Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity

Activation of an Immunoregulatory and Antiviral Gene Expression Program in Poly(I:C)-Transfected Human Neutrophils

(2014) N. Tamassia et al.   JOURNAL OF IMMUNOLOGY

IFN-λ inhibits HIV-1 integration and post-transcriptional events in vitro, but there is only limited in vivo repression of viral production

(2012) Ren-Rong Tian et al.   ANTIVIRAL RESEARCH

JAK's SOCS: A Mechanism of Inhibition

(2012) Akihiko Yoshimura et al.   IMMUNITY

Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response

(2012) Xiaomo Jiang et al.   IMMUNITY

Intranasal Treatment with Poly(I{middle dot}C) Protects Aged Mice from Lethal Respiratory Virus Infections

(2012) J. Zhao et al.   JOURNAL OF VIROLOGY

5'-Triphosphate-Short Interfering RNA: Potent Inhibition of Influenza A Virus Infection by Gene Silencing and RIG-I Activation

(2012) L. Lin et al.   JOURNAL OF VIROLOGY

A Sendai Virus-Derived RNA Agonist of RIG-I as a Virus Vaccine Adjuvant

(2012) L. Martínez-Gil et al.   JOURNAL OF VIROLOGY

IFITM3 restricts the morbidity and mortality associated with influenza

(2012) Aaron R. Everitt et al.   NATURE

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

The yin and yang of viruses and interferons

(2012) Ben X. Wang et al.   TRENDS IN IMMUNOLOGY

Protective Role of Toll-like Receptor 3-Induced Type I Interferon in Murine Coronavirus Infection of Macrophages

(2012) Liudmila Mazaleuskaya et al.   Viruses-Basel

Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA

(2011) Eva Kowalinski et al.   CELL

Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter

(2011) S Mehdi Belgnaoui et al.   CURRENT OPINION IN IMMUNOLOGY

Interferon lambdas: the next cytokine storm

(2011) C. Kelly et al.   GUT

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

(2011) Marina Caskey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparative Analysis of Poxvirus Orthologues of the Vaccinia Virus E3 Protein: Modulation of Protein Kinase R Activity, Cytokine Responses, and Virus Pathogenicity

(2011) C. Myskiw et al.   JOURNAL OF VIROLOGY

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

(2011) Fuguo Jiang et al.   NATURE

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic Entry

(2011) Eric M. Feeley et al.   PLoS Pathogens

IFN-α and IFN-λ differ in their antiproliferative effects and duration of JAK/STAT signaling activity

(2010) Stephen G. Maher et al.   CANCER BIOLOGY & THERAPY

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Recognition of viruses by cytoplasmic sensors

(2010) Courtney Wilkins et al.   CURRENT OPINION IN IMMUNOLOGY

New developments in the induction and antiviral effectors of type I interferon

(2010) Su-Yang Liu et al.   CURRENT OPINION IN IMMUNOLOGY

Tripartite-motif proteins and innate immune regulation

(2010) Finlay W McNab et al.   CURRENT OPINION IN IMMUNOLOGY

Activation of host pattern recognition receptors by viruses

(2010) Kiva Brennan et al.   CURRENT OPINION IN MICROBIOLOGY

The Chase for the RIG-I Ligand—Recent Advances

(2010) Martin Schlee et al.   MOLECULAR THERAPY

Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication

(2010) K. V. Chakravarthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

(2010) A. Baum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

(2010) N. Shembade et al.   SCIENCE

RIGorous Detection: Exposing Virus Through RNA Sensing

(2010) J. Rehwinkel et al.   SCIENCE

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication

(2010) Priya Ranjan et al.   Virology Journal

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7

(2009) Delphine Goubau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Nonself RNA Pattern: Tri-p to Panhandle

(2009) Takashi Fujita   IMMUNITY

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells

(2009) Stephen McCartney et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells

(2009) Anne S Dejean et al.   NATURE IMMUNOLOGY

Recognition of viral nucleic acids in innate immunity

(2009) Mitsutoshi Yoneyama et al.   REVIEWS IN MEDICAL VIROLOGY

Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate-Dependent Translocase on Double-Stranded RNA

(2009) S. Myong et al.   SCIENCE

Risk for Depression During Interferon-Alpha Treatment Is Affected by the Serotonin Transporter Polymorphism

(2008) Francis E. Lotrich et al.   BIOLOGICAL PSYCHIATRY

TLRs and innate immunity

(2008) B. A. Beutler   BLOOD

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

Interleukin-29 Functions Cooperatively with Interferon to Induce Antiviral Gene Expression and Inhibit Hepatitis C Virus Replication

(2008) Nicole E. Pagliaccetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting the Apoptotic Pathway with BCL-2 Inhibitors Sensitizes Primary Chronic Lymphocytic Leukemia Cells to Vesicular Stomatitis Virus-Induced Oncolysis

(2008) V. F. Tumilasci et al.   JOURNAL OF VIROLOGY

The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I

(2008) Sheng Cui et al.   MOLECULAR CELL

How interferon-γ keeps autoimmune diseases in check

(2008) Hilde Kelchtermans et al.   TRENDS IN IMMUNOLOGY

Antagonizing activity of vaccinia virus E3L against human interferons in Huh7 cells

(2008) Janilyn Arsenio et al.   VIROLOGY

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

(2008) Markus Mordstein et al.   PLoS Pathogens

The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22

(2008) Stephen D. Barr et al.   PLoS Pathogens