标题
A Critical Balance: dNTPs and the Maintenance of Genome Stability
作者
关键词
-
出版物
Genes
Volume 8, Issue 2, Pages 57
出版商
MDPI AG
发表日期
2017-01-31
DOI
10.3390/genes8020057
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism
- (2016) Joni Nikkanen et al. Cell Metabolism
- DNA replication origins—where do we begin?
- (2016) Marie-Noëlle Prioleau et al. GENES & DEVELOPMENT
- A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation
- (2016) Simon Gemble et al. JOURNAL OF CELL SCIENCE
- Who Is Leading the Replication Fork, Pol ε or Pol δ?
- (2016) Peter M.J. Burgers et al. MOLECULAR CELL
- Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome
- (2016) Catarina P. Samora et al. MOLECULAR CELL
- Processing ribonucleotides incorporated during eukaryotic DNA replication
- (2016) Jessica S. Williams et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Resolving individual steps of Okazaki-fragment maturation at a millisecond timescale
- (2016) Joseph L Stodola et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mitochondrial purine and pyrimidine metabolism and beyond
- (2016) Liya Wang NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Heterozygous colon cancer-associated mutations ofSAMHD1have functional significance
- (2016) Matilda Rentoft et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Resolving individual steps of Okazaki-fragment maturation at a millisecond timescale
- (2016) Joseph L Stodola et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells
- (2016) Chih-Wei Chen et al. Cell Reports
- Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage
- (2016) Hervé Técher et al. Cell Reports
- Error-free and mutagenic processing of topoisomerase 1-provoked damage at genomic ribonucleotides
- (2015) J. L. Sparks et al. EMBO JOURNAL
- Nucleotide Salvage Deficiencies, DNA Damage and Neurodegeneration
- (2015) Michael Fasullo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
- (2015) Ralph Zellweger et al. JOURNAL OF CELL BIOLOGY
- Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications
- (2015) Rebecca Kohnken et al. Molecular Cancer
- A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands
- (2015) Robert E. Johnson et al. MOLECULAR CELL
- Fatty acid carbon is essential for dNTP synthesis in endothelial cells
- (2015) Sandra Schoors et al. NATURE
- Regulated eukaryotic DNA replication origin firing with purified proteins
- (2015) Joseph T. P. Yeeles et al. NATURE
- Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway
- (2015) Federica Calì et al. NUCLEIC ACIDS RESEARCH
- Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools
- (2015) Danielle L. Watt et al. NUCLEIC ACIDS RESEARCH
- Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity
- (2015) Tony M. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants
- (2015) Lindsey N. Williams et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nucleotide Pool Depletion Induces G-Quadruplex-Dependent Perturbation of Gene Expression
- (2015) Charikleia Papadopoulou et al. Cell Reports
- Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA
- (2015) Simon Gemble et al. PLoS Genetics
- The programme of DNA replication: beyond genome duplication
- (2015) Blanca Gómez-Escoda et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells
- (2014) Cristina E. Requena et al. BIOCHEMICAL JOURNAL
- DNA Replication and Oncogene-Induced Replicative Stress
- (2014) Stephanie A. Hills et al. CURRENT BIOLOGY
- Deoxyribonucleotides as genetic and metabolic regulators
- (2014) Christopher K. Mathews FASEB JOURNAL
- Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies
- (2014) Y Aye et al. ONCOGENE
- DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin
- (2014) M. K. Ayrapetov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The causes of replication stress and their consequences on genome stability and cell fate
- (2014) Indiana Magdalou et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Cellular regulation of ribonucleotide reductase in eukaryotes
- (2014) Estrella Guarino et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Molecular Mechanisms of DNA Replication Checkpoint Activation
- (2014) Bénédicte Recolin et al. Genes
- Hypothesis: Local dNTP depletion as the cause of microsatellite repeat instability during replication (Comment on DOI 10.1002/bies.201200128)
- (2013) Michael Leffak BIOESSAYS
- Inhibition of DNA synthesis facilitates expansion of low-complexity repeats
- (2013) Andrei Kuzminov BIOESSAYS
- Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools
- (2013) A. Gupta et al. GENETICS
- Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutières Syndrome and HIV-1 Restriction
- (2013) Natalia Beloglazova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated
- (2013) O. Fleck et al. JOURNAL OF CELL SCIENCE
- Controlling DNA replication origins in response to DNA damage - inhibit globally, activate locally
- (2013) M. Yekezare et al. JOURNAL OF CELL SCIENCE
- Pif1 family helicases suppress genome instability at G-quadruplex motifs
- (2013) Katrin Paeschke et al. NATURE
- Maintaining genome stability in the nervous system
- (2013) Peter J McKinnon NATURE NEUROSCIENCE
- Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes
- (2013) B. Stillman PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypermutability and error catastrophe due to defects in ribonucleotide reductase
- (2013) D. Ahluwalia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cost of rNTP/dNTP pool imbalance at the replication fork
- (2013) N. Y. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells
- (2013) E. Franzolin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA Replication Timing
- (2013) N. Rhind et al. Cold Spring Harbor Perspectives in Biology
- Rescuing Stalled or Damaged Replication Forks
- (2013) J. T. P. Yeeles et al. Cold Spring Harbor Perspectives in Biology
- Regulating DNA Replication in Eukarya
- (2013) K. Siddiqui et al. Cold Spring Harbor Perspectives in Biology
- Tumor Cells Require Thymidylate Kinase to Prevent dUTP Incorporation during DNA Repair
- (2012) Chun-Mei Hu et al. CANCER CELL
- Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
- (2012) Martin A.M. Reijns et al. CELL
- Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair
- (2012) Vincenzo D'Angiolella et al. CELL
- Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ
- (2012) Jessica S. Williams et al. DNA REPAIR
- Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ
- (2012) Anders R. Clausen et al. DNA REPAIR
- Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype
- (2012) Marta B Davidson et al. EMBO JOURNAL
- dNTP pools determine fork progression and origin usage under replication stress
- (2012) Jérôme Poli et al. EMBO JOURNAL
- A Mammalian-Like DNA Damage Response of Fission Yeast to Nucleoside Analogs
- (2012) S. A. Sabatinos et al. GENETICS
- RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA
- (2012) Federico Lazzaro et al. MOLECULAR CELL
- Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
- (2012) Claire Palles et al. NATURE GENETICS
- Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit Expression
- (2012) Joshua C. Saldivar et al. PLoS Genetics
- Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
- (2011) Assaf C. Bester et al. CELL
- DNA building blocks: keeping control of manufacture
- (2011) Anders Hofer et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
- (2011) David C. Goldstone et al. NATURE
- SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
- (2011) Nadine Laguette et al. NATURE
- Hydroxyurea induces de novo copy number variants in human cells
- (2011) M. F. Arlt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coli
- (2011) S. Gon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I
- (2011) N. Kim et al. SCIENCE
- DNA replication: Failures and inverted fusions
- (2011) Antony M. Carr et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome
- (2011) Pauline Chabosseau et al. Nature Communications
- Limited dCTP Availability Accounts for Mitochondrial DNA Depletion in Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)
- (2011) Emiliano González-Vioque et al. PLoS Genetics
- Replication stress, a source of epigenetic aberrations in cancer?
- (2010) Zuzana Jasencakova et al. BIOESSAYS
- Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells
- (2010) Hiroyuki Niida et al. CANCER SCIENCE
- ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks
- (2010) Niraj M. Shanbhag et al. CELL
- Break-induced ATR and Ddb1-Cul4Cdt2 ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast
- (2010) J. Moss et al. GENES & DEVELOPMENT
- Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase
- (2010) H. Niida et al. GENES & DEVELOPMENT
- Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair
- (2010) Eva Petermann et al. MOLECULAR CELL
- Genome instability due to ribonucleotide incorporation into DNA
- (2010) Stephanie A Nick McElhinny et al. Nature Chemical Biology
- Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint
- (2010) Dinesh Kumar et al. NUCLEIC ACIDS RESEARCH
- Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools
- (2010) D. Kumar et al. NUCLEIC ACIDS RESEARCH
- Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases
- (2010) S. A. Nick McElhinny et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Heterozygous Truncating Mutation in RRM2B Causes Autosomal-Dominant Progressive External Ophthalmoplegia with Multiple mtDNA Deletions
- (2009) Henna Tyynismaa et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mitochondrial Neurogastrointestinal Encephalopathy Due to Mutations in RRM2B
- (2009) Aziz Shaibani et al. ARCHIVES OF NEUROLOGY
- ATR/Mec1: coordinating fork stability and repair
- (2009) Anna M Friedel et al. CURRENT OPINION IN CELL BIOLOGY
- Mouse RS21-C6 is a mammalian 2′-deoxycytidine 5′-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine
- (2009) Mari Nonaka et al. FEBS Journal
- Implication of Checkpoint Kinase-dependent Up-regulation of Ribonucleotide Reductase R2 in DNA Damage Response
- (2009) Yong-Wei Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
- (2009) Gillian I Rice et al. NATURE GENETICS
- Mechanisms of change in gene copy number
- (2009) P. J. Hastings et al. NATURE REVIEWS GENETICS
- Epigenetic inheritance during the cell cycle
- (2009) Aline V. Probst et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
- (2009) Andrew J. Holland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA repair deficiency and neurological disease
- (2009) Peter J. McKinnon NATURE REVIEWS NEUROSCIENCE
- Broad Overexpression of Ribonucleotide Reductase Genes in Mice Specifically Induces Lung Neoplasms
- (2008) X. Xu et al. CANCER RESEARCH
- Identification of pathways controlling DNA damage induced mutation in Saccharomyces cerevisiae
- (2008) Ewa T. Lis et al. DNA REPAIR
- Genome instability: a mechanistic view of its causes and consequences
- (2008) Andrés Aguilera et al. NATURE REVIEWS GENETICS
- Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage
- (2008) Nasim Sabouri et al. NUCLEIC ACIDS RESEARCH
- DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation
- (2008) K. Hastak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage
- (2008) G. Pontarin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Oncogene-Induced DNA Damage Model for Cancer Development
- (2008) T. D. Halazonetis et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now