Anesthetic Propofol Causes Glycogen Synthase Kinase-3β-regulated Lysosomal/Mitochondrial Apoptosis in Macrophages

The effects of propofol on hippocampal caspase-3 and Bcl-2 expression following forebrain ischemia–reperfusion in rats

(2010) Jun Li et al.   BRAIN RESEARCH

L-Arginine Enhances Nitrative Stress and Exacerbates Tumor Necrosis Factor-α Toxicity to Human Endothelial Cells in Culture: Prevention by Propofol

(2010) Zhengyuan Xia et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Lithium Protects against Anesthesia-induced Developmental Neuroapoptosis

(2009) Megan M. W. Straiko et al.   ANESTHESIOLOGY

Inhibiting glycogen synthase kinase-3 reduces endotoxaemic acute renal failure by down-regulating inflammation and renal cell apoptosis

(2009) Y Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glycogen synthase kinase 3: more than a namesake

(2009) Geetha Vani Rayasam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB

(2009) Wen-Ta Chiu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells

(2009) Wei-Ching Huang et al.   IMMUNOLOGY

Propofol protects against hydrogen peroxide-induced oxidative stress and cell dysfunction in human umbilical vein endothelial cells

(2009) Jiawei Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Glycogen Synthase Kinase-3 and Omi/HtrA2 Induce Annexin A2 Cleavage followed by Cell Cycle Inhibition and Apoptosis

(2009) Chi-Yun Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Effects of propofol on pro-inflammatory cytokines and nuclear factor kappaB during polymicrobial sepsis in rats

(2009) Xue-Min Song et al.   MOLECULAR BIOLOGY REPORTS

JNK mediates UVB-induced apoptosis upstream lysosomal membrane permeabilization and Bcl-2 family proteins

(2008) Cecilia Bivik et al.   APOPTOSIS

Dose-dependent protective effect of propofol against mitochondrial dysfunction in ischaemic/reperfused rat heart: role of cardiolipin

(2008) H Shao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3  Inactivation

(2008) T. M. Thornton et al.   SCIENCE

Propofol pretreatment attenuates LPS-induced granulocyte–macrophage colony-stimulating factor production in cultured hepatocytes by suppressing MAPK/ERK activity and NF-κB translocation

(2008) B JAWAN et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY