Review
Food Science & Technology
Asem Mahmoud Abdelshafy, Tarun Belwal, Ze Liang, Lei Wang, Dong Li, Zisheng Luo, Li Li
Summary: This review comprehensively discusses the recent advances in mushroom phenolic compounds, including their sources, structural characteristics, biological activities, potential uses, and industrial applications. Phenolic acids and flavonoids are considered the most common phenolics in mushrooms, responsible for various bioactivities. The review also highlights edible mushroom species with high phenolic content and biological activity for future applications, along with new areas of mushroom research such as nanoformulation.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Biochemistry & Molecular Biology
Paulina Lysakowska, Aldona Sobota, Anna Wirkijowska
Summary: Medicinal mushrooms are considered new-generation foods with high content of biologically active compounds. They have beneficial effects on overall health and nutritional level, exhibiting anticancer, antioxidant, antidiabetic, and immunomodulatory effects. However, further long-term clinical studies are needed to understand their mechanisms of action. Medicinal mushrooms have great potential in the design of innovative functional foods, though their interactions with food matrix require further research.
Review
Chemistry, Applied
Fei Luan, Xi Peng, Ge Zhao, Jiuseng Zeng, Junbo Zou, Zhili Rao, Yao Liu, Xiumeng Zhang, Hang Ma, Nan Zeng
Summary: Phellinus spp., an important medicinal fungus mushroom cultivated and consumed in East Asia for over 2000 years, has polysaccharides as major bioactive macromolecules with multiple health-promoting effects. While extraction and purification methods, structural characteristics, and pharmacological activities of these polysaccharides have been extensively studied, there is limited knowledge on their structures and bioactivity relationship, toxicologic effects, and pharmacokinetic profile. This review systematically summarizes recent progress in the isolation and purification, chemical structures, bioactivities, and underlying mechanisms of PPs, providing insights for their further development as therapeutic agents and functional foods.
Review
Biochemistry & Molecular Biology
Katarzyna Sulkowska-Ziaja, Monika Balik, Bozena Muszynska
Summary: This study presents the current knowledge on the chemical composition, biological activity, and possible medicinal applications of the inedible arboreal species Phellinus igniarius, Phellinus pini, Phellinus pomaceus, and Phellinus robustus. These species, known for centuries in traditional medicine of the Far East, have been used as remedies for stomach and intestinal ailments, diarrhea, and hemorrhages. Polysaccharides, phenolic compounds, and terpenoids have been identified in these species, showing biological activities such as anticancer, antioxidant, antiangiogenic, and antiviral properties. Research studies have advanced the knowledge on the therapeutic potential of compounds isolated both from fruiting bodies and biomass obtained through in vitro biotechnological methods.
CHEMISTRY & BIODIVERSITY
(2021)
Review
Biochemistry & Molecular Biology
Sechul Chun, Judy Gopal, Manikandan Muthu
Summary: This article discusses the medicinal properties and bioactivity of mushrooms, focusing on the antioxidant and antiviral properties of mushroom polysaccharides. It also points out the relatively limited research on mushroom polysaccharides compared to overall mushroom studies.
Article
Nutrition & Dietetics
Abdul Mueed, Sahar Shibli, Diana A. Al-Quwaie, Mada F. Ashkan, Mona Alharbi, Humidah Alanazi, Najat Binothman, Majidah Aljadani, Kamlah Ali Majrashi, Mashael Huwaikem, Mohammed A. S. Abourehab, Sameh A. Korma, Mohamed T. El-Saadony
Summary: This study extracted and determined the polyphenols from indigenous plants and evaluated their antioxidant, cytotoxicity, antimicrobial, and enzyme inhibition properties. The results demonstrated significant antioxidant activity and high polyphenol content in the medicinal plant extracts. Some extracts also showed significant cytotoxicity and antibacterial activity. These findings highlight the therapeutic effectiveness of indigenous plants and their importance as natural reserves of phytochemical compounds.
FRONTIERS IN NUTRITION
(2023)
Article
Medicine, Research & Experimental
Ruth W. Mwangi, John M. Macharia, Isabel N. Wagara, Raposa L. Bence
Summary: Mushrooms have gained popularity due to their high nutritional value, delicious taste, and enticing aroma. They are consumed as food and are also considered important for treating various ailments and as a valuable commodity for commerce worldwide. Higher Ascomycetes and Basidiomycetes mushrooms have potential anticancer and immunological properties, as well as a wide range of pharmacological effects.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Biochemistry & Molecular Biology
Chang Tan, Mingyue Wang, Yanwen Kong, Meizhi Wan, Haotian Deng, Yuqi Tong, Chunmao Lyu, Xianjun Meng
Summary: This study investigated the anti-inflammatory effects of cyanidin-3-glucoside and blueberry pectin complexes on mice with colitis. The results showed that the complexes, after high hydrostatic pressure treatment, significantly alleviated diarrhea and colon shortening, and improved gut microbiota composition. The potential mechanism of action involved reduction in intestinal oxidative stress and inflammatory factors expression, improvement in anti-inflammatory factor levels, and inhibition of the NF-kappa B signaling pathway.
Review
Green & Sustainable Science & Technology
Shifa Shaffique, Sang-Mo Kang, Ah-Yeong Kim, Muhammad Imran, Muhammad Aaqil Khan, In-Jung Lee
Summary: The renewed interest in medicinal mushrooms highlights their sustainable health benefits. Mushrooms contain a variety of bioactive metabolites, with Ganoderma tsugae Murill showing excellent antioxidant potential.
Article
Biochemistry & Molecular Biology
Eryka Oliveira de Andrades, Joao Marcos Antonio Rodrigues da Costa, Francisco Edmar Moreira de Lima Neto, Alyne Rodrigues de Araujo, Fabio de Oliveira Silva Ribeiro, Andreanne Gomes Vasconcelos, Antonia Carla de Jesus Oliveira, Jose Lamartine Soares Sobrinho, Miguel Peixoto de Almeida, Ana P. Carvalho, Jhones Nascimento Dias, Ingrid Gracielle Martins Silva, Patricia Albuquerque, Ildinete Silva Pereira, Doralina do Amaral Rabello, Adriany das Gracas Nascimento Amorim, Jose Roberto de Souza de Almeida Leite, Durcilene Alves da Silva
Summary: This study developed fucan-coated nanoparticles for the stabilization of lycopene, showing good stability and antioxidant activity, significant cytotoxicity against breast cancer cells, no impact on keratinocytes, and non-toxic effects in both in vitro and in vivo models.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Fisheries
Kannan Mohan, Durairaj Karthick Rajan, Thirunavukkarasu Muralisankar, Abirami Ramu Ganesan, Kasi Marimuthu, Palanivel Sathishkumar
Summary: The aquaculture industry plays a vital role in providing food security for mankind, but it faces challenges in treating infectious diseases. The use of antibiotics and other agents has led to resistance and pollution. Natural compounds derived from mushrooms have gained attention for their non-toxic and eco-friendly properties. Using mushrooms in aquaculture can improve the health and immunity of aquatic animals.
REVIEWS IN AQUACULTURE
(2022)
Article
Biochemistry & Molecular Biology
Jasmina Dimitrova-Shumkovska, Frosina Kosharkoska-Spasovska, Ljupcho Krstanoski, Mitko Karadelev
Summary: The aim of this study was to investigate the antioxidant profile of yogurt fortified with extracts from Phellinus torulosus and Phellinus igniarius. The results showed that yogurt fortified with P. torulosus had higher inhibition rates and stronger antioxidant activity compared to yogurt fortified with P. igniarius. Prolonged refrigeration tended to equalize the antioxidant profiles in both fortified yogurts.
JOURNAL OF FOOD BIOCHEMISTRY
(2022)
Article
Green & Sustainable Science & Technology
Rossana V. C. Cardoso, Marcio Carocho, Angela Fernandes, Jose Pinela, Dejan Stojkovic, Marina Sokovic, Diego Cunha Zied, Juan Diego Valenzuela Cobos, Ana M. Gonzalez-Paramas, Isabel C. F. R. Ferreira, Lillian Barros
Summary: The study found that moderate supplementation (up to 1%) of minerals to oyster mushrooms seemed to have a positive impact on the quality of mushrooms from Mogi-das-Cruzes region, while high supplementation was more favorable for mushrooms from the Presidente Prudente region. Supplementation showed positive effects in increasing the production of some secondary metabolites in the mushrooms without causing any negative cytotoxic effects.
Article
Biochemistry & Molecular Biology
Tuan Manh Nguyen, Jaisoo Kim, Nguyen The Hung, Nguyen Huu Tho, Do Bich Due, Do Thi Hien
Summary: This study evaluated the extraction yield, antioxidant content, antioxidant capacity, and antibacterial activity of extracts obtained from submerged mycelium (ME) and fruiting body (FBE) of Phellinus robiniae NTH-PR1. The results showed that both ME and FBE contained TPSC, TPC, and TFC, with higher levels found in FBE. The extracts exhibited antioxidant and antibacterial activities against Gram-positive and Gram-negative bacteria. The findings suggest that Ph. robiniae NTH-PR1 can be considered a valuable natural source for the development of functional food, pharmaceutical, and cosmetic products.
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS
(2023)
Article
Engineering, Chemical
Ming-Yu Lung, Kai-Wen Deng
Summary: Phellinu igniarius is a medicinal fungus with anticancer and antioxidant properties. This study investigated the production of polysaccharide in submerged culture of P. igniarius using surfactant, and found that Tween 80 exhibited the greatest exopolysaccharide production.
Article
Biochemistry & Molecular Biology
Jing Si, Ge Meng, Yi Wu, Hong-Fei Ma, Bao-Kai Cui, Yu-Cheng Dai
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Mycology
Xing Ji, Dong-Mei Wu, Chang-Ge Song, Shun Liu, Jing Si, Bao-Kai Cui
MYCOLOGICAL PROGRESS
(2019)
Article
Microbiology
Lin Zhu, Jie Song, Jun-Liang Zhou, Jing Si, Bao-Kai Cui
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Mycology
L. L. Shen, M. Wang, J. L. Zhou, J. H. Xing, B. K. Cui, Y. C. Dai
Article
Mycology
Xing Ji, Dong-Mei Wu, Shun Liu, Jing Si, Bao-Kai Cui
Article
Mycology
Jia-Hui Xing, Jun-Liang Zhou, Bao-Kai Cui
MYCOLOGICAL PROGRESS
(2020)
Article
Mycology
Y. -F. Sun, D. H. Costa-Rezende, J. -H. Xing, J. -L. Zhou, B. Zhang, T. B. Gibertoni, G. Gates, M. Glen, Y. -C. Dai, B. -K. Cui
Article
Microbiology
Shun Liu, Lu-Lu Shen, Yan Wang, Tai-Min Xu, Genevieve Gates, Bao-Kai Cui
Summary: Cyanosporus is a cosmopolitan brown-rot fungal genus characterized by blue-tinted basidiocarps. Recent studies have identified five new species within this genus and transferred fifteen species from another complex. Phylogenetic analyses were conducted using various genetic markers to support these taxonomic changes.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Chang-Ge Song, Yuan-Yuan Chen, Shun Liu, Tai-Min Xu, Xiao-Lan He, Di Wang, Bao-Kai Cui
Summary: In this study, phylogenetic and taxonomic analyses of Phellodon from China were conducted using both single and multi-gene analysis. Three new species were discovered. This study provides a foundation for future phylogenetic studies of the genus.
Article
Mycology
Shun Liu, Yuan-Yuan Chen, Yi-Fei Sun, Xiao-Lan He, Chang-Ge Song, Jing Si, Dong-Mei Liu, Genevieve Gates, Bao-Kai Cui
Summary: Brown-rot fungi are important for forest ecosystems as they degrade wood cellulose and hemicellulose, and contribute to nutrient cycling. Recent studies have shown that the ability to produce brown rot has evolved independently multiple times. This study focuses on the classification and phylogenetic relationships of brown-rot fungi within the Polyporales, based on DNA sequences from various loci. The study proposes new families, genera, species, and combinations, and provides illustrations and descriptions for the new species.
Article
Microbiology
Chang-Ge Song, Yi-Fei Sun, Shun Liu, Yuan-Yuan Chen, Bao-Kai Cui
Summary: In this study, four new species of the Phellodon genus, namely P. caesius, P. henanensis, P. concentricus, and P. subgriseofuscus, were described from China based on morphological characters and molecular evidence. Phylogenetic analyses were conducted using the ITS + nLSU gene regions and the combined sequence dataset of ITS + nLSU + nSSU + RPB1 + RPB2 gene regions. Illustrated descriptions and ecological habits of the newly described species are provided.
Article
Microbiology
Xing Ji, Yi-Fei Sun, Dong-Mei Wu, Neng Gao, Bao-Kai Cui
Summary: In this study, phylogenetic analyses were conducted on Perenniporia species and related genera using DNA sequences of multiple loci. It was found that the genus Perenniporia is polyphyletic. Based on morphology and phylogeny, 15 new genera were proposed, 2 new species were described, and 37 new combinations were proposed. Illustrated descriptions of the new species were provided, along with identification keys to Perenniporia and its related genera.
Article
Microbiology
Hao Wang, Jin-Xin Ma, Dong-Mei Wu, Neng Gao, Jing Si, Bao-Kai Cui
Summary: This study investigated the bioactive components and antioxidant activities of various species of Sanghuangporus fungi. The results showed that the antioxidant capacity of Sanghuangporus is closely related to the contents of flavonoid and ascorbic acid, followed by polyphenol and triterpenoid, and finally, polysaccharide. These findings provide important resources and guidance for the separation, purification, and development of bioactive agents from wild Sanghuangporus species, as well as the optimization of their artificial cultivation conditions.
Article
Mycology
Sergei Polme, Kessy Abarenkov, R. Henrik Nilsson, Bjorn D. Lindahl, Karina Engelbrecht Clemmensen, Havard Kauserud, Nhu Nguyen, Rasmus Kjoller, Scott T. Bates, Petr Baldrian, Tobias Guldberg Froslev, Kristjan Adojaan, Alfredo Vizzini, Ave Suija, Donald Pfister, Hans-Otto Baral, Helle Jarv, Hugo Madrid, Jenni Norden, Jian-Kui Liu, Julia Pawlowska, Kadri Poldmaa, Kadri Partel, Kadri Runnel, Karen Hansen, Karl-Henrik Larsson, Kevin David Hyde, Marcelo Sandoval-Denis, Matthew E. Smith, Merje Toome-Heller, Nalin N. Wijayawardene, Nelson Menolli, Nicole K. Reynolds, Rein Drenkhan, Sajeewa S. N. Maharachchikumbura, Tatiana B. Gibertoni, Thomas Laessoe, William Davis, Yuri Tokarev, Adriana Corrales, Adriene Mayra Soares, Ahto Agan, Alexandre Reis Machado, Andres Arguelles-Moyao, Andrew Detheridge, Angelina de Meiras-Ottoni, Annemieke Verbeken, Arun Kumar Dutta, Bao-Kai Cui, C. K. Pradeep, Cesar Marin, Daniel Stanton, Daniyal Gohar, Dhanushka N. Wanasinghe, Eveli Otsing, Farzad Aslani, Gareth W. Griffith, Thorsten H. Lumbsch, Hans-Peter Grossart, Hossein Masigol, Ina Timling, Inga Hiiesalu, Jane Oja, John Y. Kupagme, Jozsef Geml, Julieta Alvarez-Manjarrez, Kai Ilves, Kaire Loit, Kalev Adamson, Kazuhide Nara, Kati Kungas, Keilor Rojas-Jimenez, Kriss Bitenieks, Laszlo Irinyi, Laszlo Laszlo Nagy, Liina Soonvald, Li-Wei Zhou, Lysett Wagner, M. Catherine Aime, Maarja opik, Maria Isabel Mujica, Martin Metsoja, Martin Ryberg, Martti Vasar, Masao Murata, Matthew P. Nelsen, Michelle Cleary, Milan C. Samarakoon, Mingkwan Doilom, Mohammad Bahram, Niloufar Hagh-Doust, Olesya Dulya, Peter Johnston, Petr Kohout, Qian Chen, Qing Tian, Rajasree Nandi, Rasekh Amiri, Rekhani Hansika Perera, Renata dos Santos Chikowski, Renato L. Mendes-Alvarenga, Roberto Garibay-Orijel, Robin Gielen, Rungtiwa Phookamsak, Ruvishika S. Jayawardena, Saleh Rahimlou, Samantha C. Karunarathna, Saowaluck Tibpromma, Shawn P. Brown, Siim-Kaarel Sepp, Sunil Mundra, Zhu-Hua Luo, Tanay Bose, Tanel Vahter, Tarquin Netherway, Teng Yang, Tom May, Torda Varga, Wei Li, Victor Rafael Matos Coimbra, Virton Rodrigo Targino de Oliveira, Vitor Xavier de Lima, Vladimir S. Mikryukov, Yongzhong Lu, Yosuke Matsuda, Yumiko Miyamoto, Urmas Koljalg, Leho Tedersoo
Summary: The article introduces a database FungalTraits to facilitate functional assignments and ecological interpretation of fungi, discussing the challenges between molecular identification of fungal diversity and knowledge of functional traits. Through the involvement of expert knowledge and tools, researchers reannotated a large number of fungal and Stramenopila genera, summarizing them into 17 lifestyle-related traits suitable for environmental studies.
Article
Mycology
Hai-Sheng Yuan, Xu Lu, Yu-Cheng Dai, Kevin D. Hyde, Yu-He Kan, Ivana Kusan, Shuang-Hui He, Ning-Guo Liu, V. Venkateswara Sarma, Chang-Lin Zhao, Bao-Kai Cui, Nousheen Yousaf, Guangyu Sun, Shu-Yan Liu, Fang Wu, Chuan-Gen Lin, Monika C. Dayarathne, Tatiana Baptista Gibertoni, Lucas B. Conceicao, Roberto Garibay-Orijel, Margarita Villegas-Rios, Rodolfo Salas-Lizana, Tie-Zheng Wei, Jun-Zhi Qiu, Ze-Fen Yu, Rungtiwa Phookamsak, Ming Zeng, Soumitra Paloi, Dan-Feng Bao, Pranami D. Abeywickrama, De-Ping Wei, Jing Yang, Ishara S. Manawasinghe, Dulanjalee Harishchandra, Rashika S. Brahmanage, Nimali I. de Silva, Danushka S. Tennakoon, Anuruddha Karunarathna, Yusufjon Gafforov, Dhandevi Pem, Sheng-Nan Zhang, Andre L. C. M. de Azevedo Santiago, Jadson Diogo Pereira Bezerra, Balint Dima, Krishnendu Acharya, Julieta Alvarez-Manjarrez, Ali H. Bahkali, Vinod K. Bhatt, Tor Erik Brandrud, Timur S. Bulgakov, E. Camporesi, Ting Cao, Yu-Xi Chen, Yuan-Yuan Chen, Bandarupalli Devadatha, Abdallah M. Elgorban, Long-Fei Fan, Xing Du, Liu Gao, Camila Melo Goncalves, Luis F. P. Gusmao, Naruemon Huanraluek, Margita Jadan, Ruvishika S. Jayawardena, Abdul Nasir Khalid, Ewald Langer, Diogo X. Lima, Nelson Correia de Lima-Junior, Carla Rejane Sousa de Lira, Jian-Kui (Jack) Liu, Shun Liu, Saisamorn Lumyong, Zong-Long Luo, Neven Matocec, M. Niranjan, Jose Ribamar Costa Oliveira-Filho, Viktor Papp, Eduardo Perez-Pazos, Alan J. L. Phillips, Peng-Lei Qiu, Yihua Ren, Rafael F. Castaneda Ruiz, Kamal C. Semwal, Karl Soop, Carlos A. F. de Souza, Cristina Maria Souza-Motta, Li-Hua Sun, Meng-Le Xie, Yi-Jian Yao, Qi Zhao, Li-Wei Zhou