标题
Recent Advances in Nanoparticle-Mediated siRNA Delivery
作者
关键词
-
出版物
Annual Review of Biomedical Engineering
Volume 16, Issue 1, Pages 347-370
出版商
Annual Reviews
发表日期
2014-06-07
DOI
10.1146/annurev-bioeng-071813-105119
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Molecular Parameters of siRNA–Cell Penetrating Peptide Nanocomplexes for Efficient Cellular Delivery
- (2013) Alexander H. van Asbeck et al. ACS Nano
- Mechanism of Polyplex- and Lipoplex-Mediated Delivery of Nucleic Acids: Real-Time Visualization of Transient Membrane Destabilization without Endosomal Lysis
- (2013) Zia ur Rehman et al. ACS Nano
- Non-Viral Gene Delivery via Membrane-Penetrating, Mannose-Targeting Supramolecular Self-Assembled Nanocomplexes
- (2013) Lichen Yin et al. ADVANCED MATERIALS
- Supramolecular Self-Assembled Nanoparticles Mediate Oral Delivery of Therapeutic TNF-α siRNA against Systemic Inflammation
- (2013) Lichen Yin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Molecular Mechanisms of RNA Interference
- (2013) Ross C. Wilson et al. Annual Review of Biophysics
- Disulfide bond-conjugated dual PEGylated siRNAs for prolonged multiple gene silencing
- (2013) Zi-Xian Liao et al. BIOMATERIALS
- Protein-resistant, reductively dissociable polyplexes for in vivo systemic delivery and tumor-targeting of siRNA
- (2013) Jee Seon Kim et al. BIOMATERIALS
- Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy
- (2013) Yuan Zhang et al. BIOMATERIALS
- Effect of binding affinity for siRNA on the in vivo antitumor efficacy of polyplexes
- (2013) Lu Han et al. BIOMATERIALS
- A bioreducible linear poly(β-amino ester) for siRNA delivery
- (2013) Kristen L. Kozielski et al. CHEMICAL COMMUNICATIONS
- siRNA nanomedicine: the promise of bioreducible materials
- (2013) Kristen L Kozielski et al. Expert Review of Medical Devices
- Alkane-modified low-molecular-weight polyethylenimine with enhanced gene silencing for siRNA delivery
- (2013) Gaoyang Guo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Codelivery of VEGF siRNA and Gemcitabine Monophosphate in a Single Nanoparticle Formulation for Effective Treatment of NSCLC
- (2013) Yuan Zhang et al. MOLECULAR THERAPY
- Lipidoid-Coated Iron Oxide Nanoparticles for Efficient DNA and siRNA delivery
- (2013) Shan Jiang et al. NANO LETTERS
- Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
- (2013) Jerome Gilleron et al. NATURE BIOTECHNOLOGY
- Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
- (2013) Gaurav Sahay et al. NATURE BIOTECHNOLOGY
- Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
- (2013) Stefan Tenzer et al. Nature Nanotechnology
- Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis
- (2013) Teresa Coelho et al. NEW ENGLAND JOURNAL OF MEDICINE
- Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
- (2013) C. A. Alabi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A vector-free microfluidic platform for intracellular delivery
- (2013) A. Sharei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Vivo Delivery of RNAi by Reducible Interfering Nanoparticles (iNOPs)
- (2013) Huricha Baigude et al. ACS Medicinal Chemistry Letters
- First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement
- (2013) Josep Tabernero et al. Cancer Discovery
- FRET-Labeled siRNA Probes for Tracking Assembly and Disassembly of siRNA Nanocomplexes
- (2012) Christopher A. Alabi et al. ACS Nano
- Identification and Characterization of Receptor-Specific Peptides for siRNA Delivery
- (2012) Yin Ren et al. ACS Nano
- Targeting the Blind Spot of Polycationic Nanocarrier-Based siRNA Delivery
- (2012) Mengyao Zheng et al. ACS Nano
- Targeted Polymeric Micelles for siRNA Treatment of Experimental Cancer by Intravenous Injection
- (2012) R. James Christie et al. ACS Nano
- Polymeric Nucleic Acid Vehicles Exploit Active Interorganelle Trafficking Mechanisms
- (2012) Katye M. Fichter et al. ACS Nano
- Reductively Dissociable siRNA-Polymer Hybrid Nanogels for Efficient Targeted Gene Silencing
- (2012) Cheol Am Hong et al. ADVANCED FUNCTIONAL MATERIALS
- Plasmid-Templated Shape Control of Condensed DNA-Block Copolymer Nanoparticles
- (2012) Xuan Jiang et al. ADVANCED MATERIALS
- Tumor-Homing Poly-siRNA/Glycol Chitosan Self-Cross-Linked Nanoparticles for Systemic siRNA Delivery in Cancer Treatment
- (2012) So Jin Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Phenylboronate-Functionalized Polyion Complex Micelle for ATP-Triggered Release of siRNA
- (2012) Mitsuru Naito et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers
- (2012) Mengyao Zheng et al. BIOMATERIALS
- Lipid nanoparticles for hepatic delivery of small interfering RNA
- (2012) Bo Yu et al. BIOMATERIALS
- Cystamine-terminated poly(beta-amino ester)s for siRNA delivery to human mesenchymal stem cells and enhancement of osteogenic differentiation
- (2012) Stephany Y. Tzeng et al. BIOMATERIALS
- Structural modification of siRNA for efficient gene silencing
- (2012) So Jin Lee et al. BIOTECHNOLOGY ADVANCES
- Stabilization of polyplexes via polymer crosslinking for efficient siRNA delivery
- (2012) Thomas Fröhlich et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles
- (2012) Christopher A. Alabi et al. Integrative Biology
- Anti-Her2 single-chain antibody mediated DNMTs-siRNA delivery for targeted breast cancer therapy
- (2012) Shuang Dou et al. JOURNAL OF CONTROLLED RELEASE
- Sequence-defined four-arm oligo(ethanamino)amides for pDNA and siRNA delivery: Impact of building blocks on efficacy
- (2012) Eveline E. Salcher et al. JOURNAL OF CONTROLLED RELEASE
- Structure–activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides
- (2012) Thomas Fröhlich et al. JOURNAL OF CONTROLLED RELEASE
- Oral delivery of small RNA and DNA
- (2012) Diane C. Forbes et al. JOURNAL OF CONTROLLED RELEASE
- N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver
- (2012) Hong-Xia Wang et al. JOURNAL OF CONTROLLED RELEASE
- Encapsidation of RNA–Polyelectrolyte Complexes with Amphiphilic Block Copolymers: Toward a New Self-Assembly Route
- (2012) Laurent Bui et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing
- (2012) Stuart S. Dunn et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Therapeutic Delivery of siRNA Silencing HIF-1 Alpha with Micellar Nanoparticles Inhibits Hypoxic Tumor Growth
- (2012) Xi-Qiu Liu et al. MOLECULAR PHARMACEUTICS
- A Cell-penetrating Helical Polymer For siRNA Delivery to Mammalian Cells
- (2012) Nathan P Gabrielson et al. MOLECULAR THERAPY
- The Possible “Proton Sponge ” Effect of Polyethylenimine (PEI) Does Not Include Change in Lysosomal pH
- (2012) Rikke V Benjaminsen et al. MOLECULAR THERAPY
- Self-assembled RNA interference microsponges for efficient siRNA delivery
- (2012) Jong Bum Lee et al. NATURE MATERIALS
- Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
- (2012) Hyukjin Lee et al. Nature Nanotechnology
- Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect
- (2012) Mayumi Takahashi et al. NUCLEIC ACIDS RESEARCH
- Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation
- (2012) Dan Zheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4
- (2012) Y. Ren et al. Science Translational Medicine
- Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis
- (2012) Y.-d. Yao et al. Science Translational Medicine
- Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer
- (2012) Stephany Y. Tzeng et al. Advanced Healthcare Materials
- Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing
- (2012) Christian Dohmen et al. Molecular Therapy-Nucleic Acids
- The Business of RNAi Therapeutics in 2012
- (2012) Dirk Haussecker Molecular Therapy-Nucleic Acids
- Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery
- (2011) Haijun Yu et al. ACS Nano
- Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression
- (2011) Tian-Meng Sun et al. ACS Nano
- Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery
- (2011) Xian-Zhu Yang et al. ACS Nano
- Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration
- (2011) Vikash P. Chauhan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Solid-Phase Synthesis of Sequence-Defined T-, i-, and U-Shape Polymers for pDNA and siRNA Delivery
- (2011) David Schaffert et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Effect of Polymer Structure on Micelles Formed between siRNA and Cationic Block Copolymer Comprising Thiols and Amidines
- (2011) R. James Christie et al. BIOMACROMOLECULES
- Target specific systemic delivery of TGF-β siRNA/(PEI-SS)-g-HA complex for the treatment of liver cirrhosis
- (2011) Kitae Park et al. BIOMATERIALS
- Dual mode polyspermine with tunable degradability for plasmid DNA and siRNA delivery
- (2011) Min Suk Shim et al. BIOMATERIALS
- Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma
- (2011) Stephany Y. Tzeng et al. BIOMATERIALS
- In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly(ethylene glycol) block copolymers
- (2011) Olivia M. Merkel et al. BIOMATERIALS
- Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid
- (2011) Hiroto Hatakeyama et al. BIOMATERIALS
- Inflammatory responses to pulmonary application of PEI-based siRNA nanocarriers in mice
- (2011) Andrea Beyerle et al. BIOMATERIALS
- Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain
- (2011) Tomoya Suma et al. BIOMATERIALS
- Current progress of siRNA/shRNA therapeutics in clinical trials
- (2011) John C. Burnett et al. Biotechnology Journal
- Protein transduction domain delivery of therapeutic macromolecules
- (2011) Arjen van den Berg et al. CURRENT OPINION IN BIOTECHNOLOGY
- Tumor vasculature is a key determinant for the efficiency of nanoparticle-mediated siRNA delivery
- (2011) L Li et al. GENE THERAPY
- In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy
- (2011) Takahiro Nomoto et al. JOURNAL OF CONTROLLED RELEASE
- Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy
- (2011) Xian-Zhu Yang et al. JOURNAL OF CONTROLLED RELEASE
- Alkane-modified short polyethyleneimine for siRNA delivery
- (2011) Avi Schroeder et al. JOURNAL OF CONTROLLED RELEASE
- PEG-detachable cationic polyaspartamide derivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor
- (2011) Hyun Jin Kim et al. JOURNAL OF DRUG TARGETING
- Gene Silencing by siRNA Microhydrogels via Polymeric Nanoscale Condensation
- (2011) Cheol Am Hong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- FRET-based probing to gain direct information on siRNA sustainability in live cells: Asymmetric degradation of siRNA strands
- (2011) Seonmi Shin et al. Molecular BioSystems
- Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery
- (2011) Kathryn A Whitehead et al. MOLECULAR THERAPY
- Is RNAi Dead?
- (2011) Arthur M Krieg MOLECULAR THERAPY
- Delivery of Multiple siRNAs Using Lipid-Coated PLGA Nanoparticles for Treatment of Prostate Cancer
- (2011) Warefta Hasan et al. NANO LETTERS
- Therapeutic siRNA silencing in inflammatory monocytes in mice
- (2011) Florian Leuschner et al. NATURE BIOTECHNOLOGY
- The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
- (2011) Carlee E. Ashley et al. NATURE MATERIALS
- Enhanced Stability and Knockdown Efficiency of Poly(ethylene glycol)-b-polyphosphoramidate/siRNA Micellar Nanoparticles by Co-condensation with Sodium Triphosphate
- (2011) Masataka Nakanishi et al. PHARMACEUTICAL RESEARCH
- Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
- (2011) Daniel J. Siegwart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine–hyaluronic acid conjugate
- (2010) Kitae Park et al. BIOMATERIALS
- Breaking down the barriers: siRNA delivery and endosome escape
- (2010) M. Dominska et al. JOURNAL OF CELL SCIENCE
- Self-assembled siRNA–PLGA conjugate micelles for gene silencing
- (2010) Soo Hyeon Lee et al. JOURNAL OF CONTROLLED RELEASE
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver
- (2010) Weikang Tao et al. MOLECULAR THERAPY
- Elimination Pathways of Systemically Delivered siRNA
- (2010) Yuanyu Huang et al. MOLECULAR THERAPY
- Polymer- and lipid-based nanoparticle therapeutics for the treatment of liver diseases
- (2010) Lanjuan Li et al. Nano Today
- Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
- (2010) Mark E. Davis et al. NATURE
- Lipid-like materials for low-dose, in vivo gene silencing
- (2010) K. T. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Delivery of RNA interference therapeutics using polycation-based nanoparticles
- (2009) Kenneth Alan Howard ADVANCED DRUG DELIVERY REVIEWS
- siRNA delivery systems for cancer treatment
- (2009) Yu-Kyoung Oh et al. ADVANCED DRUG DELIVERY REVIEWS
- Acid-Responsive Linear Polyethylenimine for Efficient, Specific, and Biocompatible siRNA Delivery
- (2009) Min Suk Shim et al. BIOCONJUGATE CHEMISTRY
- Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging
- (2009) Olivia M. Merkel et al. JOURNAL OF CONTROLLED RELEASE
- Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing
- (2009) Seung-Young Lee et al. JOURNAL OF CONTROLLED RELEASE
- Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver
- (2009) Akin Akinc et al. MOLECULAR THERAPY
- Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment
- (2009) Marc T Abrams et al. MOLECULAR THERAPY
- The promises and pitfalls of RNA-interference-based therapeutics
- (2009) Daniela Castanotto et al. NATURE
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery
- (2008) Jordan J. Green et al. ACCOUNTS OF CHEMICAL RESEARCH
- Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity
- (2008) Arkadi Zintchenko et al. BIOCONJUGATE CHEMISTRY
- Environment-Responsive Block Copolymer Micelles with a Disulfide Cross-Linked Core for Enhanced siRNA Delivery
- (2008) Satoru Matsumoto et al. BIOMACROMOLECULES
- The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer
- (2008) E Wisse et al. GENE THERAPY
- An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
- (2008) Sumio Chono et al. JOURNAL OF CONTROLLED RELEASE
- Lipofectamine RNAiMAX: An Efficient siRNA Transfection Reagent in Human Embryonic Stem Cells
- (2008) Ming Zhao et al. MOLECULAR BIOTECHNOLOGY
- Drug delivery of siRNA therapeutics: potentials and limits of nanosystems
- (2008) Daniela Reischl et al. Nanomedicine-Nanotechnology Biology and Medicine
- Resolution of liver cirrhosis using vitamin A–coupled liposomes to deliver siRNA against a collagen-specific chaperone
- (2008) Yasushi Sato et al. NATURE BIOTECHNOLOGY
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- Chemical Modification Patterns Compatible with High Potency Dicer-Substrate Small Interfering RNAs
- (2008) Michael A. Collingwood et al. OLIGONUCLEOTIDES
- Systemic Delivery of DNA or siRNA Mediated by Linear Polyethylenimine (L-PEI) Does Not Induce an Inflammatory Response
- (2008) Marie-Elise Bonnet et al. PHARMACEUTICAL RESEARCH
- Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
- (2008) M. Frank-Kamenetsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Innate immune response induced by gene delivery vectors
- (2007) Haruna Sakurai et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started