M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia

The transcription factor PU.1 is critical for viability and function of human brain microglia

(2013) Amy M. Smith et al.   GLIA

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Phenotyping primary human microglia: Tight regulation of LPS responsiveness

(2012) Jeroen Melief et al.   GLIA

Immunology Taught by Humans

(2012) M. M. Davis   Science Translational Medicine

Macrophage colony-stimulating factor and its receptor signaling augment glycated albumin-induced retinal microglial inflammation in vitro

(2011) Wei Liu et al.   BMC CELL BIOLOGY

TREM-1 and DAP12 expression in monocytes of patients with severe psychiatric disorders. EGR3, ATF3 and PU.1 as important transcription factors

(2011) Karin Weigelt et al.   BRAIN BEHAVIOR AND IMMUNITY

Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences

(2011) Adam D. Hart et al.   BRAIN BEHAVIOR AND IMMUNITY

CCAAT/Enhancer-binding Protein β Inhibits Proliferation in Monocytic Cells by Affecting the Retinoblastoma Protein/E2F/Cyclin E Pathway but Is Not Directly Required for Macrophage Morphology

(2011) Romina Gutsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β

(2011) Marco Straccia et al.   Journal of Neuroinflammation

Differences in Origin of Reactive Microglia in Bone Marrow Chimeric Mouse and Rat After Transient Global Ischemia

(2011) Kate L. Lambertsen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

C/EBPβ expression in activated microglia in amyotrophic lateral sclerosis

(2011) Tony Valente et al.   NEUROBIOLOGY OF AGING

Distinct migratory and cytokine responses of human microglia and macrophages to ATP

(2010) Caroline Lambert et al.   BRAIN BEHAVIOR AND IMMUNITY

IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation

(2010) T Chihara et al.   CELL DEATH AND DIFFERENTIATION

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

(2010) Ilaria Marigo et al.   IMMUNITY

CSF-1, IGF-1, and the control of postnatal growth and development

(2010) Deborah J. Gow et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage-colony stimulating factor as an inducer of microglial proliferation in axotomized rat facial nucleus

(2010) Shinichi Yamamoto et al.   JOURNAL OF NEUROCHEMISTRY

Exploring the relationship of macrophage colony-stimulating factor levels on neuroaxonal metabolism and cognition during chronic human immunodeficiency virus infection

(2010) Margaret R Lentz et al.   JOURNAL OF NEUROVIROLOGY

Why mesial temporal lobe epilepsy with hippocampal sclerosis is progressive: Uncontrolled inflammation drives disease progression?

(2010) Tianhua Yang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures

(2010) Hannah M. Gibbons et al.   NEUROBIOLOGY OF DISEASE

Immunohistochemical characterization of microglia in Nasu-Hakola disease brains

(2010) Jun-ichi Satoh et al.   NEUROPATHOLOGY

Valproic acid enhances microglial phagocytosis of amyloid-β1–42

(2010) A.M. Smith et al.   NEUROSCIENCE

Changing Face of Microglia

(2010) M. B. Graeber   SCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Powerful beneficial effects of macrophage colony-stimulating factor on  -amyloid deposition and cognitive impairment in Alzheimer's disease

(2009) V. Boissonneault et al.   BRAIN

Effects of macrophage colony-stimulating factor on microglial responses to lipopolysaccharide and beta amyloid

(2009) Sharmili Vidyadaran et al.   CELLULAR IMMUNOLOGY

Cooperation between PU.1 and CAAT/Enhancer-binding Protein β Is Necessary to Induce the Expression of the MD-2 Gene

(2009) Pierre Tissières et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

(2009) Karel Otero et al.   NATURE IMMUNOLOGY

Immune Proteins in Brain Development and Synaptic Plasticity

(2009) Lisa M. Boulanger   NEURON

Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce Hsp70 protein

(2008) Xinhua Zhan et al.   BRAIN RESEARCH

THOC5 couples M-CSF receptor signaling to transcription factor expression

(2008) Louise Carney et al.   CELLULAR SIGNALLING

CCAAT/enhancer binding protein   deficiency provides cerebral protection following excitotoxic injury

(2008) M. Cortes-Canteli et al.   JOURNAL OF CELL SCIENCE

High-content analysis in neuroscience

(2008) Mike Dragunow   NATURE REVIEWS NEUROSCIENCE

PU.1 and C/EBP /  convert fibroblasts into macrophage-like cells

(2008) R. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

(2008) H. Lin et al.   SCIENCE