The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor
出版年份 2018 全文链接
标题
The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor
作者
关键词
-
出版物
Genes
Volume 9, Issue 2, Pages 105
出版商
MDPI AG
发表日期
2018-02-20
DOI
10.3390/genes9020105
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Rapid identification and validation of novel targeted approaches for Glioblastoma: A combined ex vivo-in vivo pharmaco-omic model
- (2018) Ahmad Daher et al. EXPERIMENTAL NEUROLOGY
- Sohlh1 suppresses glioblastoma cell proliferation, migration, and invasion by inhibition of Wnt/β-catenin signaling
- (2018) Xinyu Liu et al. MOLECULAR CARCINOGENESIS
- Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors
- (2017) Martina Ferri et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Epigenetically controlled Six3 expression regulates glioblastoma cell proliferation and invasion alongside modulating the activation levels of WNT pathway members
- (2017) Baoxin Zhang et al. JOURNAL OF NEURO-ONCOLOGY
- Aberrant Wnt signaling: a special focus in CNS diseases
- (2017) Mercedes Arnés et al. JOURNAL OF NEUROGENETICS
- Blocking MIR155HG/miR-155 axis inhibits mesenchymal transition in glioma
- (2017) Xuechao Wu et al. NEURO-ONCOLOGY
- Suppression of planar cell polarity signaling and migration in glioblastoma by Nrdp1-mediated Dvl polyubiquitination
- (2017) J H Wald et al. ONCOGENE
- Targeting WNT Signaling for Multifaceted Glioblastoma Therapy
- (2017) Matthew McCord et al. Frontiers in Cellular Neuroscience
- Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors
- (2017) Adriana Bajetto et al. Frontiers in Cellular Neuroscience
- Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma
- (2017) Takuya Furuta et al. Oncotarget
- Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways
- (2017) Vladimir N. Ivanov et al. Oncotarget
- RYK promotes the stemness of glioblastoma cells via the WNT/ β-catenin pathway
- (2017) Assunta Adamo et al. Oncotarget
- Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas
- (2017) et al. Genes
- PPAR-γ Agonists As Antineoplastic Agents in Cancers with Dysregulated IGF Axis
- (2017) Veronica Vella et al. Frontiers in Endocrinology
- Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway
- (2017) Chiara Cilibrasi et al. PLoS One
- MicroRNA-106a-5p facilitates human glioblastoma cell proliferation and invasion by targeting adenomatosis polyposis coli protein
- (2016) Dazhi Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Wnt inhibition is dysregulated in gliomas and its re-establishment inhibits proliferation and tumor sphere formation
- (2016) Kirsten Strømme Kierulf-Vieira et al. EXPERIMENTAL CELL RESEARCH
- Harnessing nanomedicine for therapeutic intervention in glioblastoma
- (2016) Anna Gutkin et al. Expert Opinion on Drug Delivery
- Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma
- (2016) C. Bastiancich et al. JOURNAL OF CONTROLLED RELEASE
- Clipping the Wings of Glioblastoma: Modulation of WNT as a Novel Therapeutic Strategy
- (2016) Abigail K. Suwala et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Expression patterns of Wnt signaling component, secreted frizzled-related protein 3 in astrocytoma and glioblastoma
- (2016) NIVES PEĆINA-ŠLAUS et al. Molecular Medicine Reports
- AKT/GSK3β Signaling in Glioblastoma
- (2016) Ewelina Majewska et al. NEUROCHEMICAL RESEARCH
- Perichondrium mesenchymal stem cells inhibit the growth of breast cancer cells via the DKK-1/Wnt/β-catenin signaling pathway
- (2016) Min Li et al. ONCOLOGY REPORTS
- Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?
- (2016) Jessica Roos et al. PHARMACOLOGY & THERAPEUTICS
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells
- (2016) Ignacio Sancho-Martinez et al. Nature Communications
- A 4-miRNA signature predicts the therapeutic outcome of glioblastoma
- (2016) Michel Mittelbronn et al. Oncotarget
- Effective treatment of glioblastoma requires crossing the blood–brain barrier and targeting tumors including cancer stem cells: The promise of nanomedicine
- (2015) Sang-Soo Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-603 promotes glioma cell growth via Wnt/β-catenin pathway by inhibiting WIF1 and CTNNBIP1
- (2015) Mian Guo et al. CANCER LETTERS
- Diverse Targets of -Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
- (2015) Y.-W. Chang et al. CANCER RESEARCH
- Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells
- (2015) C. Venugopal et al. CLINICAL CANCER RESEARCH
- Glioblastoma Multiforme Formation and EMT: Role of FoxM1 Transcription Factor
- (2015) Zhongyong Wang et al. CURRENT PHARMACEUTICAL DESIGN
- Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma
- (2015) Thibaut Fourniols et al. JOURNAL OF CONTROLLED RELEASE
- Evolution of the Karnosky Performance Status throughout life in glioblastoma patients
- (2015) Adama Sacko et al. JOURNAL OF NEURO-ONCOLOGY
- Sulforaphane enhances temozolomide-induced apoptosis because of down-regulation of miR-21 via Wnt/β-catenin signaling in glioblastoma
- (2015) FengMing Lan et al. JOURNAL OF NEUROCHEMISTRY
- Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells
- (2015) Ulf D. Kahlert et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- WNT signaling in glioblastoma and therapeutic opportunities
- (2015) Yeri Lee et al. LABORATORY INVESTIGATION
- miR-577 inhibits glioblastoma tumor growth via the Wnt signaling pathway
- (2015) Weiguang Zhang et al. MOLECULAR CARCINOGENESIS
- WIF1 re-expression in glioblastoma inhibits migration through attenuation of non-canonical WNT signaling by downregulating the lncRNA MALAT1
- (2015) I Vassallo et al. ONCOGENE
- Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway
- (2015) JUNJIE MIAO et al. ONCOLOGY REPORTS
- Secreted Frizzled-Related Protein 4 Inhibits Glioma Stem-Like Cells by Reversing Epithelial to Mesenchymal Transition, Inducing Apoptosis and Decreasing Cancer Stem Cell Properties
- (2015) Bhuvanalakshmi G et al. PLoS One
- MSX1 inhibits cell migration and invasion through regulating the Wnt/β-catenin pathway in glioblastoma
- (2015) Haiquan Tao et al. TUMOR BIOLOGY
- HOXA13 is a potential GBM diagnostic marker and promotes glioma invasion by activating the Wnt and TGF-β pathways
- (2015) Ran Duan et al. Oncotarget
- Involvement of Wnt/β-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma
- (2015) Weiwei Wang et al. Oncotarget
- LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program
- (2015) Xing-gang Mao et al. Oncotarget
- Oncolytic virotherapy for ALL: MSCs to the rescue
- (2014) E. M. Horwitz BLOOD
- The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells
- (2014) M R Moniri et al. CANCER GENE THERAPY
- Wnt signalling in neuronal differentiation and development
- (2014) Nibaldo C. Inestrosa et al. CELL AND TISSUE RESEARCH
- The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish
- (2014) T. Young et al. DEVELOPMENT
- The expression of Wnt-inhibitor DKK1 (Dickkopf 1) is determined by intercellular crosstalk and hypoxia in human malignant gliomas
- (2014) Ke-Tai Guo et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti–high mobility group box 1 activity: targeting of colon cancer
- (2014) Hiroto Kikuchi et al. JOURNAL OF SURGICAL RESEARCH
- Mesenchymal stem cells and cancer: Friends or enemies?
- (2014) In-Sun Hong et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
- (2014) Mark R. Gilbert et al. NEW ENGLAND JOURNAL OF MEDICINE
- New Considerations in Radiation Treatment Planning for Brain Tumors: Neural Progenitor Cell–Containing Niches
- (2014) Carmen Kut et al. SEMINARS IN RADIATION ONCOLOGY
- Isolation and in Vitro Characterization of Bovine Amniotic Fluid Derived Stem Cells at Different Trimesters of Pregnancy
- (2014) B. Rossi et al. Stem Cell Reviews and Reports
- Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways
- (2014) Sachin S. Rathod et al. FEBS Open Bio
- The role of the non-canonical Wnt–planar cell polarity pathway in neural crest migration
- (2013) Roberto Mayor et al. BIOCHEMICAL JOURNAL
- Immunoreactivity of Wnt5a, Fzd2, Fzd6, and Ryk in glioblastoma: evaluative methodology for DAB chromogenic immunostaining
- (2013) Hirofumi Hirano et al. Brain Tumor Pathology
- Identification and Characterization of a Small-Molecule Inhibitor of Wnt Signaling in Glioblastoma Cells
- (2013) A. De Robertis et al. MOLECULAR CANCER THERAPEUTICS
- Tumour heterogeneity and cancer cell plasticity
- (2013) Corbin E. Meacham et al. NATURE
- MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation
- (2013) Sabit Delic et al. NEURO-ONCOLOGY
- Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma
- (2013) Roshan Mahabir et al. NEURO-ONCOLOGY
- Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain
- (2013) Marta B. Wisniewska NEUROCHEMICAL RESEARCH
- Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling
- (2013) Iolanda D'Alimonte et al. Stem Cell Research
- Wnt Signaling Behaves as a “Master Regulator” in the Osteogenic and Adipogenic Commitment of Human Amniotic Fluid Mesenchymal Stem Cells
- (2013) Iolanda D’Alimonte et al. Stem Cell Reviews and Reports
- Embryonic stem cells neural differentiation qualifies the role of Wnt/β-Catenin signals in human telencephalic specification and regionalization
- (2013) Camille Nicoleau et al. STEM CELLS
- Therapeutic Efficacy and Fate of Bimodal Engineered Stem Cells in Malignant Brain Tumors
- (2013) Jordi Martinez-Quintanilla et al. STEM CELLS
- WNT signaling in neuronal maturation and synaptogenesis
- (2013) Silvana B. Rosso et al. Frontiers in Cellular Neuroscience
- An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma
- (2013) Esther Rheinbay et al. Cell Reports
- The importance of Wnt signalling for neurodegeneration in Parkinson's disease
- (2012) Daniel C. Berwick et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition
- (2012) Ulf D. Kahlert et al. CANCER LETTERS
- FoxM1 and Wnt/ -Catenin Signaling in Glioma Stem Cells
- (2012) A. Gong et al. CANCER RESEARCH
- Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model
- (2012) Ananth K. Vellimana et al. JOURNAL OF NEURO-ONCOLOGY
- Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis
- (2012) Daniel Picard et al. LANCET ONCOLOGY
- The complex world of WNT receptor signalling
- (2012) Christof Niehrs NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Tangled Web of Non-Canonical Wnt Signalling in Neural Migration
- (2012) Charlotte E.J. Clark et al. NEUROSIGNALS
- Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibit, But Adipose Tissue-Derived Mesenchymal Stem Cells Promote, Glioblastoma Multiforme Proliferation
- (2012) Keiko Akimoto et al. STEM CELLS AND DEVELOPMENT
- The -Catenin Destruction Complex
- (2012) J. L. Stamos et al. Cold Spring Harbor Perspectives in Biology
- AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme
- (2011) O. L. Chinot et al. ADVANCES IN THERAPY
- FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis
- (2011) Nu Zhang et al. CANCER CELL
- Frizzled 4 Regulates Stemness and Invasiveness of Migrating Glioma Cells Established by Serial Intracranial Transplantation
- (2011) X. Jin et al. CANCER RESEARCH
- The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis
- (2011) Iris Augustin et al. EMBO Molecular Medicine
- All four zebrafish Wnt7 genes are expressed during early brain development
- (2011) Carlo A. Beretta et al. GENE EXPRESSION PATTERNS
- β-catenin/Tcf-4 complex transcriptionally regulates AKT1 in glioma
- (2011) Chunsheng Kang INTERNATIONAL JOURNAL OF ONCOLOGY
- Wnt Signaling Regulates Neuronal Differentiation of Cortical Intermediate Progenitors
- (2011) R. N. Munji et al. JOURNAL OF NEUROSCIENCE
- Regulation of NMDA-Receptor Synaptic Transmission by Wnt Signaling
- (2011) W. Cerpa et al. JOURNAL OF NEUROSCIENCE
- Wnt activation is implicated in glioblastoma radioresistance
- (2011) Yonghyun Kim et al. LABORATORY INVESTIGATION
- Cells of origin in cancer
- (2011) Jane E. Visvader NATURE
- En1 and Wnt signaling in midbrain dopaminergic neuronal development
- (2011) Maria TM Alves dos Santos et al. Neural Development
- The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence
- (2011) Wanyu L. Lambiv et al. NEURO-ONCOLOGY
- The dynamic role of beta-catenin in synaptic plasticity
- (2011) Kimberly A. Maguschak et al. NEUROPHARMACOLOGY
- Immunohistochemical Expression of Embryonic Stem Cell Markers in Malignant Rhabdoid Tumors
- (2011) Jeremy Deisch et al. PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
- MSCs: Biological characteristics, clinical applications and their outstanding concerns
- (2010) Yi-Ling Si et al. AGEING RESEARCH REVIEWS
- PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas
- (2010) Hongwu Zheng et al. CANCER CELL
- Human Bone Marrow-Derived MSCs Can Home to Orthotopic Breast Cancer Tumors and Promote Bone Metastasis
- (2010) R. H. Goldstein et al. CANCER RESEARCH
- Targeting Wnt Signaling: Can We Safely Eradicate Cancer Stem Cells?
- (2010) F. Takahashi-Yanaga et al. CLINICAL CANCER RESEARCH
- LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro
- (2010) E. Balzer et al. DEVELOPMENT
- The Wnt /β-catenin signaling pathway in the adult neurogenesis
- (2010) Lin Zhang et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors
- (2010) L. Grumolato et al. GENES & DEVELOPMENT
- The Imprinted GenePEG3Inhibits Wnt Signaling and Regulates Glioma Growth
- (2010) Xiuli Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LEF1/ -Catenin Complex Regulates Transcription of the Cav3.1 Calcium Channel Gene (Cacna1g) in Thalamic Neurons of the Adult Brain
- (2010) M. B. Wisniewska et al. JOURNAL OF NEUROSCIENCE
- Wnt-5a Modulates Recycling of Functional GABAA Receptors on Hippocampal Neurons
- (2010) L. Cuitino et al. JOURNAL OF NEUROSCIENCE
- Subtypes of medulloblastoma have distinct developmental origins
- (2010) Paul Gibson et al. NATURE
- Cross-species genomics matches driver mutations and cell compartments to model ependymoma
- (2010) Robert A. Johnson et al. NATURE
- Selective targeting of radiation-resistant tumor-initiating cells
- (2010) Mei Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
- (2009) B. T. Hennessy et al. CANCER RESEARCH
- Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling
- (2009) Yingwei Mao et al. CELL
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
- (2009) S. P.J. Fancy et al. GENES & DEVELOPMENT
- Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas
- (2009) Silke Götze et al. INTERNATIONAL JOURNAL OF CANCER
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1
- (2009) Y Zhu et al. LEUKEMIA
- Emerging roles of Wnts in the adult nervous system
- (2009) Nibaldo C. Inestrosa et al. NATURE REVIEWS NEUROSCIENCE
- Mechanisms and Functional Implications of Adult Neurogenesis
- (2008) Chunmei Zhao et al. CELL
- Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model
- (2008) Ling Qiao et al. CELL RESEARCH
- Retromer Retrieves Wntless
- (2008) Suzanne Eaton DEVELOPMENTAL CELL
- Cleavage of the Wnt Receptor Ryk Regulates Neuronal Differentiation during Cortical Neurogenesis
- (2008) Jungmook Lyu et al. DEVELOPMENTAL CELL
- Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
- (2008) Jing Yang et al. DEVELOPMENTAL CELL
- Regulation of Wnt protein secretion and its role in gradient formation
- (2008) Kerstin Bartscherer et al. EMBO REPORTS
- Glioblastoma multiforme: an emerging paradigm of anti-VEGF therapy
- (2008) David A Reardon et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Expression pattern of Wnt inhibitor factor 1(Wif1) during the development in mouse CNS
- (2008) Yu-An Hu et al. GENE EXPRESSION PATTERNS
- Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling
- (2008) Margaret H. Magdesian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
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