A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies
出版年份 2014 全文链接
标题
A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies
作者
关键词
Alternative models, Bile canaliculi, CYP450 enzymes, Drug-induced liver injury, Drug metabolism
出版物
ARCHIVES OF TOXICOLOGY
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2014-03-05
DOI
10.1007/s00204-014-1215-9
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
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