Phosphatidylinositol 4-Kinase III Beta Is Essential for Replication of Human Rhinovirus and Its Inhibition Causes a Lethal PhenotypeIn Vivo

Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus

(2013) Anne Décor et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses

(2013) J. Tan et al.   JOURNAL OF VIROLOGY

Human Rhinovirus Species and Season of Infection Determine Illness Severity

(2012) Wai-Ming Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Anti-Hepatitis C Virus Activity and Toxicity of Type III Phosphatidylinositol-4-Kinase Beta Inhibitors

(2012) M. J. LaMarche et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication

(2012) Leen Delang et al.   BIOCHEMICAL PHARMACOLOGY

Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

(2012) Hilde M van der Schaar et al.   CELL RESEARCH

The lipid kinase PI4KIIIβ preserves lysosomal identity

(2012) Sunandini Sridhar et al.   EMBO JOURNAL

Phosphatidylinositol 4-Kinase IIIβ Is Required for Severe Acute Respiratory Syndrome Coronavirus Spike-mediated Cell Entry

(2012) Ning Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of Phosphatidylinositol-4-Kinase III  as a Hepatitis C Virus Drug Target

(2012) F. H. Vaillancourt et al.   JOURNAL OF VIROLOGY

Infection and Propagation of Human Rhinovirus C in Human Airway Epithelial Cells

(2012) W. Hao et al.   JOURNAL OF VIROLOGY

The 3A Protein from Multiple Picornaviruses Utilizes the Golgi Adaptor Protein ACBD3 To Recruit PI4KIII 

(2012) A. L. Greninger et al.   JOURNAL OF VIROLOGY

Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms

(2012) Nihal Altan-Bonnet et al.   TRENDS IN BIOCHEMICAL SCIENCES

Biological characteristics and propagation of human rhinovirus-C in differentiated sinus epithelial cells

(2012) Shamaila Ashraf et al.   VIROLOGY

An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus

(2012) Susanne C. Feil et al.   ACS Medicinal Chemistry Letters

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

(2011) Jun Sasaki et al.   EMBO JOURNAL

Human Rhinovirus Species Associated With Hospitalizations for Acute Respiratory Illness in Young US Children

(2011) Marika K. Iwane et al.   JOURNAL OF INFECTIOUS DISEASES

Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication

(2011) K. L. Berger et al.   JOURNAL OF VIROLOGY

Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C

(2011) Yury A Bochkov et al.   NATURE MEDICINE

West Nile Virus Replication Requires Fatty Acid Synthesis but Is Independent on Phosphatidylinositol-4-Phosphate Lipids

(2011) Miguel A. Martín-Acebes et al.   PLoS One

Experimental Rhinovirus Infection as a Human Model of Chronic Obstructive Pulmonary Disease Exacerbation

(2010) Patrick Mallia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Association between human rhinovirus C and severity of acute asthma in children

(2010) J. Bizzintino et al.   EUROPEAN RESPIRATORY JOURNAL

Weekly monitoring of children with asthma for infections and illness during common cold seasons

(2010) Jaime P. Olenec et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Proposals for the classification of human rhinovirus species C into genotypically assigned types

(2010) P. Simmonds et al.   JOURNAL OF GENERAL VIROLOGY

Phosphatidylinositol 4-Kinase III Beta Is a Target of Enviroxime-Like Compounds for Antipoliovirus Activity

(2010) M. Arita et al.   JOURNAL OF VIROLOGY

Characterization of Dysferlin Deficient SJL/J Mice to Assess Preclinical Drug Efficacy: Fasudil Exacerbates Muscle Disease Phenotype

(2010) Sree Rayavarapu et al.   PLoS One

Mutations in the Nonstructural Protein 3A Confer Resistance to the Novel Enterovirus Replication Inhibitor TTP-8307

(2009) A. M. De Palma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical severity and molecular typing of human rhinovirus C strains during a fall outbreak affecting hospitalized patients

(2009) A. Piralla et al.   JOURNAL OF CLINICAL VIROLOGY

Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime

(2009) M. Arita et al.   JOURNAL OF GENERAL VIROLOGY

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

(2009) J. Borawski et al.   JOURNAL OF VIROLOGY

Evidence of Recombination and Genetic Diversity in Human Rhinoviruses in Children with Acute Respiratory Infection

(2009) Ting Huang et al.   PLoS One

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication

(2009) K. L. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication

(2009) Frédéric H. Vaillancourt et al.   VIROLOGY

A novel group of rhinoviruses is associated with asthma hospitalizations

(2008) E. Kathryn Miller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Distinguishing Molecular Features and Clinical Characteristics of a Putative New Rhinovirus Species, Human Rhinovirus C (HRV C)

(2008) Peter McErlean et al.   PLoS One

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

(2008) S. D. Message et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA