Innate defense regulator peptide 1018 protects against perinatal brain injury

Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain

(2013) Satoshi Imai et al.   BRAIN

M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia

(2013) Amy M Smith et al.   Journal of Neuroinflammation

Neuroprotection of Interleukin-6 Against NMDA-induced Neurotoxicity is Mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT Signaling Pathways

(2012) Xiao-Xia Fang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Hypoxia-Ischemia Upregulates TRAIL and TRAIL Receptors in the Immature Rat Brain

(2012) Zhiheng Huang et al.   DEVELOPMENTAL NEUROSCIENCE

CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species

(2012) Yee Andy Yeo et al.   Journal of Neuroinflammation

Modulating immunity as a therapy for bacterial infections

(2012) Robert E. W. Hancock et al.   NATURE REVIEWS MICROBIOLOGY

CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia

(2012) Emika Toyomitsu et al.   Purinergic Signalling

Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in a Preclinical Model of Severe Malaria

(2012) A. H. Achtman et al.   Science Translational Medicine

Delayed VEGF Treatment Enhances Angiogenesis and Recovery After Neonatal Focal Rodent Stroke

(2012) M. Dzietko et al.   Translational Stroke Research

Opposite effect of inflammation on subventricular zone versus hippocampal precursors in brain injury

(2011) Matthew V. Covey et al.   ANNALS OF NEUROLOGY

Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep

(2011) Justin M. Dean et al.   ANNALS OF NEUROLOGY

Systemic inflammation disrupts the developmental program of white matter

(2011) Géraldine Favrais et al.   ANNALS OF NEUROLOGY

Targeting the p53 pathway to protect the neonatal ischemic brain

(2011) Cora H. Nijboer et al.   ANNALS OF NEUROLOGY

Inflammation during fetal and neonatal life: Implications for neurologic and neuropsychiatric disease in children and adults

(2011) Henrik Hagberg et al.   ANNALS OF NEUROLOGY

Glucocorticoid-induced TNF receptor-triggered T cells are key modulators for survival/death of neural stem/progenitor cells induced by ischemic stroke

(2011) M Takata et al.   CELL DEATH AND DIFFERENTIATION

Suppression of Etk/Bmx Protects against Ischemic Brain Injury

(2011) Kai-Yun Chen et al.   CELL TRANSPLANTATION

Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke

(2011) J. V. Faustino et al.   JOURNAL OF NEUROSCIENCE

Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation

(2011) H. J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Studies of a Peptide with Immune Modulating and Direct Antimicrobial Activity

(2010) Michal Wieczorek et al.   CHEMISTRY & BIOLOGY

Regulation of MyD88 Aggregation and the MyD88-dependent Signaling Pathway by Sequestosome 1 and Histone Deacetylase 6

(2010) Takeshi Into et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Necrostatin Decreases Oxidative Damage, Inflammation, and Injury after Neonatal HI

(2010) Frances J Northington et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System

(2010) R. Khorooshi et al.   JOURNAL OF IMMUNOLOGY

Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment

(2010) Anastasia Nijnik et al.   JOURNAL OF IMMUNOLOGY

Stimulation of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) induces inflammatory activation of microglia in culture

(2010) Heehong Hwang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult

(2010) Giles S Kendall et al.   LABORATORY INVESTIGATION

Galectin-3 contributes to neonatal hypoxic–ischemic brain injury

(2010) Christina Doverhag et al.   NEUROBIOLOGY OF DISEASE

Mechanisms of hypothermic neuroprotection

(2010) Paul P. Drury et al.   Seminars in Fetal & Neonatal Medicine

Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro

(2009) J.M. Dean et al.   BRAIN BEHAVIOR AND IMMUNITY

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Phosphorylation of the Par Polarity Complex Protein Par3 at Serine 962 Is Mediated by Aurora A and Regulates Its Function in Neuronal Polarity

(2009) Mohammad R. Khazaei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner

(2009) X. Wang et al.   JOURNAL OF IMMUNOLOGY

A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity

(2009) Jason Kindrachuk et al.   VACCINE

Neonatal encephalitis and white matter injury: More than just inflammation?

(2008) Joseph J. Volpe   ANNALS OF NEUROLOGY

Ambivalent Aspects of Interleukin-6 in Cerebral Ischemia: Inflammatory versus Neurotrophic Aspects

(2008) Shigeaki Suzuki et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Thrombospondins 1 and 2 are Necessary for Synaptic Plasticity and Functional Recovery after Stroke

(2008) Jason Liauw et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Attenuation of Notch signaling promotes the differentiation of neural progenitors into neurons in the hippocampal CA1 region after ischemic injury

(2008) S. Oya et al.   NEUROSCIENCE

Outcomes of Safety and Effectiveness in a Multicenter Randomized, Controlled Trial of Whole-Body Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy

(2008) S. Shankaran et al.   PEDIATRICS

A Dual Role of the NF-κB Pathway in Neonatal Hypoxic-Ischemic Brain Damage

(2008) Cora H. Nijboer et al.   STROKE