标题
Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
作者
关键词
-
出版物
Frontiers in Endocrinology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-04-18
DOI
10.3389/fendo.2018.00177
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- mTORC1 Signaling: A Double-Edged Sword in Diabetic β Cells
- (2018) Amin Ardestani et al. Cell Metabolism
- Rare missense mutations in RECQL and POLG associate with inherited predisposition to breast cancer
- (2018) Anna Tervasmäki et al. INTERNATIONAL JOURNAL OF CANCER
- DNA polymerases in the mitochondria A critical review of the evidence
- (2017) William C Copeland Frontiers in Bioscience-Landmark
- Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
- (2017) Iosifina P. Foskolou et al. MOLECULAR CELL
- Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC
- (2017) Kiyotoshi Satoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways
- (2017) Thuc M. Le et al. Nature Communications
- A Critical Balance: dNTPs and the Maintenance of Genome Stability
- (2017) Chen‐Chun Pai et al. Genes
- Pancreatic Cancer Chemoresistance to Gemcitabine
- (2017) Manoj Amrutkar et al. Cancers
- Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer
- (2017) Erika S. Dahl et al. Frontiers in Oncology
- Targeted metabolome profiling by dual-probe microdialysis sampling and treatment using Gardenia jasminoides for rats with type 2 diabetes
- (2017) Lu Wang et al. Scientific Reports
- Alterations of Mitochondrial Function and Insulin Sensitivity in Human Obesity and Diabetes Mellitus
- (2016) Chrysi Koliaki et al. Annual Review of Nutrition
- Discoveries, metabolic roles and diseases of mitochondrial carriers: A review
- (2016) Ferdinando Palmieri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism
- (2016) Joni Nikkanen et al. Cell Metabolism
- Glucose-6-Phosphate Dehydrogenase Deficiency Improves Insulin Resistance With Reduced Adipose Tissue Inflammation in Obesity
- (2016) Mira Ham et al. DIABETES
- Commentary: Mitochondrial DNA damage and loss in diabetes
- (2016) Robert Gilkerson DIABETES-METABOLISM RESEARCH AND REVIEWS
- ATM kinase: Much more than a DNA damage responsive protein
- (2016) Ayushi Guleria et al. DNA REPAIR
- Regulation of uric acid metabolism and excretion
- (2016) Jessica Maiuolo et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Glucose-6-phosphate dehydrogenase deficiency and risk of colorectal cancer in Northern Sardinia
- (2016) Maria P. Dore et al. MEDICINE
- Targeting RRM2 and Mutant BRAF Is a Novel Combinatorial Strategy for Melanoma
- (2016) N. Fatkhutdinov et al. MOLECULAR CANCER RESEARCH
- ATM Mutations in Cancer: Therapeutic Implications
- (2016) M. Choi et al. MOLECULAR CANCER THERAPEUTICS
- Obesity is an independent risk factor for non-alcoholic fatty liver disease: evidence from a meta-analysis of 21 cohort studies
- (2016) L. Li et al. Obesity Reviews
- mTORC1 and mTORC2 in cancer and the tumor microenvironment
- (2016) L C Kim et al. ONCOGENE
- mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle
- (2016) I. Ben-Sahra et al. SCIENCE
- Mitochondrial dysfunction remodels one-carbon metabolism in human cells
- (2016) Xiaoyan Robert Bao et al. eLife
- Hyperuricemia-Related Diseases and Xanthine Oxidoreductase (XOR) Inhibitors: An Overview
- (2016) Changyi Chen et al. MEDICAL SCIENCE MONITOR
- Landscape of Phosphatidylinositol-3-Kinase Pathway Alterations Across 19 784 Diverse Solid Tumors
- (2016) Sherri Z. Millis et al. JAMA Oncology
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- Mitochondrial DNA Polymerase γ Mutations and Their Implications in mtDNA Alterations in Colorectal Cancer
- (2015) Katarzyna Linkowska et al. ANNALS OF HUMAN GENETICS
- Nucleotide metabolism, oncogene-induced senescence and cancer
- (2015) Katherine M. Aird et al. CANCER LETTERS
- Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications
- (2015) Rebecca Kohnken et al. Molecular Cancer
- Regulation of mammalian nucleotide metabolism and biosynthesis
- (2015) Andrew N. Lane et al. NUCLEIC ACIDS RESEARCH
- Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality
- (2015) Emily Jane Gallagher et al. PHYSIOLOGICAL REVIEWS
- Orotic Acid Induces Hypertension Associated with Impaired Endothelial Nitric Oxide Synthesis
- (2015) You-Jin Choi et al. TOXICOLOGICAL SCIENCES
- Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny
- (2015) W Lee et al. Cell Death & Disease
- Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities
- (2015) Madhusudhan Kollareddy et al. Nature Communications
- Uric Acid Produces an Inflammatory Response through Activation of NF-κB in the Hypothalamus: Implications for the Pathogenesis of Metabolic Disorders
- (2015) Wenjie Lu et al. Scientific Reports
- ATM Couples Replication Stress and Metabolic Reprogramming during Cellular Senescence
- (2015) Katherine M. Aird et al. Cell Reports
- Xanthine oxidoreductase in cancer: more than a differentiation marker
- (2015) Maria Giulia Battelli et al. Cancer Medicine
- Livers with Constitutive mTORC1 Activity Resist Steatosis Independent of Feedback Suppression of Akt
- (2015) Heidi L. Kenerson et al. PLoS One
- Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties
- (2015) Bhupendra Singh et al. PLoS One
- Gene Expression Levels as Predictive Markers of Outcome in Pancreatic Cancer after Gemcitabine-Based Adjuvant Chemotherapy
- (2015) Hayato Fujita et al. NEOPLASIA
- The MAPK pathway across different malignancies: A new perspective
- (2014) Mauricio Burotto et al. CANCER
- DNA Damage Response and Metabolic Disease
- (2014) Ippei Shimizu et al. Cell Metabolism
- Gemcitabine: Metabolism and molecular mechanisms of action, sensitivity and chemoresistance in pancreatic cancer
- (2014) Lucas de Sousa Cavalcante et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- GermlineTP53Mutations and the Changing Landscape of Li-Fraumeni Syndrome
- (2014) Junne Kamihara et al. HUMAN MUTATION
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- Regulation of the pentose phosphate pathway in cancer
- (2014) Peng Jiang et al. Protein & Cell
- Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes
- (2014) Richard Mackenzie et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Tumor suppressor p53 and its gain-of-function mutants in cancer
- (2013) J. Liu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Physiological and pathological roles of mitochondrial SLC25 carriers: Figure 1
- (2013) Manuel Gutiérrez-Aguilar et al. BIOCHEMICAL JOURNAL
- Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer
- (2013) Katherine M Aird et al. CELL CYCLE
- mTOR in aging, metabolism, and cancer
- (2013) Marion Cornu et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Uric Acid Secretion from Adipose Tissue and Its Increase in Obesity
- (2013) Yu Tsushima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Disruption of uridine homeostasis links liver pyrimidine metabolism to lipid accumulation
- (2013) Thuc T. Le et al. JOURNAL OF LIPID RESEARCH
- The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29
- (2013) James D. Young et al. MOLECULAR ASPECTS OF MEDICINE
- The mitochondrial ADP/ATP carrier (SLC25 family): Pathological implications of its dysfunction
- (2013) Benjamin Clémençon et al. MOLECULAR ASPECTS OF MEDICINE
- Causes and consequences of replication stress
- (2013) Michelle K. Zeman et al. NATURE CELL BIOLOGY
- Increased Oxidative Metabolism in the Li–Fraumeni Syndrome
- (2013) Ping-Yuan Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Thymidine Kinase 2 Deficiency-Induced mtDNA Depletion in Mouse Liver Leads to Defect β-Oxidation
- (2013) Xiaoshan Zhou et al. PLoS One
- Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1
- (2013) I. Ben-Sahra et al. SCIENCE
- Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence
- (2013) Katherine M. Aird et al. Cell Reports
- Next-generation sequencing reveals DGUOK mutations in adult patients with mitochondrial DNA multiple deletions
- (2012) D. Ronchi et al. BRAIN
- Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair
- (2012) Vincenzo D'Angiolella et al. CELL
- MYC on the Path to Cancer
- (2012) Chi V. Dang CELL
- p53-Induced Adipose Tissue Inflammation Is Critically Involved in the Development of Insulin Resistance in Heart Failure
- (2012) Ippei Shimizu et al. Cell Metabolism
- Mitochondrial Control of Cellular Life, Stress, and Death
- (2012) Lorenzo Galluzzi et al. CIRCULATION RESEARCH
- c-Myc and Cancer Metabolism
- (2012) D. M. Miller et al. CLINICAL CANCER RESEARCH
- Correlated Tissue Expression of Genes of Cytoplasmic and Mitochondrial Nucleotide Metabolisms in Normal Tissues is Disrupted in Transformed Tissues
- (2012) Vishal V. Gandhi et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells
- (2012) G. Pontarin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer metabolism: current perspectives and future directions
- (2012) C Muñoz-Pinedo et al. Cell Death & Disease
- ATM and the Molecular Pathogenesis of Ataxia Telangiectasia
- (2011) Peter J. McKinnon Annual Review of Pathology-Mechanisms of Disease
- Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
- (2011) Assaf C. Bester et al. CELL
- DNA building blocks: keeping control of manufacture
- (2011) Anders Hofer et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- G6PD Up-Regulation Promotes Pancreatic β-Cell Dysfunction
- (2011) Joo-Won Lee et al. ENDOCRINOLOGY
- Obesity, inflammation, and liver cancer
- (2011) Beicheng Sun et al. JOURNAL OF HEPATOLOGY
- p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
- (2011) Peng Jiang et al. NATURE CELL BIOLOGY
- Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization
- (2011) James Wesley Fairman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Diabetes mellitus and glucose-6-phosphate dehydrogenase deficiency: From one crisis to another
- (2010) C. Carette et al. DIABETES & METABOLISM
- Oxidative stress, inflammation, and cancer: How are they linked?
- (2010) Simone Reuter et al. FREE RADICAL BIOLOGY AND MEDICINE
- Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
- (2010) Marianne Berg et al. Molecular Cancer
- Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells
- (2010) C Favre et al. ONCOGENE
- The molecular determinants of de novo nucleotide biosynthesis in cancer cells
- (2009) Xuemei Tong et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Ultraviolet and tandem mass spectrometry for simultaneous quantification of 21 pivotal metabolites in plasma from patients with diabetic nephropathy
- (2009) Jian-Fei Xia et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Mutations in mitochondrial DNA polymerase-γ promote breast tumorigenesis
- (2009) Keshav K Singh et al. JOURNAL OF HUMAN GENETICS
- Inborn errors of purine and pyrimidine metabolism
- (2009) A. Jurecka JOURNAL OF INHERITED METABOLIC DISEASE
- The H Syndrome Is Caused by Mutations in the Nucleoside Transporter hENT3
- (2008) Vered Molho-Pessach et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Broad Overexpression of Ribonucleotide Reductase Genes in Mice Specifically Induces Lung Neoplasms
- (2008) X. Xu et al. CANCER RESEARCH
- Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice
- (2008) Yasuhiro Izumiya et al. Cell Metabolism
- Mitochondrial DNA depletion syndrome due to mutations in the RRM2B gene
- (2008) Belén Bornstein et al. NEUROMUSCULAR DISORDERS
- Uric Acid: The Oxidant-Antioxidant Paradox
- (2008) Yuri Y. Sautin et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Global Regulation of Nucleotide Biosynthetic Genes by c-Myc
- (2008) Yen-Chun Liu et al. PLoS One
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inherited Mitochondrial Diseases of DNA Replication
- (2007) William C. Copeland Annual Review of Medicine
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now