Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells
出版年份 2018 全文链接
标题
Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells
作者
关键词
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出版物
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-04-18
DOI
10.3389/fphar.2018.00388
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis
- (2017) Andrea Iorga et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity
- (2017) Yongjie Zhang et al. TOXICOLOGY LETTERS
- Bilirubin-induced ER stress contributes to the inflammatory response and apoptosis in neuronal cells
- (2016) Mohammed Qaisiya et al. ARCHIVES OF TOXICOLOGY
- High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities
- (2016) Steven Wink et al. ARCHIVES OF TOXICOLOGY
- A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity
- (2016) Rowena L. Sison-Young et al. ARCHIVES OF TOXICOLOGY
- Characterization of human cytochrome P450 mediated bioactivation of amodiaquine and its major metabolite N-desethylamodiaquine
- (2016) Yongjie Zhang et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- How Reactive Metabolites Induce an Immune Response That Sometimes Leads to an Idiosyncratic Drug Reaction
- (2016) Tiffany Cho et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity
- (2016) Jiekun Xuan et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells
- (2016) Zhen Ren et al. TOXICOLOGICAL SCIENCES
- Simulation of interindividual differences in inactivation of reactive para -benzoquinone imine metabolites of diclofenac by glutathione S -transferases in human liver cytosol
- (2016) Michiel W. den Braver et al. TOXICOLOGY LETTERS
- Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α
- (2016) Houssein Al-Attrache et al. TOXICOLOGY LETTERS
- Polychlorinated Biphenyl Quinone Induces Endoplasmic Reticulum Stress, Unfolded Protein Response, and Calcium Release
- (2015) Demei Xu et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication
- (2015) Rowena L. C. Sison-Young et al. TOXICOLOGICAL SCIENCES
- High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical’s bio-activation with regards hepatotoxicity
- (2015) Ludovic Peyre et al. TOXICOLOGY IN VITRO
- Quantitative High Content Imaging of Cellular Adaptive Stress Response Pathways in Toxicity for Chemical Safety Assessment
- (2014) Steven Wink et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Involvement of Myeloperoxidase and NADPH Oxidase in the Covalent Binding of Amodiaquine and Clozapine to Neutrophils: Implications for Drug-Induced Agranulocytosis
- (2014) Alexandra R. Lobach et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Human NAD(P)H:quinone Oxidoreductase 1 (NQO1)-Mediated Inactivation of Reactive Quinoneimine Metabolites of Diclofenac and Mefenamic Acid
- (2014) Galvin Vredenburg et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways
- (2014) Gilda M. Kalinec et al. HEARING RESEARCH
- Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy
- (2014) K. K. Scarsi et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Drug-Induced Endoplasmic Reticulum and Oxidative Stress Responses Independently Sensitize Toward TNFα-Mediated Hepatotoxicity
- (2014) Lisa Fredriksson et al. TOXICOLOGICAL SCIENCES
- A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress
- (2014) Namrata Chaudhari et al. Frontiers in Cellular Neuroscience
- HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved
- (2013) Laia Tolosa et al. ARCHIVES OF TOXICOLOGY
- Glutathione-S-Transferases As Determinants of Cell Survival and Death
- (2012) Kenneth D. Tew et al. ANTIOXIDANTS & REDOX SIGNALING
- An overview of transcriptional regulation in response to toxicological insult
- (2012) Paul Jennings et al. ARCHIVES OF TOXICOLOGY
- Glutathione transferases, regulators of cellular metabolism and physiology
- (2012) Philip G. Board et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Mass Spectrometric Characterization of Protein Adducts of Multiple P450-Dependent Reactive Intermediates of Diclofenac to Human Glutathione-S-transferase P1-1
- (2012) Jan Simon Boerma et al. CHEMICAL RESEARCH IN TOXICOLOGY
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Pharmacokinetics of Amodiaquine and Desethylamodiaquine in Pregnant and Postpartum Women with Plasmodium vivax Malaria
- (2011) Marcus J. Rijken et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
- (2011) R. Okada et al. DRUG METABOLISM AND DISPOSITION
- CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay
- (2011) A. Iwamura et al. DRUG METABOLISM AND DISPOSITION
- Development of a Highly Sensitive Cytotoxicity Assay System for CYP3A4-Mediated Metabolic Activation
- (2011) H. Hosomi et al. DRUG METABOLISM AND DISPOSITION
- Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
- (2011) Ira Tabas et al. NATURE CELL BIOLOGY
- Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-κB
- (2010) Alvin J.L. Chia et al. BIOCHEMICAL PHARMACOLOGY
- Role of Human GlutathioneS-Transferases in the Inactivation of Reactive Metabolites of Clozapine
- (2010) Sanja Dragovic et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents
- (2010) Romina Nassini et al. FASEB JOURNAL
- Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice
- (2009) Shinji Shimizu et al. ARCHIVES OF TOXICOLOGY
- Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1
- (2009) Sandra L. Kabler et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Glutathione S-transferase expression and isoenzyme composition during cell differentiation of Caco-2 cells
- (2009) E. Scharmach et al. TOXICOLOGY
- Modulatory role of copper on β-naphthoflavone-induced DNA damage in European eel (Anguilla anguilla L.)
- (2008) I. Ahmad et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Validation of high performance liquid chromatography–electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate–amodiaquine drug combination
- (2008) Choon-Sheen Lai et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin
- (2008) Christina Peklak-Scott et al. MOLECULAR CANCER THERAPEUTICS
- BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals
- (2008) Ina Poser et al. NATURE METHODS
- Glutathione-S-transferase pi as a model protein for the characterisation of chemically reactive metabolites
- (2008) Rosalind E. Jenkins et al. PROTEOMICS
- Amodiaquine-induced oxidative stress in a hepatocyte inflammation model
- (2008) Shahrzad Tafazoli et al. TOXICOLOGY
- The Nrf2–Keap1 defence pathway: Role in protection against drug-induced toxicity
- (2007) Ian M. Copple et al. TOXICOLOGY
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