Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic colitis

Oral treatment with SEW2871, a sphingosine-1-phosphate type 1 receptor agonist, ameliorates experimental colitis in interleukin-10 gene deficient mice

(2014) J. Dong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Adalimumab prevents barrier dysfunction and antagonizes distinct effects of TNF-α on tight junction proteins and signaling pathways in intestinal epithelial cells

(2013) Andreas Fischer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anti-mouse CD52 monoclonal antibody ameliorates iron-deficient anaemia in IL-10 knockout mice

(2013) Honggang Wang et al.   BRITISH JOURNAL OF NUTRITION

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

(2013) Roosmarijn E. Vandenbroucke et al.   EMBO Molecular Medicine

TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis

(2013) Liping Su et al.   GASTROENTEROLOGY

Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation

(2013) M Vivinus-Nébot et al.   GUT

Sirolimus ameliorates inflammatory responses by switching the regulatory T/T helper type 17 profile in murine colitis

(2013) Hui Yin et al.   IMMUNOLOGY

TRAIL receptor deficiency sensitizes mice to dextran sodium sulphate-induced colitis and colitis-associated carcinogenesis

(2013) Jieqing Zhu et al.   IMMUNOLOGY

Iron Status, Anemia, and Plasma Erythropoietin Levels in Acute and Chronic Mouse Models of Colitis

(2013) Patsy R. Carter et al.   INFLAMMATORY BOWEL DISEASES

Increased Epithelial Permeability Is the Primary Cause for Bicarbonate Loss in Inflamed Murine Colon

(2013) Marina Juric et al.   INFLAMMATORY BOWEL DISEASES

Supplemental Naringenin Prevents Intestinal Barrier Defects and Inflammation in Colitic Mice

(2013) Tomoyo Azuma et al.   JOURNAL OF NUTRITION

Intestinal dysbacteriosis contributes to decreased intestinal mucosal barrier function and increased bacterial translocation

(2013) H. Wang et al.   LETTERS IN APPLIED MICROBIOLOGY

Aluminum enhances inflammation and decreases mucosal healing in experimental colitis in mice

(2013) G Pineton de Chambrun et al.   Mucosal Immunology

Bifidobacteria may be beneficial to intestinal microbiota and reduction of bacterial translocation in mice following ischaemia and reperfusion injury

(2012) Honggang Wang et al.   BRITISH JOURNAL OF NUTRITION

Complex Roles of Caspases in the Pathogenesis of Inflammatory Bowel Disease

(2012) Christoph Becker et al.   GASTROENTEROLOGY

Whatʼs the next best cytokine target in IBD?

(2012) Thomas T. MacDonald et al.   INFLAMMATORY BOWEL DISEASES

Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics

(2012) Nina A. Hering et al.   JOURNAL OF PHYSIOLOGY-LONDON

Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

(2012) Jeffrey A Cohen et al.   LANCET

Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

(2012) Alasdair J Coles et al.   LANCET

Human Peripheral Blood Mononuclear Cells Exhibit Heterogeneous CD52 Expression Levels and Show Differential Sensitivity to Alemtuzumab Mediated Cytolysis

(2012) Sambasiva P. Rao et al.   PLoS One

Estrogen receptor-β signaling modulates epithelial barrier function

(2011) Mirjam Looijer-van Langen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Activity of alemtuzumab monotherapy in treatment-naive, relapsed, and refractory severe acquired aplastic anemia

(2011) P. Scheinberg et al.   BLOOD

Epithelial inducible nitric oxide synthase causes bacterial translocation by impairment of enterocytic tight junctions via intracellular signals of Rho-associated kinase and protein kinase C zeta*

(2011) Li-Ling Wu et al.   CRITICAL CARE MEDICINE

Increase in the Tight Junction Protein Claudin-1 in Intestinal Inflammation

(2011) Lisa S. Poritz et al.   DIGESTIVE DISEASES AND SCIENCES

Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease

(2011) Michael Schumann et al.   GUT

Antimouse CD52 monoclonal antibody inhibits established spontaneous colitis in IL-10-deficient mice

(2011) W. M. Zhu et al.   INFLAMMATORY BOWEL DISEASES

The bone morphogenetic protein–hepcidin axis as a therapeutic target in inflammatory bowel disease

(2011) Lijian Wang et al.   INFLAMMATORY BOWEL DISEASES

New Pathogenic Paradigms in Inflammatory Bowel Disease

(2011) Antonio Di Sabatino et al.   INFLAMMATORY BOWEL DISEASES

IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease

(2011) Alessandra Geremia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

KSR1 Protects From Interleukin-10 Deficiency-Induced Colitis in Mice by Suppressing T-Lymphocyte Interferon-γ Production

(2010) Jeremy A. Goettel et al.   GASTROENTEROLOGY

Effects of T cell-induced colonic inflammation on epithelial barrier function†

(2010) Peter Suenaert et al.   INFLAMMATORY BOWEL DISEASES

Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity

(2010) Christopher R. Weber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial NF-κB Enhances Transmucosal Fluid Movement by Altering Tight Junction Protein Composition after T Cell Activation

(2009) Yueming Tang et al.   AMERICAN JOURNAL OF PATHOLOGY

Translating Inflammatory Bowel Disease Research into Clinical Medicine

(2009) Markus F. Neurath et al.   IMMUNITY

The suppressive effect of triptolide on chronic colitis and TNF-α/TNFR2 signal pathway in interleukin-10 deficient mice

(2008) Xiaowei Wei et al.   CLINICAL IMMUNOLOGY