Article
Chemistry, Multidisciplinary
Francesca Ferraris, Carlos Adelantado, Andrea Raggi, Sara Savini, Mohammed Zougagh, Angel Rios, Francesco Cubadda
Summary: A method using ICP-MS and microwave-assisted acid digestion was developed for the determination of total titanium in food and food supplements. The method was successfully validated and enables rapid screening of food samples for the presence of TiO2 particles.
Article
Chemistry, Multidisciplinary
Johanna Noireaux, Sara Lopez-Sanz, Janja Vidmar, Manuel Correia, Laurent Devoille, Paola Fisicaro, Katrin Loeschner
Summary: The study characterized the food additive E171 using triple-quadrupole and high-resolution inductively coupled plasma-mass spectrometry (ICP-MS), and added TiO2 particles to a calcium-rich matrix, showing that both ICP-MS techniques were efficient in determining particle size distributions. The combination of spICP-MS with microscopy and TiO2 recovery validated the methods and identified aggregated/agglomerated particles in a sample, with recoveries over 60% for the TiO2 powder and remaining food products.
JOURNAL OF NANOPARTICLE RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Zaual A. Temerdashev, Olga A. Galitskaya, Mikhail A. Bolshov
Summary: This study discusses the features and methods involved in determining the sizes of titanium dioxide nanoparticles in cosmetic samples using single particle inductively coupled plasma mass spectrometry (SP-ICP-MS). A correction procedure for the background signal is proposed, which allows for the removal of background signals from the sample signal distribution, resulting in the determination of the distribution of nanoparticle signals in cosmetic product samples.
Article
Chemistry, Analytical
Maria Vanesa Taboada-Lopez, Dorota Bartczak, Susana Cuello-Nunez, Heidi Goenaga-Infante, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: A method using AF4 coupled with UV-vis and ICP-MS has been developed for detecting and quantifying Ag NPs in bivalve molluscs, showing an interaction between Ag NPs and proteins, as well as different size distributions of Ag NPs in selected samples. Confirmation of Ag NPs presence in enzymatic extracts was demonstrated by SEM after an oxidative pre-treatment.
Article
Developmental Biology
J. N. D'Errico, C. Doherty, J. J. Reyes George, B. Buckley, P. A. Stapleton
Summary: This study evaluated the distribution of inhaled titanium dioxide nanoparticles from maternal lung to maternal and fetal systemic tissues in pregnant rats and found extrapulmonary distribution of titanium to various maternal organs during pregnancy. The study also identified systemic distribution and placental accumulation of titanium after nano-TiO2 aerosol inhalation in a pregnancy model, arousing concerns for poor air quality for pregnant women and possible contributions to adverse pregnancy outcomes.
Article
Biochemistry & Molecular Biology
Jorge Toledano-Serrabona, Diogo Pompeu de Moraes, Sara Gonzalez-Morales, M. Angeles Sanchez-Garces, Jorg Bettmer, Maria Montes-Bayon, Mario Corte-Rodriguez
Summary: This study investigates the presence of Ti, Al, and V metal ions and Ti nanoparticles in rat organs after implantoplasty surgery. The authors developed optimized methods for sample preparation and analysis, using microsampling inserts and enzymatic digestion, to quantify the metal contents. The results show a significant increase in Ti concentrations in various tissues of experimental animals compared to the control group, particularly in the brain and spleen. Additionally, Ti-containing nanoparticles were observed in all tissues analyzed.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2023)
Article
Chemistry, Analytical
Maria Vanesa Taboada-Lopez, Baltazar Hiram Leal-Martinez, Raquel Dominguez-Gonzalez, Pilar Bermejo-Barrera, Pablo Taboada-Antelo, Antonio Moreda-Pineiro
Summary: Titanium dioxide nanoparticles and silver nanoparticles are extensively used in various industries and may unintentionally enter the human gastrointestinal tract through food and water. In vitro digestion studies were conducted to determine the bioaccessibility of these nanoparticles in shellfish, as well as their transport through the gastrointestinal epithelial barrier model.
Article
Chemistry, Applied
Maria Hayder, Maciej Trzaskowski, Lena Ruzik
Summary: The study investigated the influence of different food components on metallic nanoparticles fate during in vitro gastrointestinal simulation, revealing that food matrix components significantly impact the size, shape, and behavior of nanoparticles. Possible explanations for the influence of main nutrient groups like lipids, protein, salts, saccharides, and vitamins on nanoparticles have been proposed.
Article
Chemistry, Physical
Alejandra Romero-Moran, Jose L. Sanchez-Salas, Joel Molina-Reyes
Summary: The study established the influence of the crystalline phase and agglomeration degree of TiO2 nanoparticles on photocatalytic hydroxyl radical formation and bacterial inactivation in TiO2/SiO2 composite coatings. A relationship between hydroxyl radicals' formation and charge carrier transfer mechanism between defect levels in SiO2 and TiO2 embedded nanoparticles was established through a simple spectroscopic method. This correlation complements the lack of mechanisms behind the photocatalytic activity in TiO2/SiO2 composites.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2021)
Article
Chemistry, Analytical
Wanida Suwanroek, Jitapa Sumranjit, Tuksadon Wutikhun, Atitaya Siripinyanond
Summary: An analytical method based on single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) was developed to study the release of ZnO nanoparticles from fabric face mask samples upon washing. The results showed that the release of ZnO nanoparticles from the mask samples was influenced by the detergent concentration.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Environmental Sciences
Janja Vidmar, Tea Zuliani, Radmila Milacic, Janez Scancar
Summary: This study reports for the first time the levels of anthropogenic titanium dioxide nanoparticles (TiO(2)NPs) in different compartments of the Sava River and identifies urban, agricultural, and/or industrial activities as the main sources of these particles. The results also highlight the significant influence of hydrological conditions and sediment composition on the levels of TiO(2)NPs in river water.
Article
Environmental Sciences
Chen Wang, Wei Wei, Giorgio Mannina, Xiaohu Dai, Bing-Jie Ni
Summary: This study found that aerobic digestion with TiO2 NPs can enhance the degradation of volatile solids and the production of total inorganic nitrogen. Microbial analysis showed that TiO2 NPs contribute to the accumulation of specific microbes involved in the degradation of organic substances and the conversion of nitrogen compounds. Further mechanistic studies indicated that TiO2 NPs promote the solubilization of waste activated sludge and the degradation of recalcitrant substances, converting them into digestible substrates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Huiming Huang, Brian Grajeda, Cameron C. Ellis, Igor L. Estevao, Wen-Yee Lee
Summary: This study investigated the combined toxicity of bisphenol A (BPA) and titanium dioxide nanoparticles (TiO2-NPs) on Arabidopsis thaliana. The results showed that both compounds had effects on plant growth, leading to changes in root length and branching. The study also revealed the plant's adaptive mechanisms to stress caused by BPA and TiO2-NPs through up-regulation of certain proteins related to resource transportation and energy metabolism. Therefore, applying biosolids as fertilizer to soil could be considered as a sustainable practice.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Review
Chemistry, Analytical
Andrei R. Timerbaev, Olga Kuznetsova, Bernhard K. Keppler
Summary: This article critically analyzes the current and emerging capabilities of analytical methods for the analysis and characterization of ENPs in seawater in the past decade, focusing on the importance of experimental strategies to avoid the high-salt matrix effect and enrich the nanoparticulate fraction before analysis. The methods rely on elemental mass spectrometry and single-particle mode to characterize the transformation of ENPs in seawater.
Article
Food Science & Technology
Otmar Geiss, Ivana Bianchi, Chiara Senaldi, Guillaume Bucher, Eveline Verleysen, Nadia Waegeneers, Frederic Brassinne, Jan Mast, Katrin Loeschner, Janja Vidmar, Federica Aureli, Francesco Cubadda, Andrea Raggi, Francesca Iacoponi, Ruud Peters, Anna Undas, Alexandra Mueller, Ann-Katrin Meinhardt, Elke Walz, Volker Graef, Josefa Barrero-Moreno
Summary: A single-particle inductively coupled plasma mass spectrometry method was developed to determine the size distribution and concentration of titanium dioxide particles in food, showing good repeatability and reproducibility in an interlaboratory comparison study. This promising technique could potentially be a standardized method for assessing engineered nanomaterials in food products.
Article
Limnology
Beatriz Ferreira Araujo, Holger Hintelmann, Brian Dimock, Rodrigo de Lima Sobrinho, Marcelo Correa Bernardes, Marcelo Gomes de Almeida, Alex Krusche, Thiago Pessanha Rangel, Fabiano Thompson, Carlos Eduardo de Rezende
LIMNOLOGY AND OCEANOGRAPHY
(2018)
Article
Chemistry, Analytical
Carluvy Baptista-Salazar, Holger Hintelmann, Harald Biester
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2018)
Article
Engineering, Environmental
Jonathan D. Martin, Paul C. Frost, Holger Hintelmann, Karla Newman, Michael J. Paterson, Lauren Hayhurst, Michael D. Rennie, Marguerite A. Xenopoulos, Viviane Yargeau, Chris D. Metcalfe
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2018)
Article
Engineering, Environmental
Fei Dang, Yuan-Zhen Chen, Ying-Nan Huang, Holger Hintelmann, You-Bin Si, Dong-Mei Zhou
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2019)
Article
Environmental Sciences
Maria Teresa Cabrita, Bernardo Duarte, Rute Cesario, Ricardo Mendes, Holger Hintelmann, Kevin Eckey, Brian Dimock, Isabel Cacador, Joao Canario
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Environmental Sciences
Marko Strok, Pascale Anabelle Baya, Doerthe Dietrich, Brian Dimock, Holger Hintelmann
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Engineering, Environmental
Wenli Tang, Holger Hintelmann, Baohua Gu, Xinbin Feng, Yurong Liu, Yuxi Gao, Jiating Zhao, Huike Zhu, Pei Lei, Huan Zhong
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2019)
Article
Multidisciplinary Sciences
Nives Ogrinc, Holger Hintelmann, Joze Kotnik, Milena Horvatl, Nicola Pirrone
SCIENTIFIC REPORTS
(2019)
Article
Environmental Sciences
Pablo A. Perez, Holger Hintelmann, Gabriela Lobos, Manuel A. Bravo
Article
Chemistry, Multidisciplinary
Min Li, Hai-Long Liu, Fei Dang, Holger Hintelmann, Bin Yin, Dongmei Zhou
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2020)
Article
Environmental Sciences
Anna K. Karjalainen, Johanna Salmelin, Brian Dimock, Holger Hintelmann
WATER AIR AND SOIL POLLUTION
(2020)
Article
Environmental Sciences
Beatriz Bento, Holger Hintelmann, Margarida Correia dos Santos, Rute Cesario, Joao Canario
Summary: Research found that Deception Island in Antarctica is an active volcano, with volcanic eruptions being one of the reasons for high mercury concentrations. Higher levels of total mercury and monomethylmercury were found in this ecosystem, with biotic methylation rates in water being significantly higher and abiotic methylation playing an important role.
MARINE POLLUTION BULLETIN
(2021)
Article
Multidisciplinary Sciences
Paul J. Blanchfield, John W. M. Rudd, Lee E. Hrenchuk, Marc Amyot, Christopher L. Babiarz, Ken G. Beaty, R. A. Drew Bodaly, Brian A. Branfireun, Cynthia C. Gilmour, Jennifer A. Graydon, Britt D. Hall, Reed C. Harris, Andrew Heyes, Holger Hintelmann, James P. Hurley, Carol A. Kelly, David P. Krabbenhoft, Steve E. Lindberg, Robert P. Mason, Michael J. Paterson, Cheryl L. Podemski, Ken A. Sandilands, George R. Southworth, Vincent L. St Louis, Lori S. Tate, Michael T. Tate
Summary: The 15-year experiment conducted to reduce fish MeHg concentrations by decreasing Hg additions to a boreal lake and its watershed demonstrated that any reduction in Hg loadings to lakes, whether from direct deposition or runoff, will have immediate benefits to fish consumers.
Article
Environmental Sciences
Audrey Campeau, Karin Eklof, Anne L. Soerensen, Staffan Akerblom, Shengliu Yuan, Holger Hintelmann, Magdalena Bieroza, Stephan Kohler, Christian Zdanowicz
Summary: The Arctic environment contains a complex mosaic of mercury and carbon reservoirs, some of which are destabilizing rapidly due to climate warming. Measurements and analyses of mercury and carbon concentrations in river water revealed major differences in the sources of particulate and dissolved riverine mercury, despite a common positive association with older material.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Neusa Figueiredo, Maria Luisa Serralheiro, Joao Canario, Aida Duarte, Holger Hintelmann, Cristina Carvalho
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2018)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)