Casticin suppresses self-renewal and invasion of lung cancer stem-like cells from A549 cells through down-regulation of pAkt

CD133+ cancer stem cells in lung cancer 

(2013) Zhen Xu   Frontiers in Bioscience-Landmark

TGF-β1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133+ A549 cell fraction

(2013) V Tirino et al.   Cell Death & Disease

Aberrant expression of CD133 in non-small cell lung cancer and its relationship to vasculogenic mimicry

(2012) Shiwu Wu et al.   BMC CANCER

Characterization of sphere-forming cells with stem-like properties from the small cell lung cancer cell line H446

(2012) Xiaofei Qiu et al.   CANCER LETTERS

ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors

(2012) Cheng-Po Huang et al.   CANCER LETTERS

Testing the cancer stem cell hypothesis in melanoma: The clinics will tell

(2012) Olga Shakhova et al.   CANCER LETTERS

EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

(2012) Sandeep Singh et al.   Molecular Cancer

Elevated lipogenesis in epithelial stem-like cell confers survival advantage in ductal carcinoma in situ of breast cancer

(2012) P R Pandey et al.   ONCOGENE

Antagonism of miR-21 Reverses Epithelial-Mesenchymal Transition and Cancer Stem Cell Phenotype through AKT/ERK1/2 Inactivation by Targeting PTEN

(2012) Mingli Han et al.   PLoS One

Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

(2011) Junlin Li et al.   BMC CANCER

Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines

(2011) Lu Cao et al.   BMC GASTROENTEROLOGY

Casticin-induced apoptosis involves death receptor 5 upregulation in hepatocellular carcinoma cells

(2011) Jun Yang   WORLD JOURNAL OF GASTROENTEROLOGY

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Identification of CD133−/Telomeraselow Progenitor Cells in Glioblastoma-Derived Cancer Stem Cell Lines

(2010) Fabian Beier et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9

(2010) Dipak Sapkota et al.   EUROPEAN JOURNAL OF CANCER

Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like Properties

(2010) Elaine Lai-Han Leung et al.   PLoS One

Casticin induces leukemic cell death through apoptosis and mitotic catastrophe

(2009) Jia-Kun Shen et al.   ANNALS OF HEMATOLOGY

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1α up-regulation and MMP9 activation

(2008) Gang Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

(2008) A. Dubrovska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA