Twin DNA Methylation Profiling Reveals Flare-Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

Concordance of autoimmune disease in a nationwide Danish systemic lupus erythematosus twin cohort

(2018) Constance Jensina Ulff-Møller et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

(2016) Juliana Imgenberg-Kreuz et al.   ANNALS OF THE RHEUMATIC DISEASES

IFI44Lpromoter methylation as a blood biomarker for systemic lupus erythematosus

(2016) Ming Zhao et al.   ANNALS OF THE RHEUMATIC DISEASES

Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

(2016) Christoph Bock et al.   NATURE BIOTECHNOLOGY

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

(2016) David L Morris et al.   NATURE GENETICS

Genome-wide profiling in treatment-naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes

(2016) John R Glossop et al.   Epigenomics

DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

(2016) Andrew E Teschendorff et al.   Nature Communications

Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome

(2015) Corinne Miceli-Richard et al.   ANNALS OF THE RHEUMATIC DISEASES

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells

(2015) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

(2015) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Association of BAFF, APRIL serum levels, BAFF-R, TACI and BCMA expression on peripheral B-cell subsets with clinical manifestations in systemic lupus erythematosus

(2015) D C Salazar-Camarena et al.   LUPUS

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

(2015) Marta Kulis et al.   NATURE GENETICS

EpiFactors: a comprehensive database of human epigenetic factors and complexes

(2015) Yulia A. Medvedeva et al.   Database-The Journal of Biological Databases and Curation

Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families

(2015) Chang-Fu Kuo et al.   JAMA Internal Medicine

Is the risk of tumour necrosis factor inhibitor-induced lupus or lupus-like syndrome the same with monoclonal antibodies and soluble receptor? A case/non-case study in a nationwide pharmacovigilance database

(2014) Guillaume Moulis et al.   RHEUMATOLOGY

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

(2013) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

(2013) Amy M. Becker et al.   PLoS One

Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations

(2013) Devin M. Absher et al.   PLoS Genetics

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Taming lupus—a new understanding of pathogenesis is leading to clinical advances

(2012) Zheng Liu et al.   NATURE MEDICINE

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation

(2012) Nizar Touleimat et al.   Epigenomics

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

(2011) B. W. Higgs et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

(2011) Matlock Jeffries et al.   Epigenetics

Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions

(2011) Joanne M. Hildebrand et al.   IMMUNOLOGICAL REVIEWS

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE

Epigenetic alterations in autoimmune rheumatic diseases

(2011) Esteban Ballestar   Nature Reviews Rheumatology

The Danish Twin Registry

(2011) Axel Skytthe et al.   SCANDINAVIAN JOURNAL OF PUBLIC HEALTH

The Danish National Patient Register

(2011) Elsebeth Lynge et al.   SCANDINAVIAN JOURNAL OF PUBLIC HEALTH

Cytokine disturbances in systemic lupus erythematosus

(2011) Noam Jacob et al.   ARTHRITIS RESEARCH & THERAPY

Epigenetics Lessons from Twins: Prospects for Autoimmune Disease

(2009) Esteban Ballestar   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Sporadic cases are the norm for complex disease

(2009) Jian Yang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

(2009) B. M. Javierre et al.   GENOME RESEARCH