The Role of Necroptosis in Cardiovascular Disease

Prevention of Cardiovascular Disease

(2018) Brian V. Reamy et al.   PRIMARY CARE

Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway

(2018) Pingjun Zhu et al.   Redox Biology

CaMKII is a nodal signal for multiple programmed cell death pathways in heart

(2017) Ning Feng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Necroptosis may be a novel mechanism for cardiomyocyte death in acute myocarditis

(2017) Fei Zhou et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection

(2017) Megan H. Orzalli et al.   TRENDS IN CELL BIOLOGY

Necroptosis in neurodegenerative diseases: a potential therapeutic target

(2017) Shuo Zhang et al.   Cell Death & Disease

SALVIANOLIC ACID B ALLEVIATING MYOCARDIUM INJURY IN ISCHEMIA REPERFUSION RATS

(2016) Zengyong Qiao et al.   African Journal of Traditional Complementary and Alternative Medicines

RIP3-dependent necrosis induced inflammation exacerbates atherosclerosis

(2016) Lingjun Meng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biomarkers for the detection of necroptosis

(2016) Sudan He et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autonomic Nervous System in Viral Myocarditis: Pathophysiology and Therapy

(2016) Zheng Cheng et al.   CURRENT PHARMACEUTICAL DESIGN

Heat shock protein 70 inhibits cardiomyocyte necroptosis through repressing autophagy in myocardial ischemia/reperfusion injury

(2016) Xiaojuan Liu et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

MicroRNA-223-5p and -3p Cooperatively Suppress Necroptosis in Ischemic/Reperfused Hearts

(2016) Dongze Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis

(2016) Ting Zhang et al.   NATURE MEDICINE

Simvastatin pretreatment reduces caspase-9 and RIPK1 protein activity in rat cardiac allograft ischemia-reperfusion

(2016) Raimo Tuuminen et al.   TRANSPLANT IMMUNOLOGY

Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy

(2016) Mao-Bin Meng et al.   Oncotarget

Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

(2016) D. Karunakaran et al.   Science Advances

5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Inhibits RIPK1/RIPK3-Dependent Necroptosis in THP-1-Derived Foam Cells

(2016) Fang Tian et al.   Scientific Reports

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Viral myocarditis—diagnosis, treatment options and current controversies

(2015) Ari Pollack et al.   Nature Reviews Cardiology

Naringenin protects cardiac hypercholesterolemia-induced oxidative stress and subsequent necroptosis in rats

(2015) Yassine Chtourou et al.   Pharmacological Reports

RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality

(2015) Lingjun Meng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

(2014) Mark Luedde et al.   CARDIOVASCULAR RESEARCH

Oleuropein Offers Cardioprotection in Rats with Acute Myocardial Infarction

(2014) Zeinab Janahmadi et al.   Cardiovascular Toxicology

Transforming Growth Factor β–Activated Kinase 1 Signaling Pathway Critically Regulates Myocardial Survival and Remodeling

(2014) Lei Li et al.   CIRCULATION

Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

(2014) K. Newton et al.   SCIENCE

Necroptosis in health and diseases

(2014) Wen Zhou et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Study of Cardioprotective Effects of Necroptosis Inhibitors on Isolated Rat Heart Subjected to Global Ischemia–Reperfusion

(2013) Yu. V. Dmitriev et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

(2013) Xin Chen et al.   CELL RESEARCH

Physiologic Functions of Cyclophilin D and the Mitochondrial Permeability Transition Pore

(2013) John W. Elrod et al.   CIRCULATION JOURNAL

RIP3: a molecular switch for necrosis and inflammation

(2013) K. Moriwaki et al.   GENES & DEVELOPMENT

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

(2013) James M. Murphy et al.   IMMUNITY

Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemia–reperfusion injury

(2013) Shizuka Koshinuma et al.   Journal of Anesthesia

A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development

(2013) Juan Lin et al.   Cell Reports

Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia–reperfusion in vivo

(2012) Martinus I. F. J. Oerlemans et al.   BASIC RESEARCH IN CARDIOLOGY

Programmed Necrosis, Not Apoptosis, in the Heart

(2011) Gloria Kung et al.   CIRCULATION RESEARCH

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

(2011) Claudia Günther et al.   NATURE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance

(2010) Russell S. Whelan et al.   Annual Review of Physiology

Necroptosis as an alternative form of programmed cell death

(2010) Dana E Christofferson et al.   CURRENT OPINION IN CELL BIOLOGY

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

(2008) Junichi Hitomi et al.   CELL