Enhancing Human Islet Transplantation by Localized Release of Trophic Factors From PLG Scaffolds

Dual factor delivery of CXCL12 and Exendin-4 for improved survival and function of encapsulated beta cells under hypoxic conditions

(2013) Stephanie Duncanson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Collagen IV-Modified Scaffolds Improve Islet Survival and Function and Reduce Time to Euglycemia

(2013) Woon Teck Yap et al.   TISSUE ENGINEERING PART A

Exenatide extended-release; clinical trials, patient preference, and economic considerations

(2013) Sheila Doggrell   Patient Preference and Adherence

Exendin-4 Increases the Expression of Hypoxia-Inducible Factor-1α in Rat Islets and Preserves the Endocrine Cell Volume of Both Free and Macroencapsulated Islet Grafts

(2012) Xiaohui Jia et al.   CELL TRANSPLANTATION

Molecularly Engineered Islet Cell Clusters for Diabetes Mellitus Treatment

(2012) Simmyung Yook et al.   CELL TRANSPLANTATION

Porous Scaffolds Support Extrahepatic Human Islet Transplantation, Engraftment, and Function in Mice

(2012) Romie F. Gibly et al.   CELL TRANSPLANTATION

Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010

(2012) F. B. Barton et al.   DIABETES CARE

An Update in Incretin-Based Therapy: A Focus on Glucagon-Like Peptide-1 Receptor Agonists

(2012) Krystal L. Edwards et al.   Diabetes Technology & Therapeutics

Functional enhancement of beta cells in transplanted pancreatic islets by secretion signal peptide-linked exendin-4 gene transduction

(2012) Jee-Heon Jeong et al.   JOURNAL OF CONTROLLED RELEASE

Permanent protection of PLG scaffold transplanted allogeneic islet grafts in diabetic mice treated with ECDI-fixed donor splenocyte infusions

(2011) Taba Kheradmand et al.   BIOMATERIALS

Extrahepatic islet transplantation with microporous polymer scaffolds in syngeneic mouse and allogeneic porcine models

(2011) Romie F. Gibly et al.   BIOMATERIALS

Anti-Inflammatory Properties of Exenatide in Human Pancreatic Islets

(2011) S. R. Cechin et al.   CELL TRANSPLANTATION

Encapsulation of Exenatide in Poly-(d,l-Lactide-Co-Glycolide) Microspheres Produced an Investigational Long-Acting Once-Weekly Formulation for Type 2 Diabetes

(2011) Mary Beth DeYoung et al.   Diabetes Technology & Therapeutics

Preparation, Characterization, and Pharmacodynamics of Exenatide-Loaded Poly(DL-lactic-co-glycolic acid) Microspheres

(2010) Bin Liu et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Encapsulation of Pancreatic Islets Within Nano-Thin Functional Polyethylene Glycol Coatings for Enhanced Insulin Secretion

(2010) Seda Kizilel et al.   TISSUE ENGINEERING PART A

Glucagon-Like Peptide-1 Functionalized PEG Hydrogels Promote Survival and Function of Encapsulated Pancreatic β-Cells

(2009) Chien-Chi Lin et al.   BIOMACROMOLECULES

The reversal of hyperglycaemia in diabetic mice using PLGA scaffolds seeded with islet-like cells derived from human embryonic stem cells

(2009) Gen-hong Mao et al.   BIOMATERIALS

GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting apoptosis

(2008) Kentaro Toyoda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sequential release of bioactive IGF-I and TGF-β1 from PLGA microsphere-based scaffolds

(2008) Ana Jaklenec et al.   BIOMATERIALS

Layered PLG scaffolds for in vivo plasmid delivery

(2008) Christopher B. Rives et al.   BIOMATERIALS

Optimal implantation site for pancreatic islet transplantation

(2008) S. Merani et al.   BRITISH JOURNAL OF SURGERY

The Choice of Anatomical Site for Islet Transplantation

(2008) Dirk J. Van Der Windt et al.   CELL TRANSPLANTATION

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice

(2008) J. Agudo et al.   DIABETOLOGIA

Extracellular Matrix Protein-Coated Scaffolds Promote the Reversal of Diabetes After Extrahepatic Islet Transplantation

(2008) David M. Salvay et al.   TRANSPLANTATION

The ATP/DNA Ratio Is a Better Indicator of Islet Cell Viability Than the ADP/ATP Ratio

(2008) T.M. Suszynski et al.   TRANSPLANTATION PROCEEDINGS

How to achieve sustained and complete protein release from PLGA-based microparticles?

(2007) A. Giteau et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS