Evaluation of Phosphatidylinositol-4-Kinase III  as a Hepatitis C Virus Drug Target

Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P2 and Membrane Scission

(2012) Helen Sarantis et al.   Cell Host & Microbe

Phosphatidylinositol 4-Kinase IIIβ Is Required for Severe Acute Respiratory Syndrome Coronavirus Spike-mediated Cell Entry

(2012) Ning Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 3A Protein from Multiple Picornaviruses Utilizes the Golgi Adaptor Protein ACBD3 To Recruit PI4KIII 

(2012) A. L. Greninger et al.   JOURNAL OF VIROLOGY

ARF1 and GBF1 Generate a PI4P-Enriched Environment Supportive of Hepatitis C Virus Replication

(2012) Leiliang Zhang et al.   PLoS One

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

(2012) Annalisa Bianco et al.   PLoS Pathogens

Molecular Determinants and Dynamics of Hepatitis C Virus Secretion

(2012) Kelly E. Coller et al.   PLoS Pathogens

A homogeneous and nonisotopic assay for phosphatidylinositol 4-kinases

(2011) Andrew W. Tai et al.   ANALYTICAL BIOCHEMISTRY

Comparative Study of the Genetic Barriers and Pathways towards Resistance of Selective Inhibitors of Hepatitis C Virus Replication

(2011) Leen Delang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroResistance Profile of the Hepatitis C Virus NS3 Protease Inhibitor BI 201335

(2011) Lisette Lagacé et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic and functional studies of phosphatidyl-inositol 4-kinase type IIIα

(2011) Zsofia Szentpetery et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment

(2011) Simon Reiss et al.   Cell Host & Microbe

The Shigella flexneri Type Three Secretion System Effector IpgD Inhibits T Cell Migration by Manipulating Host Phosphoinositide Metabolism

(2011) Christoph Konradt et al.   Cell Host & Microbe

Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling

(2011) Y. Yan et al.   DEVELOPMENT

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

(2011) Jun Sasaki et al.   EMBO JOURNAL

Notch signaling in intestinal homeostasis across species: the cases of Drosophila, Zebrafish and the mouse

(2011) Silvia Fre et al.   EXPERIMENTAL CELL RESEARCH

Notch: Architect, Landscaper, and Guardian of the Intestine

(2011) Marc Vooijs et al.   GASTROENTEROLOGY

Hepatitis C Virus NS5A Protein Interacts with Phosphatidylinositol 4-Kinase Type IIIα and Regulates Viral Propagation

(2011) Yun-Sook Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication

(2011) K. L. Berger et al.   JOURNAL OF VIROLOGY

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

Boceprevir for Untreated Chronic HCV Genotype 1 Infection

(2011) Fred Poordad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection

(2011) Ira M. Jacobson et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Role of the Phosphatidylinositol 4-Kinase PI4KA in Hepatitis C Virus-Induced Host Membrane Rearrangement

(2011) Andrew W. Tai et al.   PLoS One

Notch Lineages and Activity in Intestinal Stem Cells Determined by a New Set of Knock-In Mice

(2011) Silvia Fre et al.   PLoS One

Anchors for Effectors: Subversion of Phosphoinositide Lipids by Legionella

(2011) Hubert Hilbi et al.   Frontiers in Microbiology

Mechanism of Resistance of Hepatitis C Virus Replicons to Structurally Distinct Cyclophilin Inhibitors

(2010) X. Puyang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

(2010) Nick Barker et al.   Cell Stem Cell

Evolving epidemiology of hepatitis C virus

(2010) D. Lavanchy   CLINICAL MICROBIOLOGY AND INFECTION

Ultrastructural and biochemical analyses of hepatitis C virus-associated host cell membranes

(2010) P. Ferraris et al.   JOURNAL OF GENERAL VIROLOGY

Phosphatidylinositol 4-Kinase III Beta Is a Target of Enviroxime-Like Compounds for Antipoliovirus Activity

(2010) M. Arita et al.   JOURNAL OF VIROLOGY

Host Factors Required for Modulation of Phagosome Biogenesis and Proliferation of Francisella tularensis within the Cytosol

(2010) Christine Akimana et al.   PLoS One

Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein

(2010) B. G. Hale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoinositides Direct Equine Infectious Anemia Virus Gag Trafficking and Release

(2010) Fiona Fernandes et al.   TRAFFIC

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

(2009) Andrew W. Tai et al.   Cell Host & Microbe

Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening

(2009) Maud Trotard et al.   FASEB JOURNAL

Crucial role of phosphatidylinositol 4-kinase III  in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling

(2009) H. Ma et al.   JOURNAL OF CELL SCIENCE

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

(2009) J. Borawski et al.   JOURNAL OF VIROLOGY

Loss of phosphatidylinositol 4-kinase 2α activity causes late onset degeneration of spinal cord axons

(2009) J. Paul Simons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication

(2009) K. L. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

(2009) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication

(2009) Frédéric H. Vaillancourt et al.   VIROLOGY

Adaptation of endoplasmic reticulum exit sites to acute and chronic increases in cargo load

(2008) Hesso Farhan et al.   EMBO JOURNAL

Enteropathogenic Escherichia coli Subverts Phosphatidylinositol 4,5-Bisphosphate and Phosphatidylinositol 3,4,5-Trisphosphate upon Epithelial Cell Infection

(2008) Hagit Sason et al.   MOLECULAR BIOLOGY OF THE CELL

Hepatitis C virus infection protein network

(2008) B de Chassey et al.   Molecular Systems Biology

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS

Maintenance of Hormone-sensitive Phosphoinositide Pools in the Plasma Membrane Requires Phosphatidylinositol 4-Kinase IIIα

(2007) Andras Balla et al.   MOLECULAR BIOLOGY OF THE CELL