Astrocyte-derived retinoic acid: a novel regulator of blood–brain barrier function in multiple sclerosis

Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation

(2014) Debayon Paul et al.   Journal of Neuroinflammation

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Retinoic Acid Induces Blood-Brain Barrier Development

(2013) M. R. Mizee et al.   JOURNAL OF NEUROSCIENCE

All-Trans-Retinoic Acid Rescues Neurons After Global Ischemia by Attenuating Neuroinflammatory Reactions

(2013) Jeong Hwan Kim et al.   NEUROCHEMICAL RESEARCH

Estrogen Receptor and PI3K/Akt Signaling Pathway Involvement in S-(-)Equol-Induced Activation of Nrf2/ARE in Endothelial Cells

(2013) Ting Zhang et al.   PLoS One

Fingolimod attenuates ceramide-induced blood–brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes

(2012) Ruben van Doorn et al.   ACTA NEUROPATHOLOGICA

Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

(2012) Maarten E. Witte et al.   ACTA NEUROPATHOLOGICA

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Astrocytes as a regulated source of retinoic acid for the brain

(2012) Kirsty D. Shearer et al.   GLIA

Expression of retinoid X receptor beta is induced in astrocytes during corpus callosum demyelination

(2012) René König et al.   JOURNAL OF CHEMICAL NEUROANATOMY

The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis

(2012) Shujun Ge et al.   Journal of Neuroinflammation

Retinol levels are associated with magnetic resonance imaging outcomes in multiple sclerosis

(2012) Kristin I Løken-Amsrud et al.   Multiple Sclerosis Journal

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

IFN-γ Signaling to Astrocytes Protects from Autoimmune Mediated Neurological Disability

(2012) Claudia Hindinger et al.   PLoS One

Natalizumab

(2012) Richard Rudick et al.   JAMA Neurology

Classical immunomodulatory therapy in multiple sclerosis: how it acts, how it works

(2011) Amélia Mendes et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

The molecular basis of neurodegeneration in multiple sclerosis

(2011) Hans Lassmann et al.   FEBS LETTERS

Gp130-Dependent Astrocytic Survival Is Critical for the Control of Autoimmune Central Nervous System Inflammation

(2011) F. Haroon et al.   JOURNAL OF IMMUNOLOGY

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Radical changes in multiple sclerosis pathogenesis

(2010) Jack van Horssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Adenosine triphosphate-binding cassette transporters mediate chemokine (C-C motif) ligand 2 secretion from reactive astrocytes: relevance to multiple sclerosis pathogenesis

(2010) Gijs Kooij et al.   BRAIN

Multiple Retinol and Retinal Dehydrogenases Catalyze All-trans-retinoic Acid Biosynthesis in Astrocytes

(2010) Chao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

Synthetic Retinoid AM80 Inhibits Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis

(2009) Christian Klemann et al.   AMERICAN JOURNAL OF PATHOLOGY

Nrf2 promotes neuronal cell differentiation

(2009) Fei Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling

(2009) Hiroshi Katsuki et al.   JOURNAL OF NEUROCHEMISTRY

Reactive Astrocytes Form Scar-Like Perivascular Barriers to Leukocytes during Adaptive Immune Inflammation of the CNS

(2009) R. R. Voskuhl et al.   JOURNAL OF NEUROSCIENCE

Retinoic Acid Synthesis and Signaling during Early Organogenesis

(2008) Gregg Duester   CELL

Astrocytes in multiple sclerosis: A product of their environment

(2008) A. Nair et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protective effects of peroxiredoxin-1 at the injured blood–brain barrier

(2008) Gerty Schreibelt et al.   FREE RADICAL BIOLOGY AND MEDICINE

SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function

(2007) Ruud D. Fontijn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY