NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

Newly lesioned tissue in multiple sclerosis--a role for oxidative damage?

(2011) K. J. Smith   BRAIN

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

(2011) Ralf A. Linker et al.   BRAIN

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Arachidonyl trifluoromethyl ketone ameliorates experimental autoimmune encephalomyelitis via blocking peroxynitrite formation in mouse spinal cord white matter

(2011) Adam C. Vana et al.   EXPERIMENTAL NEUROLOGY

The molecular basis of neurodegeneration in multiple sclerosis

(2011) Hans Lassmann et al.   FEBS LETTERS

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Review: The architecture of inflammatory demyelinating lesions: implications for studies on pathogenesis

(2011) H. Lassmann   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Distinct role of nitric oxide and peroxynitrite in mediating oligodendrocyte toxicity in culture and in experimental autoimmune encephalomyelitis

(2011) S. Li et al.   NEUROSCIENCE

Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination

(2010) Rakhi Sharma et al.   ACTA NEUROPATHOLOGICA

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death

(2010) S. Veto et al.   BRAIN

Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions

(2010) Jack van Horssen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes

(2010) Iryna Ziabreva et al.   GLIA

Mitochondrial dysfunction: A potential link between neuroinflammation and neurodegeneration?

(2010) Maarten E. Witte et al.   MITOCHONDRION

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Molecular Changes in White Matter Adjacent to an Active Demyelinating Lesion in Early Multiple Sclerosis

(2009) Thomas Zeis et al.   BRAIN PATHOLOGY

Enhanced number and activity of mitochondria in multiple sclerosis lesions

(2009) Maarten E Witte et al.   JOURNAL OF PATHOLOGY

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation

(2009) Eva-Maria Nicolussi et al.   NEUROBIOLOGY OF DISEASE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

(2008) J. van Horssen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?

(2008) Helga E. de Vries et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

(2008) C. Cheret et al.   JOURNAL OF NEUROSCIENCE

Review: Mitochondria and disease progression in multiple sclerosis

(2008) D. Mahad et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Elevated myeloperoxidase activity in white matter in multiple sclerosis

(2008) Elizabeth Gray et al.   NEUROSCIENCE LETTERS

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

(2008) L. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated Activity and Microglial Expression of Myeloperoxidase in Demyelinated Cerebral Cortex in Multiple Sclerosis

(2007) Elizabeth Gray et al.   BRAIN PATHOLOGY