science Signaling
- Ubiquitin chain cleavage: CYLD at work
- (2010) Ramin Massoumi TRENDS IN BIOCHEMICAL SCIENCES
- The Role of Ubiquitin in NF-κB Regulatory Pathways
- (2009) Brian Skaug et al. Annual Review of Biochemistry
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I
- (2009) Michaela Ulrike Gack et al. Cell Host & Microbe
- The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-κB signalling
- (2009) Noula Shembade et al. EMBO JOURNAL
- Phosphorylation of NF-κB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination
- (2009) Hui Geng et al. EMBO REPORTS
- Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus
- (2009) Martin Schlee et al. IMMUNITY
- The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA
- (2009) Bo Zhong et al. IMMUNITY
- Regulation of Endoplasmic Reticulum-associated Degradation by RNF5-dependent Ubiquitination of JNK-associated Membrane Protein (JAMP)
- (2009) Marianna Tcherpakov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Virus-triggered Signaling by OTUB1- and OTUB2-mediated Deubiquitination of TRAF3 and TRAF6
- (2009) Shu Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells
- (2009) Susie S. Mikkelsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Loss of Function Mutations in Human Genes Encoding RIG-I and MDA5
- (2009) Taeko Shigemoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vicious circle: systemic autoreactivity in Ro52/TRIM21-deficient mice: Figure 1.
- (2009) Silvia Bolland et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway
- (2009) Alexander Espinosa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MAVS Self-Association Mediates Antiviral Innate Immune Signaling
- (2009) E. D. Tang et al. JOURNAL OF VIROLOGY
- Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection
- (2009) A. Pichlmair et al. JOURNAL OF VIROLOGY
- A Ubiquitin Replacement Strategy in Human Cells Reveals Distinct Mechanisms of IKK Activation by TNFα and IL-1β
- (2009) Ming Xu et al. MOLECULAR CELL
- Key Role of Ubc5 and Lysine-63 Polyubiquitination in Viral Activation of IRF3
- (2009) Wenwen Zeng et al. MOLECULAR CELL
- Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
- (2009) Tobias L. Haas et al. MOLECULAR CELL
- Direct activation of protein kinases by unanchored polyubiquitin chains
- (2009) Zong-Ping Xia et al. NATURE
- Ubiquitylation in innate and adaptive immunity
- (2009) Vijay G. Bhoj et al. NATURE
- Involvement of linear polyubiquitylation of NEMO in NF-κB activation
- (2009) Fuminori Tokunaga et al. NATURE CELL BIOLOGY
- Viral avoidance and exploitation of the ubiquitin system
- (2009) Felix Randow et al. NATURE CELL BIOLOGY
- Activation of innate immune antiviral responses by Nod2
- (2009) Ahmed Sabbah et al. NATURE IMMUNOLOGY
- Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines
- (2009) Ping-Hui Tseng et al. NATURE IMMUNOLOGY
- PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4
- (2009) Fuping You et al. NATURE IMMUNOLOGY
- Building ubiquitin chains: E2 enzymes at work
- (2009) Yihong Ye et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Physiological functions of the HECT family of ubiquitin ligases
- (2009) Daniela Rotin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- REUL Is a Novel E3 Ubiquitin Ligase and Stimulator of Retinoic-Acid-Inducible Gene-I
- (2009) Dong Gao et al. PLoS One
- TRAF6 Establishes Innate Immune Responses by Activating NF-κB and IRF7 upon Sensing Cytosolic Viral RNA and DNA
- (2009) Hiroyasu Konno et al. PLoS One
- 5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
- (2009) A. Schmidt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RIG-I-like receptors: Sensing and responding to RNA virus infection
- (2009) Peyman Nakhaei et al. SEMINARS IN IMMUNOLOGY
- The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology
- (2009) Lars Vereecke et al. TRENDS IN IMMUNOLOGY
- Signaling to NF- B: Regulation by Ubiquitination
- (2009) I. E. Wertz et al. Cold Spring Harbor Perspectives in Biology
- The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation
- (2009) Peyman Nakhaei et al. PLoS Pathogens
- Protein partners of deubiquitinating enzymes
- (2008) Karen H. Ventii et al. BIOCHEMICAL JOURNAL
- T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain
- (2008) Ana Lucia Giannini et al. BIOCHEMICAL JOURNAL
- Structural basis and specificity of human otubain 1-mediated deubiquitination
- (2008) Mariola J. Edelmann et al. BIOCHEMICAL JOURNAL
- Itch-/- and T cells independently contribute to autoimmunity in Itchy mice
- (2008) V. Parravicini et al. BLOOD
- Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3
- (2008) Min Zhang et al. CELL RESEARCH
- The enhanceosome
- (2008) Daniel Panne CURRENT OPINION IN STRUCTURAL BIOLOGY
- Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-κB activation
- (2008) Hidekatsu Iha et al. EMBO JOURNAL
- The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response
- (2008) Constantin S Friedman et al. EMBO REPORTS
- TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway
- (2008) Marie-Cécile Michallet et al. IMMUNITY
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- RNA recognition and signal transduction by RIG-I-like receptors
- (2008) Mitsutoshi Yoneyama et al. IMMUNOLOGICAL REVIEWS
- Suppression of the Deubiquitinating Enzyme USP5 Causes the Accumulation of Unanchored Polyubiquitin and the Activation of p53
- (2008) Saurabh Dayal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TRAF6 and MEKK1 Play a Pivotal Role in the RIG-I-like Helicase Antiviral Pathway
- (2008) Ryoko Yoshida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of IκB Kinase-related Kinases and Antiviral Responses by Tumor Suppressor CYLD
- (2008) Minying Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of Isopeptidase T
- (2008) Francisca E. Reyes-Turcu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Riplet/RNF135, a RING Finger Protein, Ubiquitinates RIG-I to Promote Interferon-β Induction during the Early Phase of Viral Infection
- (2008) Hiroyuki Oshiumi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20
- (2008) Emre E. Turer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5
- (2008) Hiroki Kato et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I
- (2008) Sheng Cui et al. MOLECULAR CELL
- cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination
- (2008) Mathieu J.M. Bertrand et al. MOLECULAR CELL
- Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses
- (2008) Kiyohiro Takahasi et al. MOLECULAR CELL
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
- (2008) Robert R Graham et al. NATURE GENETICS
- Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
- (2008) Stacy L Musone et al. NATURE GENETICS
- Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling
- (2008) Sivakumar Vallabhapurapu et al. NATURE IMMUNOLOGY
- Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
- (2008) Brian J Zarnegar et al. NATURE IMMUNOLOGY
- The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
- (2008) Noula Shembade et al. NATURE IMMUNOLOGY
- Ubiquitin binding mediates the NF-κB inhibitory potential of ABIN proteins
- (2008) S Wagner et al. ONCOGENE
- The ER-Bound RING Finger Protein 5 (RNF5/RMA1) Causes Degenerative Myopathy in Transgenic Mice and Is Deregulated in Inclusion Body Myositis
- (2008) Agnès Delaunay et al. PLoS One
- Both cIAP1 and cIAP2 regulate TNF -mediated NF- B activation
- (2008) D. J. Mahoney et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction
- (2008) M. U. Gack et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?
- (2008) Tieu-Lan Chau et al. TRENDS IN BIOCHEMICAL SCIENCES
- UbcH8 regulates ubiquitin and ISG15 conjugation to RIG-I
- (2007) Kei-Ichiro Arimoto et al. MOLECULAR IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started