Overexpression of HACE1 in gastric cancer inhibits tumor aggressiveness by impeding cell proliferation and migration

Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation

(2017) Emilie Andrio et al.   Scientific Reports

New miRNA expression abnormalities in laryngeal squamous cell carcinoma

(2016) Magdalena Cybula et al.   Cancer Biomarkers

NLRC5 regulates cell proliferation, migration and invasion in hepatocellular carcinoma by targeting the Wnt/β-catenin signaling pathway

(2016) Yun-yun Peng et al.   CANCER LETTERS

HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations

(2016) Abdelilah Bouzelfen et al.   LEUKEMIA RESEARCH

Tumor-suppressive role of HACE1 in hepatocellular carcinoma and its clinical significance

(2016) Zeng-Fa Gao et al.   ONCOLOGY REPORTS

TNF-driven cell fate: till HACE do us part

(2016) Luigi Tortola et al.   Oncotarget

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

(2016) Luigi Tortola et al.   Cell Reports

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals

(2015) Jingjing Qi et al.   GUT

Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression

(2015) E T Goka et al.   ONCOGENE

MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway

(2015) Tong Liu et al.   Oncotarget

Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression

(2014) Zhengzhao Liu et al.   CANCER CELL

Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction

(2014) N Cetinbas et al.   ONCOGENE

Huwe1-Mediated Ubiquitylation of Dishevelled Defines a Negative Feedback Loop in the Wnt Signaling Pathway

(2014) R. E. A. de Groot et al.   Science Signaling

Mammalian HECT ubiquitin-protein ligases: Biological and pathophysiological aspects

(2013) Martin Scheffner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Gene methylation in gastric cancer

(2013) Yiping Qu et al.   CLINICA CHIMICA ACTA

HECT Domain-containing E3 Ubiquitin Ligase NEDD4L Negatively Regulates Wnt Signaling by Targeting Dishevelled for Proteasomal Degradation

(2013) Yi Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smurf1-Mediated Lys29-Linked Nonproteolytic Polyubiquitination of Axin Negatively Regulates Wnt/ -Catenin Signaling

(2013) C. Fei et al.   MOLECULAR AND CELLULAR BIOLOGY

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

(2013) Mads Daugaard et al.   Nature Communications

HACE1 Is a Tumor Suppressor Gene Candidate in Natural Killer Cell Neoplasms

(2012) Can Küçük et al.   AMERICAN JOURNAL OF PATHOLOGY