New Insights to Clathrin and Adaptor Protein 2 for the Design and Development of Therapeutic Strategies

Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP–SorLA Interaction

(2015) Luca Rosario La Rosa et al.   Frontiers in Cellular Neuroscience

An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform

(2014) Ishita Parikh et al.   Molecular Neurodegeneration

Trafficking regulation of proteins in Alzheimer’s disease

(2014) Shangtong Jiang et al.   Molecular Neurodegeneration

AP2 controls clathrin polymerization with a membrane-activated switch

(2014) B. T. Kelly et al.   SCIENCE

A new molecular explanation for age-related neurodegeneration: The Tyr682 residue of amyloid precursor protein

(2013) Carmela Matrone   BIOESSAYS

Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes

(2013) Ingyu Kim et al.   JOURNAL OF CELL BIOLOGY

PICALM Gene rs3851179 Polymorphism Contributes to Alzheimer’s Disease in an Asian Population

(2013) Guiyou Liu et al.   NEUROMOLECULAR MEDICINE

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

(2013) Y. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance

(2012) Carmela Matrone et al.   AGING CELL

MS Data Miner: A web-based software tool to analyze, compare, and share mass spectrometry protein identifications

(2012) Thomas F. Dyrlund et al.   PROTEOMICS

Clathrin-mediated endocytic proteins are upregulated in the cortex of the Tg2576 mouse model of Alzheimer’s disease-like amyloid pathology

(2011) Rhian S. Thomas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling

(2011) C. Matrone et al.   JOURNAL OF NEUROSCIENCE

Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer's disease in a southern Chinese population

(2011) Lu Hua Chen et al.   NEUROBIOLOGY OF AGING

Intracellular Trafficking of the Amyloid β-Protein Precursor (APP) Regulated by Novel Function of X11-Like

(2011) Yuhki Saito et al.   PLoS One

Functional Links Between A  Toxicity, Endocytic Trafficking, and Alzheimer's Disease Risk Factors in Yeast

(2011) S. Treusch et al.   SCIENCE

Neuronal activity and the expression of clathrin-assembly protein AP180

(2010) Fangbai Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clathrin-mediated endocytosis and Alzheimer's disease: An update

(2009) Fangbai Wu et al.   AGEING RESEARCH REVIEWS

The clathrin assembly protein AP180 regulates the generation of amyloid-β peptide

(2009) Fangbai Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS