Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics
出版年份 2014 全文链接
标题
Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics
作者
关键词
drug transporters, LC-MS/MS, membrane proteins, MRM proteomics, quantitative proteomics
出版物
AAPS Journal
Volume 16, Issue 4, Pages 634-648
出版商
American Association of Pharmaceutical Scientists (AAPS)
发表日期
2014-04-21
DOI
10.1208/s12248-014-9602-y
参考文献
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- (2014) Andreas Noack et al. PLoS One
- Mass Spectrometry-Based Targeted Proteomics as a Tool to Elucidate the Expression and Function of Intestinal Drug Transporters
- (2013) Stefan Oswald et al. AAPS Journal
- Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatin
- (2013) Yi-an Bi et al. BIOPHARMACEUTICS & DRUG DISPOSITION
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- LC–MS/MS-based quantification of clinically relevant intestinal uptake and efflux transporter proteins
- (2013) C. Gröer et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Absolute measurement of species differences in sodium taurocholate cotransporting polypeptide (NTCP/Ntcp) and its modulation in cultured hepatocytes
- (2013) Xi Qiu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2013) Bhagwat Prasad et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2013) Matthew R. Russell et al. JOURNAL OF PROTEOME RESEARCH
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- (2013) Alessandro Tanca et al. PROTEOMICS
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- (2012) U. Bergmann et al. ANALYTICAL CHEMISTRY
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- Membrane proteomics by high performance liquid chromatography-tandem mass spectrometry: Analytical approaches and challenges
- (2012) Dajana Vuckovic et al. PROTEOMICS
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- (2011) Benjamin C Orsburn et al. Expert Review of Proteomics
- Quantitative subproteomic analysis of age-related changes in mouse liver peroxisomes by iTRAQ LC–MS/MS
- (2011) Hanna Amelina et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
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- Quantitative Targeted Absolute Proteomics-Based Adme Research as A New Path to Drug Discovery and Development: Methodology, Advantages, Strategy, and Prospects
- (2011) Sumio Ohtsuki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- RIBAR and xRIBAR: Methods for Reproducible Relative MS/MS-based Label-Free Protein Quantification
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- Abundance of tegument surface proteins in the human blood fluke Schistosoma mansoni determined by QconCAT proteomics
- (2011) William Castro-Borges et al. Journal of Proteomics
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- (2011) Julia Maria Burkhart et al. Journal of Proteomics
- Development of a Protein Standard Absolute Quantification (PSAQ™) assay for the quantification of Staphylococcus aureus enterotoxin A in serum
- (2011) Annie Adrait et al. Journal of Proteomics
- Liquid chromatography/tandem mass spectrometry based targeted proteomics quantification of P-glycoprotein in various biological samples
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- (2010) Carla Schmidt et al. ANALYTICAL CHEMISTRY
- Regional P-Glycoprotein Activity and Inhibition at the Human Blood–Brain Barrier as Imaged by Positron Emission Tomography
- (2010) S Eyal et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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- (2010) Na Li et al. MOLECULAR PHARMACEUTICS
- Membrane transporters in drug development
- (2010) NATURE REVIEWS DRUG DISCOVERY
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- (2010) Annelies Vertommen et al. PLANTA
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- (2009) Jana Krenkova et al. ANALYTICAL CHEMISTRY
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- The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry
- (2009) Andrew N. Hoofnagle et al. JOURNAL OF IMMUNOLOGICAL METHODS
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- (2009) S. Eyal et al. JOURNAL OF NUCLEAR MEDICINE
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- (2009) M. Muzi et al. JOURNAL OF NUCLEAR MEDICINE
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