Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization
出版年份 2014 全文链接
标题
Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization
作者
关键词
-
出版物
ANNALS OF NEUROLOGY
Volume 77, Issue 1, Pages 15-32
出版商
Wiley
发表日期
2014-11-01
DOI
10.1002/ana.24294
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A single nucleotide polymorphism in the coding region of PGC-1α is a male-specific modifier of Huntington disease age-at-onset in a large European cohort
- (2014) Patrick Weydt et al. BMC Neurology
- Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease
- (2014) Roberta Tufi et al. NATURE CELL BIOLOGY
- Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease
- (2014) Falk Schlaudraff et al. NEUROBIOLOGY OF AGING
- Proteomic analysis of human substantia nigra identifies novel candidates involved in Parkinson's disease pathogenesis
- (2014) Virginie Licker et al. PROTEOMICS
- Mitochondrial Abnormality Associates with Type-Specific Neuronal Loss and Cell Morphology Changes in the Pedunculopontine Nucleus in Parkinson Disease
- (2013) Ilse S. Pienaar et al. AMERICAN JOURNAL OF PATHOLOGY
- PGC-1α, mitochondrial dysfunction, and Huntington's disease
- (2013) Ashu Johri et al. FREE RADICAL BIOLOGY AND MEDICINE
- PGC-1 is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis
- (2013) J. Eschbach et al. HUMAN MOLECULAR GENETICS
- TFEB-mediated autophagy rescues midbrain dopamine neurons from -synuclein toxicity
- (2013) M. Decressac et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy
- (2012) Jorge L. Ruas et al. CELL
- SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
- (2012) Nathan L. Price et al. Cell Metabolism
- The Role of PGC-1α in the Pathogenesis of Neurodegenerative Disorders
- (2012) Krisztina Rona-Voros et al. CURRENT DRUG TARGETS
- AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells
- (2012) L. Fassina et al. EUROPEAN JOURNAL OF HISTOCHEMISTRY
- Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson’s disease
- (2012) Almas Siddiqui et al. FREE RADICAL BIOLOGY AND MEDICINE
- Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset
- (2012) Eliana Marisa Ramos et al. HUMAN GENETICS
- A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset†
- (2012) Selma M. Soyal et al. HUMAN MOLECULAR GENETICS
- Sustained expression of PGC-1 in the rat nigrostriatal system selectively impairs dopaminergic function
- (2012) C. Ciron et al. HUMAN MOLECULAR GENETICS
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- PGC-1 Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function
- (2012) T. Tsunemi et al. Science Translational Medicine
- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
- (2011) Joo-Ho Shin et al. CELL
- Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease
- (2011) Giuseppa Mudò et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
- (2011) Ashu Johri et al. HUMAN MOLECULAR GENETICS
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis
- (2011) Wei Zhao et al. Molecular Neurodegeneration
- Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease
- (2011) Hong Van B Che et al. Molecular Neurodegeneration
- PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model
- (2011) Huiyun Liang et al. MUSCLE & NERVE
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effect of exercise intensity and AICAR on isoform-specific expressions of murine skeletal muscle PGC-1α mRNA: a role of β2-adrenergic receptor activation
- (2010) Miki Tadaishi et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Oxidative Stress in Parkinson's Disease
- (2010) Chun Zhou et al. Annals of the New York Academy of Sciences
- Mutations in cytoplasmic dynein lead to a Huntington's disease-like defect in energy metabolism of brown and white adipose tissues
- (2010) Judith Eschbach et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease
- (2010) Daniel J. Ho et al. EXPERIMENTAL NEUROLOGY
- Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity
- (2010) Karin M. Danzer et al. FASEB JOURNAL
- A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons
- (2010) Kerstin E. Braunstein et al. HUMAN MOLECULAR GENETICS
- Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma
- (2010) Ming-Chang Chiang et al. HUMAN MOLECULAR GENETICS
- Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation
- (2010) R. K. Chaturvedi et al. HUMAN MOLECULAR GENETICS
- PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
- (2010) B. Zheng et al. Science Translational Medicine
- PGC-1α-induced improvements in skeletal muscle metabolism and insulin sensitivityThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.
- (2009) Arend Bonen Applied Physiology Nutrition and Metabolism
- Impaired PGC-1α function in muscle in Huntington's disease
- (2009) Rajnish K. Chaturvedi et al. HUMAN MOLECULAR GENETICS
- PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons
- (2009) Przemyslaw Wareski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Seeding induced by α-synuclein oligomers provides evidence for spreading of α-synuclein pathology
- (2009) Karin M. Danzer et al. JOURNAL OF NEUROCHEMISTRY
- Brain-Permeable Small-Molecule Inhibitors of Hsp90 Prevent -Synuclein Oligomer Formation and Rescue -Synuclein-Induced Toxicity
- (2009) P. Putcha et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The gene coding for PGC-1α modifies age at onset in Huntington's Disease
- (2009) Patrick Weydt et al. Molecular Neurodegeneration
- PGC-1alpha as modifier of onset age in Huntington disease
- (2009) Elahe Taherzadeh-Fard et al. Molecular Neurodegeneration
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exogenous -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
- (2009) K. C. Luk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oxidative Stress Involvement in α-Synuclein Oligomerization in Parkinson's Disease Cybrids
- (2008) A. Raquel Esteves et al. ANTIOXIDANTS & REDOX SIGNALING
- Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis
- (2008) Rebecca Banerjee et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitochondria in the aetiology and pathogenesis of Parkinson's disease
- (2008) Anthony HV Schapira LANCET NEUROLOGY
- Formation of Toxic Oligomeric α-Synuclein Species in Living Cells
- (2008) Tiago Fleming Outeiro et al. PLoS One
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started