Regulation of Protein Tyrosine Phosphatase Oxidation in Cell Adhesion and Migration

Thioredoxin-Interacting Protein Expression Is Required for VEGF-Mediated Angiogenic Signal in Endothelial Cells

(2013) Mohammed A. Abdelsaid et al.   ANTIOXIDANTS & REDOX SIGNALING

Polysulfides Link H2S to Protein Thiol Oxidation

(2013) Romy Greiner et al.   ANTIOXIDANTS & REDOX SIGNALING

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thioredoxin-related Protein 32 (TRP32) Specifically Reduces Oxidized Phosphatase of Regenerating Liver (PRL)

(2013) Tasuku Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ROS-mediated activation of AKT induces apoptosis via pVHL in prostate cancer cells

(2013) Mahandranauth A. Chetram et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Structure of the catalytic domain of protein tyrosine phosphatase sigma in the sulfenic acid form

(2013) Tae Jin Jeon et al.   MOLECULES AND CELLS

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

(2013) Amira Othman et al.   PLoS One

Association of the Protein-Tyrosine Phosphatase DEP-1 with Its Substrate FLT3 Visualized by In Situ Proximity Ligation Assay

(2013) Sylvia-Annette Böhmer et al.   PLoS One

S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic stroke

(2013) Z.-Q. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-  receptor tyrosine kinase signaling

(2013) M. Dagnell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

(2013) Makoto Hayashi et al.   Nature Communications

Tyrosine phosphatase PTP-MEG2 negatively regulates vascular endothelial growth factor receptor signaling and function in endothelial cells

(2012) Qin Hao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Redox regulation of protein tyrosine phosphatase activity by hydroxyl radical

(2012) Fan-Guo Meng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ

(2012) R. Godfrey et al.   BLOOD

Fluorescent probes for sensing and imaging biological hydrogen sulfide

(2012) Vivian S Lin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Methods to monitor classical protein-tyrosine phosphatase oxidation

(2012) Robert Karisch et al.   FEBS Journal

Protein tyrosine phosphatase structure-function relationships in regulation and pathogenesis

(2012) Frank Böhmer et al.   FEBS Journal

Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction

(2012) Nicholas K. Tonks   FEBS Journal

Pyrroloquinoline quinone stimulates epithelial cell proliferation by activating epidermal growth factor receptor through redox cycling

(2012) Kazuki Kimura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protection of CDC25 phosphatases against oxidative stress in breast cancer cells: Evaluation of the implication of the thioredoxin system

(2012) Adeline Beillerot et al.   FREE RADICAL RESEARCH

S-glutathionylation of LMW-PTP regulates VEGF-mediated FAK activation and endothelial cell migration

(2012) M. A. Abdelsaid et al.   JOURNAL OF CELL SCIENCE

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

(2012) Giovanna Leoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Reactive Oxygen Species and Epidermal Growth Factor Are Antagonistic Cues Controlling SHP-2 Dimerization

(2012) A. P. Nardozza et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of Hydrogen Peroxide to Peroxytetradecanoic Acid Is Responsible for Potent Inhibition of Protein Tyrosine Phosphatase CD45

(2012) Alicja Kuban-Jankowska et al.   PLoS One

Redox regulation of MAPK phosphatase 1 controls monocyte migration and macrophage recruitment

(2012) H. S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems

(2011) Alexander R. Lippert et al.   ACCOUNTS OF CHEMICAL RESEARCH

ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells

(2011) Mahandranauth A. Chetram et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Conformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase Activity

(2011) Aftabul Haque et al.   CELL

Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

(2011) Robert Karisch et al.   CELL

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases

(2011) Åsa Sandin et al.   CELLULAR SIGNALLING

The impact of the coronary collateral circulation on mortality: a meta-analysis

(2011) Pascal Meier et al.   EUROPEAN HEART JOURNAL

Regulation of protein tyrosine phosphatases by reversible oxidation

(2011) Arne Östman et al.   JOURNAL OF BIOCHEMISTRY

Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 Signaling

(2011) Deepika Arora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides

(2011) Sue Goo Rhee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Biological Buffer Bicarbonate/CO2Potentiates H2O2-Mediated Inactivation of Protein Tyrosine Phosphatases

(2011) Haiying Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen species

(2011) Kyung-Jin Cho et al.   MOLECULES AND CELLS

Identification of protein nitrosothiols using phosphine-mediated selective reduction

(2011) Sheng Li et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen Peroxide Probes Directed to Different Cellular Compartments

(2011) Mikalai Malinouski et al.   PLoS One

Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases

(2011) P. A. Swanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

(2011) N. Krishnan et al.   Science Signaling

Toxicological Disruption of Signaling Homeostasis: Tyrosine Phosphatases as Targets

(2010) James M. Samet et al.   Annual Review of Pharmacology and Toxicology

Irreversible Inactivation of Glutathione Peroxidase 1 and Reversible Inactivation of Peroxiredoxin II by H2O2 in Red Blood Cells

(2010) Chun-Seok Cho et al.   ANTIOXIDANTS & REDOX SIGNALING

Does Cellular Hydrogen Peroxide Diffuse or Act Locally?

(2010) Natalia M. Mishina et al.   ANTIOXIDANTS & REDOX SIGNALING

The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

(2010) Amanda E. Lane et al.   BIOCHEMICAL JOURNAL

A genetically encoded sensor for H2O2 with expanded dynamic range

(2010) Kseniya N. Markvicheva et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling

(2010) Hyun Ae Woo et al.   CELL

Oxidative Inactivation of the Lipid Phosphatase Phosphatase and Tensin Homolog on Chromosome Ten (PTEN) as a Novel Mechanism of Acquired Long QT Syndrome

(2010) Xiaoping Wan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular SOD-Derived H2O2 Promotes VEGF Signaling in Caveolae/Lipid Rafts and Post-Ischemic Angiogenesis in Mice

(2010) Jin Oshikawa et al.   PLoS One

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

(2010) M. Conrad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive oxygen species and insulin resistance: the good, the bad and the ugly

(2010) Tony Tiganis   TRENDS IN PHARMACOLOGICAL SCIENCES

Crystal Structure of the Human Lymphoid Tyrosine Phosphatase Catalytic Domain: Insights into Redox Regulation,

(2009) Sophia J. Tsai et al.   BIOCHEMISTRY

Redox Regulation of SH2-Domain-Containing Protein Tyrosine Phosphatases by Two Backdoor Cysteines

(2009) Cheng-Yu Chen et al.   BIOCHEMISTRY

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Diabetes Mellitus Activates Signal Transduction Pathways Resulting in Vascular Endothelial Growth Factor Resistance of Human Monocytes

(2009) Vadim Tchaikovski et al.   CIRCULATION

Drug Discovery and Protein Tyrosine Phosphatases

(2009) Mark Blaskovich   CURRENT MEDICINAL CHEMISTRY

Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity

(2009) Juxiang Cao et al.   EMBO JOURNAL

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

(2009) Sofie Mellberg et al.   FASEB JOURNAL

Redox Regulation of the Human Dual Specificity Phosphatase YVH1 through Disulfide Bond Formation

(2009) Christopher A. Bonham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Dimerization of tyrosine phosphatase PTPRO decreases its activity and ability to inactivate TrkC

(2009) Amy E. Hower et al.   JOURNAL OF NEUROCHEMISTRY

Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway

(2009) R Naughton et al.   LEUKEMIA

Urotensin II Induces Rat Cardiomyocyte Hypertrophy via the Transient Oxidization of Src Homology 2-Containing Tyrosine Phosphatase and Transactivation of Epidermal Growth Factor Receptor

(2009) J.-C. Liu et al.   MOLECULAR PHARMACOLOGY

NADPH Oxidase-Dependent Signaling in Endothelial Cells: Role in Physiology and Pathophysiology

(2008) Randall S. Frey et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutaredoxin systems

(2008) Christopher Horst Lillig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Oxidative inactivation of protein tyrosine phosphatase 1B by organic hydroperoxides

(2008) Sanjib Bhattacharya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Role of Protein Tyrosine Phosphatase 1B in Vascular Endothelial Growth Factor Signaling and Cell–Cell Adhesions in Endothelial Cells

(2008) Yoshimasa Nakamura et al.   CIRCULATION RESEARCH

Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR

(2008) Fatiha Tabet et al.   CIRCULATION RESEARCH

Protein tyrosine phosphatases: functional inferences from mouse models and human diseases

(2008) Wiljan J. A. J. Hendriks et al.   FEBS Journal

Protein tyrosine phosphatases: regulatory mechanisms

(2008) Jeroen den Hertog et al.   FEBS Journal

Thiol chemistry and specificity in redox signaling

(2008) Christine C. Winterbourn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox Regulation of Interleukin-4 Signaling

(2008) Pankaj Sharma et al.   IMMUNITY

p66Shc-generated Oxidative Signal Promotes Fat Accumulation

(2008) Ina Berniakovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CysteineS-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation

(2008) Yi-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY

The protein tyrosine phosphatase TCPTP controls VEGFR2 signalling

(2008) E. Mattila et al.   JOURNAL OF CELL SCIENCE

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

(2008) Ana Silva et al.   JOURNAL OF CLINICAL INVESTIGATION

New Role for the Protein Tyrosine Phosphatase DEP-1 in Akt Activation and Endothelial Cell Survival

(2008) C. Chabot et al.   MOLECULAR AND CELLULAR BIOLOGY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology