3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses

Picornavirus non-structural proteins as targets for new anti-virals with broad activity

(2011) Heléne Norder et al.   ANTIVIRAL RESEARCH

Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design

(2011) G. Lu et al.   JOURNAL OF VIROLOGY

Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93

(2011) L. Costenaro et al.   JOURNAL OF VIROLOGY

Recent Advances in Targeting Viral Proteases for the Discovery of Novel Antivirals

(2010) Holger Steuber et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structure-based antivirals for emerging and neglected RNA viruses: an emerging field for medicinal chemistry in academia

(2010) Rolf Hilgenfeld   Future Medicinal Chemistry

Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

(2009) Cheng-Chung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enterovirus 71 Outbreak in the People's Republic of China in 2008

(2009) F. Yang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A case for developing antiviral drugs against polio

(2008) Marc S. Collett et al.   ANTIVIRAL RESEARCH

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents

(2008) Chih-Jung Kuo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel CADD-based peptidyl vinyl ester derivatives as potential proteasome inhibitors

(2008) Ke Mou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Structural View of the Inactivation of the SARS Coronavirus Main Proteinase by Benzotriazole Esters

(2008) Koen H.G. Verschueren et al.   CHEMISTRY & BIOLOGY