The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature
出版年份 2016 全文链接
标题
The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature
作者
关键词
-
出版物
Biomarkers in Medicine
Volume 10, Issue 1, Pages 19-34
出版商
Future Medicine Ltd
发表日期
2015-08-28
DOI
10.2217/bmm.14.105
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cerebrospinal Fluid α-Synuclein Does Not Discriminate Between Dementia Disorders
- (2017) Petra E. Spies et al. JOURNAL OF ALZHEIMERS DISEASE
- CSF α-Synuclein Does Not Discriminate Dementia with Lewy Bodies from Alzheimer's Disease
- (2017) Fransje E. Reesink et al. JOURNAL OF ALZHEIMERS DISEASE
- Interference from Heterophilic Antibodies in Amyloid-β Oligomer ELISAs
- (2017) Dag Sehlin et al. JOURNAL OF ALZHEIMERS DISEASE
- CSF Neurofilament Light Chain but not FLT3 Ligand Discriminates Parkinsonian Disorders
- (2015) Megan K. Herbert et al. Frontiers in Neurology
- Increased CSF α-synuclein levels in Alzheimer's disease: Correlation with tau levels
- (2014) Sylvie Slaets et al. Alzheimers & Dementia
- Detection of disease-associated α-synuclein in the cerebrospinal fluid: a feasibility study
- (2014) Ursula Unterberger et al. CLINICAL NEUROPATHOLOGY
- CSF α-synuclein and UCH-L1 levels in Parkinson's disease and atypical parkinsonian disorders
- (2014) Stefania Mondello et al. PARKINSONISM & RELATED DISORDERS
- Elevated levels of cerebrospinal fluid α-synuclein oligomers in healthy asymptomatic LRRK2 mutation carriers
- (2014) Jan O. Aasly et al. Frontiers in Aging Neuroscience
- Differential role of CSF alpha-synuclein species, tau, and Aβ42 in Parkinson's Disease
- (2014) Lucilla Parnetti et al. Frontiers in Aging Neuroscience
- CSF α-synuclein improves diagnostic and prognostic performance of CSF tau and Aβ in Alzheimer’s disease
- (2013) Jon B. Toledo et al. ACTA NEUROPATHOLOGICA
- Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein
- (2013) Dora Games et al. AMERICAN JOURNAL OF PATHOLOGY
- May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum α-Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease?
- (2013) Emilio Fernández et al. ANTIOXIDANTS & REDOX SIGNALING
- Heterophilic antibody interference in immunometric assays
- (2013) Nils Bolstad et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Reduced α-synuclein levels in cerebrospinal fluid in Parkinson's disease are unrelated to clinical and imaging measures of disease severity
- (2013) K. D. van Dijk et al. EUROPEAN JOURNAL OF NEUROLOGY
- Cerebrospinal fluid biomarkers in Parkinson disease
- (2013) Lucilla Parnetti et al. Nature Reviews Neurology
- Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort
- (2013) B. Mollenhauer et al. NEUROLOGY
- Low CSF Levels of Both α-Synuclein and the α-Synuclein Cleaving Enzyme Neurosin in Patients with Synucleinopathy
- (2013) Malin Wennström et al. PLoS One
- The Diagnostic Value of CSF α-Synuclein in the Differential Diagnosis of Dementia with Lewy Bodies vs. Normal Subjects and Patients with Alzheimer’s Disease
- (2013) Elisabeth Kapaki et al. PLoS One
- An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology
- (2012) Gabor G. Kovacs et al. ACTA NEUROPATHOLOGICA
- Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders
- (2012) Sara Hall et al. ARCHIVES OF NEUROLOGY
- Recommendations to standardize preanalytical confounding factors in Alzheimer’s and Parkinson’s disease cerebrospinal fluid biomarkers: an update
- (2012) Marta del Campo et al. Biomarkers in Medicine
- Novel One-step Immunoassays to Quantify α-Synuclein
- (2012) Michael Bidinosti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Elevated Levels of α-Synuclein Oligomer in the Cerebrospinal Fluid of Drug-Naïve Patients with Parkinson's Disease
- (2012) Min Jeong Park et al. Journal of Clinical Neurology
- α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system
- (2012) Brit Mollenhauer et al. JOURNAL OF NEURAL TRANSMISSION
- Cerebrospinal fluid α-synuclein levels are elevated in multiple sclerosis and neuromyelitis optica patients during replase
- (2012) Honghao Wang et al. JOURNAL OF NEUROCHEMISTRY
- Development of electrochemiluminescence-based singleplex and multiplex assays for the quantification of α-synuclein and other proteins in cerebrospinal fluid
- (2012) Niels Kruse et al. METHODS
- Naturally occurring -synuclein autoantibody levels are lower in patients with Parkinson disease
- (2012) D. Besong-Agbo et al. NEUROLOGY
- Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects
- (2012) Brit Mollenhauer et al. NEUROSCIENCE LETTERS
- α-Synuclein Levels in Blood Plasma from LRRK2 Mutation Carriers
- (2012) Ana Gorostidi et al. PLoS One
- Alpha-synuclein in the Cerebrospinal Fluid Differentiates Synucleinopathies (Parkinson Disease, Dementia With Lewy Bodies, Multiple System Atrophy) From Alzheimer Disease
- (2011) Fuyuki Tateno et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease
- (2011) Ivana Devic et al. BRAIN
- Decreased α-Synuclein Serum Levels in Patients with Lewy Body Dementia Compared to Alzheimer’s Disease Patients and Control Subjects
- (2011) Christoph Laske et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease
- (2011) Penelope G. Foulds et al. FASEB JOURNAL
- Enzyme-linked immunosorbent assays for alpha-synuclein with species and multimeric state specificities
- (2011) He-Jin Lee et al. JOURNAL OF NEUROSCIENCE METHODS
- α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
- (2011) Brit Mollenhauer et al. LANCET NEUROLOGY
- Cerebrospinal fluid Tau/α-synuclein ratio in Parkinson's disease and degenerative dementias
- (2011) Lucilla Parnetti et al. MOVEMENT DISORDERS
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function
- (2011) Min Shi et al. NEUROBIOLOGY OF AGING
- CSF α-synuclein does not differentiate between parkinsonian disorders
- (2011) M.B. Aerts et al. NEUROBIOLOGY OF AGING
- Detection of elevated levels of -synuclein oligomers in CSF from patients with Parkinson disease
- (2011) K. A. Bruggink et al. NEUROLOGY
- CSF α-synuclein concentrations do not fluctuate over hours and are not correlated to amyloid β in humans
- (2011) Petra E. Spies et al. NEUROSCIENCE LETTERS
- Assessment of α-Synuclein Secretion in Mouse and Human Brain Parenchyma
- (2011) Evangelia Emmanouilidou et al. PLoS One
- The Parkinson Progression Marker Initiative (PPMI)
- (2011) Kenneth Marek et al. PROGRESS IN NEUROBIOLOGY
- Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson’s disease
- (2010) Kelly Del Tredici et al. ACTA NEUROPATHOLOGICA
- Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
- (2010) Min Shi et al. ANNALS OF NEUROLOGY
- SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein Level
- (2010) Ignacio F. Mata et al. ARCHIVES OF NEUROLOGY
- Quantification of α-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies
- (2010) Brit Mollenhauer et al. Biomarkers in Medicine
- DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease
- (2010) Zhen Hong et al. BRAIN
- Differential levels of -synuclein, -amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease
- (2010) K. Kasuga et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Plasma α-synuclein in patients with Parkinson's disease with and without treatment
- (2010) Raquel Duran et al. MOVEMENT DISORDERS
- Detection of elevated levels of -synuclein oligomers in CSF from patients with Parkinson disease
- (2010) T. Tokuda et al. NEUROLOGY
- Detection of elevated levels of soluble -synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies
- (2009) K. E. Paleologou et al. BRAIN
- Amyloid- Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
- (2009) J.-E. Kang et al. SCIENCE
- CSF α-synuclein levels in dementia with Lewy bodies and Alzheimer's disease
- (2008) Moeko Noguchi-Shinohara et al. BRAIN RESEARCH
- Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration
- (2008) Brit Mollenhauer et al. EXPERIMENTAL NEUROLOGY
- Lymphomonocyte alpha-synuclein levels in aging and in Parkinson disease
- (2008) Laura Brighina et al. NEUROBIOLOGY OF AGING
- Red Blood Cells Are the Major Source of Alpha-Synuclein in Blood
- (2008) Robin Barbour et al. Neurodegenerative Diseases
- Cerebrospinal fluid α-synuclein in neurodegenerative disorders—A marker of synapse loss?
- (2008) Annika Öhrfelt et al. NEUROSCIENCE LETTERS
- GATA transcription factors directly regulate the Parkinson's disease-linked gene -synuclein
- (2008) C. R. Scherzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A more efficient enzyme-linked immunosorbent assay for measurement of α-synuclein in cerebrospinal fluid
- (2007) Wieneke J.A. van Geel et al. JOURNAL OF NEUROSCIENCE METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started