Good Riddance? Breaking Disease Susceptibility in the Era of New Breeding Technologies

Xanthomonas TAL effectors hijack host basal transcription factor IIA α and γ subunits for invasion

(2018) Ling Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A barley powdery mildew fungus non-autonomous retrotransposon encodes a peptide that supports penetration success on barley

(2018) Mathias Nottensteiner et al.   JOURNAL OF EXPERIMENTAL BOTANY

Solanaceous exocyst subunits are involved in immunity to diverse plant pathogens

(2018) Yu Du et al.   JOURNAL OF EXPERIMENTAL BOTANY

When resistance gene pyramids are not durable-the role of pathogen diversity

(2018) Remco Stam et al.   MOLECULAR PLANT PATHOLOGY

Why did filamentous plant pathogens evolve the potential to secrete hundreds of effectors to enable disease?

(2018) Hans Thordal-Christensen et al.   MOLECULAR PLANT PATHOLOGY

Functional characterization of the citrus canker susceptibility gene CsLOB1

(2018) Shuo Duan et al.   MOLECULAR PLANT PATHOLOGY

Arabidopsis HIPP27 is a host susceptibility gene for the beet cyst nematode Heterodera schachtii

(2018) Zoran S. Radakovic et al.   MOLECULAR PLANT PATHOLOGY

The β-Ketoacyl-CoA Synthase HvKCS1, Encoded by Cer-zh, Plays a Key Role in Synthesis of Barley Leaf Wax and Germination of Barley Powdery Mildew

(2018) Chao Li et al.   PLANT AND CELL PHYSIOLOGY

Novel alleles of rice eIF4G generated by CRISPR/Cas9-targeted mutagenesis confer resistance to Rice tungro spherical virus

(2018) Anca Macovei et al.   PLANT BIOTECHNOLOGY JOURNAL

Defended to the Nines: 25 Years of Resistance Gene Cloning Identifies Nine Mechanisms for R Protein Function

(2018) Jiorgos Kourelis et al.   PLANT CELL

Evaluating the importance of the tan spot ToxA-Tsn1 interaction in Australian wheat varieties

(2018) P. T. See et al.   PLANT PATHOLOGY

Potato MAP3K StVIK is required for Phytophthora infestans RXLR Effector Pi17316 to promote disease

(2018) Fraser Murphy et al.   PLANT PHYSIOLOGY

Tricked or trapped—Two decoy mechanisms in host–pathogen interactions

(2018) Judith K. Paulus et al.   PLoS Pathogens

Barley susceptibility factor RACB modulates transcript levels of signalling protein genes in compatible interaction with Blumeria graminis f.sp. hordei

(2017) Vera Schnepf et al.   MOLECULAR PLANT PATHOLOGY

mlo-Based Resistance: An Apparently Universal “Weapon” to Defeat Powdery Mildew Disease

(2017) Stefan Kusch et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Engineering canker-resistant plants through CRISPR/Cas9-targeted editing of the susceptibility gene CsLOB1 promoter in citrus

(2017) Aihong Peng et al.   PLANT BIOTECHNOLOGY JOURNAL

Pathogen-inducible Ta -Lr34res expression in heterologous barley confers disease resistance without negative pleiotropic effects

(2017) Rainer Boni et al.   PLANT BIOTECHNOLOGY JOURNAL

Genome editing of the disease susceptibility gene CsLOB1 in citrus confers resistance to citrus canker

(2017) Hongge Jia et al.   PLANT BIOTECHNOLOGY JOURNAL

GENERAL CONTROL NONREPRESSIBLE4 Degrades 14-3-3 and the RIN4 Complex to Regulate Stomatal Aperture with Implications on Nonhost Disease Resistance and Drought Tolerance

(2017) Amita Kaundal et al.   PLANT CELL

eIF4E Resistance: Natural Variation Should Guide Gene Editing

(2017) Anna Bastet et al.   TRENDS IN PLANT SCIENCE

Expression Profiling of Castanea Genes during Resistant and Susceptible Interactions with the Oomycete Pathogen Phytophthora cinnamomi Reveal Possible Mechanisms of Immunity

(2017) Carmen Santos et al.   Frontiers in Plant Science

Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion

(2017) Vladimir Nekrasov et al.   Scientific Reports

Comparative analysis of plant immune receptor architectures uncovers host proteins likely targeted by pathogens

(2016) Panagiotis F. Sarris et al.   BMC BIOLOGY

Of guards, decoys, baits and traps: pathogen perception in plants by type III effector sensors

(2016) Madiha Khan et al.   CURRENT OPINION IN MICROBIOLOGY

Barley disease susceptibility factor RACB acts in epidermal cell polarity and positioning of the nucleus

(2016) Björn Scheler et al.   JOURNAL OF EXPERIMENTAL BOTANY

A new eIF4E1 allele characterized by RNAseq data mining is associated with resistance to potato virus Y in tomato albeit with a low durability

(2016) Caroline Lebaron et al.   JOURNAL OF GENERAL VIROLOGY

Targeted promoter editing for rice resistance toXanthomonas oryzaepv.oryzaereveals differential activities forSWEET14-inducing TAL effectors

(2016) Servane Blanvillain-Baufumé et al.   PLANT BIOTECHNOLOGY JOURNAL

mlo-based powdery mildew resistance in hexaploid bread wheat generated by a non-transgenic TILLING approach

(2016) Johanna Acevedo-Garcia et al.   PLANT BIOTECHNOLOGY JOURNAL

A TILLING approach to generate broad-spectrum resistance to potyviruses in tomato is hampered byeIF4Egene redundancy

(2016) Camille Gauffier et al.   PLANT JOURNAL

The broadly effective recessive resistance genexa5of rice is a virulence effector-dependent quantitative trait for bacterial blight

(2016) Sheng Huang et al.   PLANT JOURNAL

Potato NPH3/RPT2-Like Protein StNRL1, Targeted by aPhytophthora infestansRXLR Effector, Is a Susceptibility Factor

(2016) Lina Yang et al.   PLANT PHYSIOLOGY

Using decoys to expand the recognition specificity of a plant disease resistance protein

(2016) S. H. Kim et al.   SCIENCE

Sequence diversification in recessive alleles of two host factor genes suggests adaptive selection for bymovirus resistance in cultivated barley from East Asia

(2016) Ping Yang et al.   THEORETICAL AND APPLIED GENETICS

Silencing of six susceptibility genes results in potato late blight resistance

(2016) Kaile Sun et al.   TRANSGENIC RESEARCH

New Insights into the Roles of Host Gene-Necrotrophic Effector Interactions in Governing Susceptibility of Durum Wheat to Tan Spot and Septoria nodorum Blotch

(2016) Simerjot K. Virdi et al.   G3-Genes Genomes Genetics

Tempered mlo broad-spectrum resistance to barley powdery mildew in an Ethiopian landrace

(2016) Xintian Ge et al.   Scientific Reports

Fungal Effectors and Plant Susceptibility

(2015) Libera Lo Presti et al.   Annual Review of Plant Biology

Co-option of developmentally regulated plant SWEET transporters for pathogen nutrition and abiotic stress tolerance

(2015) Divya Chandran   IUBMB LIFE

XA23 Is an Executor R Protein and Confers Broad-Spectrum Disease Resistance in Rice

(2015) Chunlian Wang et al.   Molecular Plant

A Host KH RNA-Binding Protein Is a Susceptibility Factor Targeted by an RXLR Effector to Promote Late Blight Disease

(2015) Xiaodan Wang et al.   Molecular Plant

Are we ready for back-to-nature crop breeding?

(2015) Michael G. Palmgren et al.   TRENDS IN PLANT SCIENCE

Plant Translation Factors and Virus Resistance

(2015) Hélène Sanfaçon   Viruses-Basel

Structure Analysis Uncovers a Highly Diverse but Structurally Conserved Effector Family in Phytopathogenic Fungi

(2015) Karine de Guillen et al.   PLoS Pathogens

Structural basis of pathogen recognition by an integrated HMA domain in a plant NLR immune receptor

(2015) A Maqbool et al.   eLife

Susceptibility Genes 101: How to Be a Good Host

(2014) Chris C.N. van Schie et al.   Annual Review of Phytopathology

Convergent Targeting of a Common Host Protein-Network by Pathogen Effectors from Three Kingdoms of Life

(2014) Ralf Weßling et al.   Cell Host & Microbe

CYP83A1 is required for metabolic compatibility of Arabidopsis with the adapted powdery mildew fungusErysiphe cruciferarum

(2014) Corina Weis et al.   NEW PHYTOLOGIST

TAL effectors - pathogen strategies and plant resistance engineering

(2014) Jens Boch et al.   NEW PHYTOLOGIST

The Rice TAL Effector-Dependent Resistance Protein XA10 Triggers Cell Death and Calcium Depletion in the Endoplasmic Reticulum

(2014) D. Tian et al.   PLANT CELL

Evolutionary Conserved Function of Barley and Arabidopsis 3-KETOACYL-CoA SYNTHASES in Providing Wax Signals for Germination of Powdery Mildew Fungi

(2014) D. Weidenbach et al.   PLANT PHYSIOLOGY

PROTEIN DISULFIDE ISOMERASE LIKE 5-1is a susceptibility factor to plant viruses

(2014) Ping Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic loss of susceptibility: a costly route to disease resistance?

(2013) R. Hückelhoven et al.   PLANT PATHOLOGY

Pivoting the Plant Immune System from Dissection to Deployment

(2013) J. L. Dangl et al.   SCIENCE

Susceptibility to plant disease: more than a failure of host immunity

(2013) Dmitry Lapin et al.   TRENDS IN PLANT SCIENCE

Quantitative Interactor Screening with next-generation Sequencing (QIS-Seq) identifies Arabidopsis thaliana MLO2 as a target of the Pseudomonas syringae type III effector HopZ2

(2012) Jennifer D Lewis et al.   BMC GENOMICS

A Common Signaling Process that Promotes Mycorrhizal and Oomycete Colonization of Plants

(2012) Ertao Wang et al.   CURRENT BIOLOGY

Appressorium morphogenesis and cell cycle progression are linked in the grass powdery mildew fungus Blumeria graminis

(2012) Anton Hansjakob et al.   Fungal Biology

Deployment of new biotechnologies in plant breeding

(2012) Maria Lusser et al.   NATURE BIOTECHNOLOGY

Loss of Abaxial Leaf Epicuticular Wax in Medicago truncatula irg1/palm1 Mutants Results in Reduced Spore Differentiation of Anthracnose and Nonhost Rust Pathogens

(2012) S. R. Uppalapati et al.   PLANT CELL

Durable broad-spectrum powdery mildew resistance in pea er1 plants is conferred by natural loss-of-function mutations in PsMLO1

(2011) MATT HUMPHRY et al.   MOLECULAR PLANT PATHOLOGY

A Barley ROP GTPase ACTIVATING PROTEIN Associates with Microtubules and Regulates Entry of the Barley Powdery Mildew Fungus into Leaf Epidermal Cells

(2011) Caroline Hoefle et al.   PLANT CELL

An Arabidopsis (malectin-like) leucine-rich repeat receptor-like kinase contributes to downy mildew disease

(2011) SOPHIE HOK et al.   PLANT CELL AND ENVIRONMENT

Independently Evolved Virulence Effectors Converge onto Hubs in a Plant Immune System Network

(2011) M. S. Mukhtar et al.   SCIENCE

BAXINHIBITOR-1Is Required for Full Susceptibility of Barley to Powdery Mildew

(2010) Ruth Eichmann et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Intracellular expression of a host-selective toxin, ToxA, in diverse plants phenocopies silencing of a ToxA-interacting protein, ToxABP1

(2010) Viola A. Manning et al.   NEW PHYTOLOGIST

Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1

(2010) J. I. B. Bos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A unique wheat disease resistance-like gene governs effector-triggered susceptibility to necrotrophic pathogens

(2010) J. D. Faris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Renaissance of Elicitors: Perception of Microbe-Associated Molecular Patterns and Danger Signals by Pattern-Recognition Receptors

(2009) Thomas Boller et al.   Annual Review of Plant Biology

Loss of susceptibility as a novel breeding strategy for durable and broad-spectrum resistance

(2009) Stefano Pavan et al.   MOLECULAR BREEDING

Tryptophan-Derived Metabolites Are Required for Antifungal Defense in the Arabidopsis mlo2 Mutant

(2009) C. Consonni et al.   PLANT PHYSIOLOGY

Recognition of AvrBs3-Like Proteins Is Mediated by Specific Binding to Promoters of Matching Pepper Bs3 Alleles

(2009) P. Romer et al.   PLANT PHYSIOLOGY

Loss of Function of a Proline-Containing Protein Confers Durable Disease Resistance in Rice

(2009) S. Fukuoka et al.   SCIENCE

Barley RIC171 interacts with RACBin plantaand supports entry of the powdery mildew fungus

(2008) Holger Schultheiss et al.   CELLULAR MICROBIOLOGY