Article
Engineering, Environmental
Yang Yang, Qi Zhang, Baiyang Chen, Liangchen Long, Guan Zhang
Summary: This study found that increasing dissolved oxygen in water enhances the production of oxidizing species, while increasing pH decreases the oxidative capacity of the UV/VUV/I- process. The treatability of the UV/VUV/I- process depends on the pH value, with better performance observed at pH 11.0 and below.
FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING
(2022)
Article
Engineering, Environmental
Jong-Gook Kim, Hye-Bin Kim, Won-Gune Jeong, Kitae Baek
Summary: A novel oxidation system combining calcium peroxide and pyrite was proposed for the degradation of oxidizable contaminants in groundwater. This system showed higher efficiency in degrading sulfanilamide compared to conventional Fenton reaction, indicating its effectiveness in groundwater remediation.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Engineering, Environmental
Jaemin Choi, Hak-Hyeon Kim, Ki-Myeong Lee, Na Chen, Min Sik Kim, Jiwon Seo, Donghyun Lee, Haein Cho, Hyoung-il Kim, Jaesang Lee, Hongshin Lee, Changha Lee
Summary: The generation of hydroxyl radicals by visible light-illuminated tungsten oxide is significantly improved in the presence of hydrogen peroxide and bicarbonate ion. The ternary system shows synergistic enhancement in benzoic acid oxidation, with less consumption of hydrogen peroxide compared to the binary system.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Environmental
Yang Li, Christopher J. Miller, Lei Wu, T. David Waite
Summary: This study demonstrates an electrochemical advanced oxidation process (EAOP) that can simultaneously catalyze the hydrogen evolution reaction (HER) and the oxygen reduction reaction (ORR) to generate atomic hydrogen (H*) and hydrogen peroxide (H2O2) in situ. By using a palladium-coated carbon-PTFE gas diffusion electrode (Pd/C GDE) as a catalytic cathode, hydroxyl radicals ((OH)-O-center dot) can be formed by the reaction of electrogenerated H* with H2O2. The H*/GDE process is more effective in degrading organic contaminants compared to the conventional H*/H2O2 process.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Jong-Gook Kim, Hye-Bin Kim, Dong-Hun Shin, Daniel S. Alessi, Eilhann Kwon, Kitae Baek
Summary: This study investigated a novel in-situ generation system combining electrochemical oxidation and pyrite oxidation to enhance oxidation efficiency. The results indicated that the combined system significantly increased the oxidation rate of organic pollutants, demonstrating a synergistic effect.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Lei Wang, Yi Chen, Baiyang Chen, Jie Yang
Summary: This study showed that reduced oxygen mainly generates center dot OH, and photolysis products can trigger the formation of H2O2 under 254 nm UV. Additionally, evidence of direct photolysis-induced indirect photolysis phenomenon was presented, along with a comprehensive methodology to identify the presence and sources of radicals.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Engineering, Environmental
Yelim Kim, Hongshin Lee, Hoon Oh, Zeeshan Haider, Jaemin Choi, Yong-Uk Shin, Hyoung-il Kim, Jaesang Lee
Summary: This study reexamined the mechanisms of oxidative organic degradation by the binary mixture of periodate and H2O2 (PI/H2O2). The findings showed that PI/H2O2 predominantly decomposes organics by ·OH at pH < 5, contradicting previous claims. The study also revealed a potential switch in the major oxidant under varying pH conditions.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Lei Wang, Boqiang Li, Dionysios D. Dionysiou, Baiyang Chen, Jie Yang, Juan Li
Summary: The study found that alcohols have an impact on the reliability of ·OH detection, possibly making the traditional ·OH determination method unreliable or misleading. Through careful investigation, an overlooked reaction pathway during H2O2 and ·OH transformations was revealed, showing that varying oxygen concentrations, pHs, alcohol dosages, and types can affect H2O2 formation, which in turn affects the accuracy of ·OH determination.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Review
Toxicology
Sigurd Lenzen, Volodymyr I. Lushchak, Fritz Scholz
Summary: The toxicity of H2O2 is limited, but it can distribute its toxic effect throughout the cell due to its stability and long half-life. The highly toxic HO• radical is generated from H2O2 and its action is locally restricted. H2O2 acts as a spreader of the HO• radical, and they depend on each other to execute their toxic effects.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Gregory E. Conner
Summary: The redox status of cells is crucial for cellular activities; H2O2 metabolism regulates the redox status by modifying protein cysteine oxidation; Calcium-stimulated epithelial Duox H2O2 synthesis is transient and prevents harmful changes in redox tone following continuous stimulation.
Article
Multidisciplinary Sciences
Bolei Chen, Yu Xia, Rongxiang He, Hongqian Sang, Wenchang Zhang, Juan Li, Lufeng Chen, Pu Wang, Shishang Guo, Yongguang Yin, Ligang Hu, Maoyong Song, Yong Liang, Yawei Wang, Guibin Jiang, Richard N. Zare
Summary: Contact electrification between water and a solid surface leads to the spontaneous production of H2O2 from hydroxyl groups on the surface. The density of hydroxyl groups affects the yield of H2O2. Mass spectrometry confirms the involvement of hydroxyl groups in the generation of H2O2. A model based on the recombination of hydroxyl radicals from surface hydroxyl groups is proposed. The generation of H2O2 is found to be universal on soil and atmospheric fine particle surfaces in a humid environment.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Engineering, Environmental
Tomas Prostejovsky, Alena Kulist'akova, Martin Reli, Radim Zebrak, Kamila Koci
Summary: A continuous flow photochemical pilot plant unit was used to remove VOC from waste gas stream. The efficiency of the system was studied by controlling reaction conditions, detecting intermediates, and analyzing reaction products. The conversion of the model substances depends on the initial concentration of the pollutant, the flow rate, and the type of pollutant. The results showed that the highest conversion was achieved at an initial pollutant concentration of 50 ppmv and a flow rate of 100 m3 center dot h-1. The study provides insights into the degradation pathways of VOCs and presents an effective AOPs system for VOC removal.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2022)
Article
Chemistry, Physical
Zhipeng Luo, Mingtao Liu, Diyong Tang, Yao Xu, Honghua Ran, Jing He, Ke Chen, Jie Sun
Summary: In this study, a facile self-sacrificial template route was used to synthesize heteroatom-doped porous biochar, which exhibited enhanced electrocatalytic activity for H2O2 production and Fe2+ regeneration. The biochar cathode achieved high H2O2 selectivity, efficient H2O2 activation rate, and effective degradation of various organic contaminants within a short time. The electro-Fenton system showed good stability and versatile applicability for organic pollutants remediation in different surface water matrices.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2022)
Review
Engineering, Chemical
Mengying Liu, Yun Xu, Yanjun Zhao, Zheng Wang, Dunyun Shi
Summary: Utilizing H2O2 as a reaction substrate to generate hydroxyl radical offers a promising therapeutic strategy for cancer treatment, yet the limited Fenton catalysts and insufficient endogenous H2O2 content in tumor sites hinder the production of hydroxyl radicals. Providing Fenton catalysts and increasing H2O2 levels within cancer cells are effective strategies to improve the generation of hydroxyl radicals and enhance therapeutic efficacy in cancer treatment.
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING
(2022)
Review
Chemistry, Multidisciplinary
Qiwei Tian, Fengfeng Xue, Yurui Wang, Yuying Cheng, Lu An, Shiping Yang, Xiaoyuan Chen, Gang Huang
Summary: Chemodynamic therapy (CDT) is a novel therapeutic modality that aims to destroy cancer cells using Fenton reactions without external energy input. Various strategies have been explored to enhance the efficiency of CDT, including increasing the production, accelerating generation, and enhancing efficacy of hydroxyl radicals.
Article
Biochemistry & Molecular Biology
Trang Van Tran, Hoa Nguyen, Luyen Vu, ChangWoo Lee
Summary: Glutaredoxin 3 (Grx3) is a redox protein that maintains structural integrity and glutathione (GSH) binding capabilities across different temperatures. This study investigates the roles of specific bonds in Grx3's structure and function, and how psychrophilic Grx3 variants adapt to cold environments. The highly conserved Arg51-Asp69 salt bridge and Gln56-His63 hydrogen bond are crucial for stabilizing the structure and catalytic activity of Grx3. Psychrophilic variants of Grx3 have adapted to cold environments by reducing GSH binding and increasing structural flexibility.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Amanda Lais de Souza Coto, Arthur Alexandre Pereira, Sabrina Dorta Oliveira, Milene Nobrega de Oliveira Moritz, Arthur Moraes Franco da Rocha, Paulo Roberto Dores-Silva, Noeli Soares Melo da Silva, Ana Rita de Araujo Nogueira, Lisandra Marques Gava, Thiago Vagas Seraphim, Julio Cesar Borges
Summary: J-domain proteins form a large molecular chaperone family involved in proteostasis processes, with hDjC20 playing a vital role in mitochondria and being heavily influenced by the presence of Zn+2.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Meiling Zhang, Jiaxiang Zhang, Yan Liang, Shicheng Tian, Shuyang Xie, Tong Zhou, Qin Wang
Summary: This study determined the crystal structures of RGLG2 VWA domain in Arabidopsis thaliana, revealing that Ca2+ ions act as regulators and affect the conformational change of RGLG2-VWA domain.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Alexandra Bork, Sander H. J. Smits, Lutz Schmitt
Summary: This study reveals the structure and calcium ion binding properties of CBL1 protein, and proposes a binding model of CBL1 for Ca2+. Additionally, it provides preliminary insights into the formation of the dimer interface of CBL1.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Evgeniia V. Leisi, Andrey V. Moiseenko, Sofia S. Kudryavtseva, Denis V. Pozdyshev, Vladimir I. Muronetz, Lidia P. Kurochkina
Summary: The pathogenesis of prion diseases involves the transformation of prion protein into an insoluble form. This study found that two phage chaperonins can promote the fibrillation of prion protein in an ATP-dependent manner, resulting in the formation of less toxic large clusters. These fibrils differ in morphology and properties from those formed spontaneously in acidic pH with denaturants.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Gaurab Chowdhury, Saroj Biswas, Yuthika Dholey, Puja Panja, Sumit Das, Subrata Adak
Summary: Magnesium is an important divalent cation for regulating enzyme activity. The binding of Mg2+ through the PAS domain inhibits phosphoglycerate kinase (PGK) activity in LmPAS-PGK at neutral pH, but PGK activity is derepressed at acidic pH. Mutation studies revealed that the Asp-4 residue is crucial for Mg2+ binding at neutral pH.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Shima Ghaedizadeh, Majid Zeinali, Bahareh Dabirmanesh, Behnam Rasekh, Khosrow Khajeh, Ali Mohammad Banaei-Moghaddam
Summary: Implementing hyperthermostable carbonic anhydrases into CO2 capture and storage technologies can increase the rate of CO2 absorption from industrial flue gases. This study successfully improved the thermostability of a known hyperthermostable carbonic anhydrase through rational engineering of a single-point mutation.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Khaled A. Elnahriry, Dorothy C. C. Wai, Lauren M. Ashwood, Muhammad Umair Naseem, Tibor G. Szanto, Shaodong Guo, Gyorgy Panyi, Peter J. Prentis, Raymond S. Norton
Summary: Sea anemone venom contains a peptide called Tst2, which shows sequence similarity to peptides that interact with various ion channels. Recombinant Tst2 was successfully produced and its structure and function were studied. The results showed that Tst2 is an inhibitor of the TRPV1 channel.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
(2024)