A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response

Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans

(2017) Christopher F. Bennett et al.   PLoS Genetics

PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila

(2017) Martin Borch Jensen et al.   eLife

The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases

(2016) Li Li et al.   Oncotarget

Interventions to Slow Aging in Humans: Are We Ready?

(2015) Valter D. Longo et al.   AGING CELL

Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity

(2015) Anton Danilov et al.   Oncotarget

Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import

(2014) Chong He et al.   PLoS Genetics

A Genetic Program Promotes C. elegans Longevity at Cold Temperatures via a Thermosensitive TRP Channel

(2013) Rui Xiao et al.   CELL

Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway

(2013) Qin-Li Wan et al.   EXPERIMENTAL GERONTOLOGY

The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease

(2013) V. Jovaisaite et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

AMPK: mediating the metabolic effects of salicylate-based drugs?

(2013) Gregory R. Steinberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans

(2013) Louis R. Lapierre et al.   Nature Communications

Aspirin Inhibits Oxidant Stress, Reduces Age-Associated Functional Declines, and Extends Lifespan of Caenorhabditis elegans

(2012) Srinivas Ayyadevara et al.   ANTIOXIDANTS & REDOX SIGNALING

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

(2011) Antero Salminen et al.   AGEING RESEARCH REVIEWS

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

(2011) Jenni Durieux et al.   CELL

drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans

(2010) Tsui-Ting Ching et al.   AGING CELL

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

(2008) Randy  Strong et al.   AGING CELL

Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes

(2007) George L. Sutphin et al.   EXPERIMENTAL GERONTOLOGY