标题
A minimal RNA ligand for potent RIG-I activation in living mice
作者
关键词
-
出版物
Science Advances
Volume 4, Issue 2, Pages e1701854
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2018-02-22
DOI
10.1126/sciadv.1701854
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response
- (2017) Peter Probst et al. VACCINE
- RIG-I inhibits the MAPK-dependent proliferation of BRAF mutant melanoma cells via MKP-1
- (2016) Attila Szabo et al. CELLULAR SIGNALLING
- Cutting Edge: The RIG-I Ligand 3pRNA Potently Improves CTL Cross-Priming and Facilitates Antiviral Vaccination
- (2016) Katharina Hochheiser et al. JOURNAL OF IMMUNOLOGY
- Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I
- (2016) Swapnil C. Devarkar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity
- (2016) Susanne Roth et al. Cell Reports
- Influenza Virus Adaptation PB2-627K Modulates Nucleocapsid Inhibition by the Pathogen Sensor RIG-I
- (2015) Michaela Weber et al. Cell Host & Microbe
- Connexins and pannexins in the immune system and lymphatic organs
- (2015) Aaron M. Glass et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Establishing the role of ATP for the function of the RIG-I innate immune sensor
- (2015) David C Rawling et al. eLife
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells
- (2014) P Duewell et al. CELL DEATH AND DIFFERENTIATION
- Therapeutic Activity of High-Dose Intratumoral IFN-β Requires Direct Effect on the Tumor Vasculature
- (2014) Robbert M. Spaapen et al. JOURNAL OF IMMUNOLOGY
- Activation of the RIG-I Pathway during Influenza Vaccination Enhances the Germinal Center Reaction, Promotes T Follicular Helper Cell Induction, and Provides a Dose-Sparing Effect and Protective Immunity
- (2014) R. R. Kulkarni et al. JOURNAL OF VIROLOGY
- Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
- (2014) Delphine Goubau et al. NATURE
- Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I
- (2014) Alys Peisley et al. NATURE
- Diverse intracellular pathogens activate type III interferon expression from peroxisomes
- (2014) Charlotte Odendall et al. NATURE IMMUNOLOGY
- The RIG-I ATPase core has evolved a functional requirement for allosteric stabilization by the Pincer domain
- (2014) David C. Rawling et al. NUCLEIC ACIDS RESEARCH
- RIG-I Self-Oligomerization Is Either Dispensable or Very Transient for Signal Transduction
- (2014) Jade Louber et al. PLoS One
- Parts, assembly and operation of the RIG-I family of motors
- (2013) David C Rawling et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon
- (2013) Jenish R Patel et al. EMBO REPORTS
- Defining the functional determinants for RNA surveillance by RIG-I
- (2013) Andrew Kohlway et al. EMBO REPORTS
- Turning Tumors into Vaccines: Co-opting the Innate Immune System
- (2013) Jasper G. van den Boorn et al. IMMUNITY
- RIG-I activation inhibits HIV replication in macrophages
- (2013) Yizhong Wang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent, Ubiquitin-Independent Manner
- (2013) Alys Peisley et al. MOLECULAR CELL
- Targeting the Cytosolic Innate Immune Receptors RIG-I and MDA5 Effectively Counteracts Cancer Cell Heterogeneity in Glioblastoma
- (2013) Martin Glas et al. STEM CELLS
- Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity
- (2013) Marie-Line Goulet et al. PLoS Pathogens
- Innate immune sensing of cancer: clues from an identified role for type I IFNs
- (2012) Thomas F. Gajewski et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response
- (2012) Xiaomo Jiang et al. IMMUNITY
- The Thermodynamic Basis for Viral RNA Detection by the RIG-I Innate Immune Sensor
- (2012) Adriana Vela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The 3′ Untranslated Regions of Influenza Genomic Sequences Are 5′PPP-Independent Ligands for RIG-I
- (2012) William G. Davis et al. PLoS One
- Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N7)-methyl transferase
- (2012) Y. Thillier et al. RNA
- A structure-based model of RIG-I activation
- (2012) D. Kolakofsky et al. RNA
- Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I
- (2012) Dahai Luo et al. STRUCTURE
- Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA
- (2011) Eva Kowalinski et al. CELL
- Structural Insights into RNA Recognition by RIG-I
- (2011) Dahai Luo et al. CELL
- Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells
- (2011) Mercedes B. Fuertes et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structural basis of RNA recognition and activation by innate immune receptor RIG-I
- (2011) Fuguo Jiang et al. NATURE
- RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications
- (2011) Reneé C. Ireton et al. Viruses-Basel
- RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
- (2011) Hilario J Ramos et al. Current Opinion in Virology
- Interferon-stimulated genes and their antiviral effector functions
- (2011) John W Schoggins et al. Current Opinion in Virology
- Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity
- (2010) Wenwen Zeng et al. CELL
- Metabolic Shifts in Immunity and Inflammation
- (2010) D. J. Kominsky et al. JOURNAL OF IMMUNOLOGY
- Interferon-λ in HCV Infection and Therapy
- (2010) Nicole E. Pagliaccetti et al. Viruses-Basel
- Interferon Lambda as a Potential New Therapeutic for Hepatitis C
- (2009) Dennis M. Miller et al. Annals of the New York Academy of Sciences
- TopHat: discovering splice junctions with RNA-Seq
- (2009) Cole Trapnell et al. BIOINFORMATICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus
- (2009) Martin Schlee et al. IMMUNITY
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Calcium signaling in immune cells
- (2008) Monika Vig et al. NATURE IMMUNOLOGY
- 5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
- (2008) Hendrik Poeck et al. NATURE MEDICINE
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