Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia–reperfusion in vivo

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

Programmed Necrosis, Not Apoptosis, in the Heart

(2011) Gloria Kung et al.   CIRCULATION RESEARCH

Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance

(2010) Russell S. Whelan et al.   Annual Review of Physiology

Direct relationship between levels of TNF-α expression and endothelial dysfunction in reperfusion injury

(2010) Cuihua Zhang et al.   BASIC RESEARCH IN CARDIOLOGY

Inhibition of mitochondrial permeability transition pore opening: the holy grail of cardioprotection

(2010) Gerd Heusch et al.   BASIC RESEARCH IN CARDIOLOGY

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

(2010) Derek J. Hausenloy et al.   BASIC RESEARCH IN CARDIOLOGY

Active Wnt signaling in response to cardiac injury

(2010) Martinus I. F. J. Oerlemans et al.   BASIC RESEARCH IN CARDIOLOGY

Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase–ROS–CTGF pathway

(2010) Xuehui Liu et al.   CARDIOVASCULAR RESEARCH

MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1

(2010) Jia Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Necrostatin Decreases Oxidative Damage, Inflammation, and Injury after Neonatal HI

(2010) Frances J Northington et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure

(2010) Petra Kleinbongard et al.   PHARMACOLOGY & THERAPEUTICS

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

(2010) P. Vandenabeele et al.   Science Signaling

Cardioprotection and altered mitochondrial adenine nucleotide transport

(2009) Charles Steenbergen et al.   BASIC RESEARCH IN CARDIOLOGY

The mitochondrial permeability transition pore and ischemia-reperfusion injury

(2009) Christopher P. Baines   BASIC RESEARCH IN CARDIOLOGY

The mitochondrial permeability transition pore as a target for preconditioning and postconditioning

(2009) Derek J. Hausenloy et al.   BASIC RESEARCH IN CARDIOLOGY

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Reperfusion Injury, Microvascular Dysfunction, and Cardioprotection

(2009) Abhiram Prasad et al.   CIRCULATION

Coronary Microembolization

(2009) Gerd Heusch et al.   CIRCULATION

Heart Disease and Stroke Statistics—2010 Update

(2009) et al.   CIRCULATION

Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody

(2009) Fatih Arslan et al.   CIRCULATION

Biochemistry and physiology of mitochondrial ion channels involved in cardioprotection

(2009) Hirofumi Nishida et al.   FEBS LETTERS

Lack of Glutathione Peroxidase 1 Accelerates Cardiac-Specific Hypertrophy and Dysfunction in Angiotensin II Hypertension

(2009) Noelia Ardanaz et al.   HYPERTENSION

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

G i1 and G i3 Are Required for Epidermal Growth Factor-Mediated Activation of the Akt-mTORC1 Pathway

(2009) C. Cao et al.   Science Signaling

TNFα and reactive oxygen species in necrotic cell death

(2008) Michael J Morgan et al.   CELL RESEARCH

Cardioprotection

(2008) Gerd Heusch et al.   CIRCULATION

Role of NADPH oxidase in H9c2 cardiac muscle cells exposed to simulated ischaemia-reperfusion

(2008) Elisabetta Borchi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Necrostatin-1 Reduces Histopathology and Improves Functional Outcome after Controlled Cortical Impact in Mice

(2008) Zerong You et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Constitutive COX-2 activity in cardiomyocytes confers permanent cardioprotection

(2008) Javier Inserte et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology